Stahl SH[au] - Search Results

Year	Number of Results
2014	2
2015	3
2016	1
2017	2
2018	4
2020	1
2021	1
2022	4
2023	0

1

Leveraging microphysiological systems to address challenges encountered during development of oligonucleotide therapeutics.

Ramsden D, Belair DG, Agarwal S, Andersson P, Humphreys S, Dalmas DA, Stahl SH, Maclauchlin C, Cichocki JA. Ramsden D, et al. Among authors: stahl sh. ALTEX. 2022;39(2):273–296. doi: 10.14573/altex.2108241. Epub 2021 Nov 11. ALTEX. 2022. PMID: 34766620 Free article. Review.

2

Challenges and Opportunities for Improved Drug-Drug Interaction Predictions for Renal OCT2 and MATE1/2-K Transporters.

Krishnan S, Ramsden D, Ferguson D, Stahl SH, Wang J, McGinnity DF, Hariparsad N. Krishnan S, et al. Among authors: stahl sh. Clin Pharmacol Ther. 2022 Sep;112(3):562-572. doi: 10.1002/cpt.2666. Epub 2022 Jun 25. Clin Pharmacol Ther. 2022. PMID: 35598119 Review.

3

Systems toxicology: modelling biomarkers of glutathione homeostasis and paracetamol metabolism.

Stahl SH, Yates JW, Nicholls AW, Kenna JG, Coen M, Ortega F, Nicholson JK, Wilson ID. Stahl SH, et al. Drug Discov Today Technol. 2015 Aug;15:9-14. doi: 10.1016/j.ddtec.2015.06.003. Epub 2015 Jul 16. Drug Discov Today Technol. 2015. PMID: 26464084 Free article. Review.

4

Perspective on the Application of Microphysiological Systems to Drug Transporter Studies.

Caetano-Pinto P, Stahl SH. Caetano-Pinto P, et al. Among authors: stahl sh. Drug Metab Dispos. 2018 Nov;46(11):1647-1657. doi: 10.1124/dmd.118.082750. Epub 2018 Aug 22. Drug Metab Dispos. 2018. PMID: 30135246 Review.

5

Regulation of Drug Transport Proteins-From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium.

Brouwer KLR, Evers R, Hayden E, Hu S, Li CY, Meyer Zu Schwabedissen HE, Neuhoff S, Oswald S, Piquette-Miller M, Saran C, Sjöstedt N, Sprowl JA, Stahl SH, Yue W. Brouwer KLR, et al. Among authors: stahl sh. Clin Pharmacol Ther. 2022 Sep;112(3):461-484. doi: 10.1002/cpt.2605. Epub 2022 May 24. Clin Pharmacol Ther. 2022. PMID: 35390174 Free PMC article. Review.

6

Amplifying the impact of kidney microphysiological systems: predicting renal drug clearance using mechanistic modelling based on reconstructed drug secretion.

Caetano-Pinto P, Nordell P, Nieskens T, Haughan K, Fenner KS, Stahl SH. Caetano-Pinto P, et al. Among authors: stahl sh. ALTEX. 2022 Nov 3. doi: 10.14573/altex.2204011. Online ahead of print. ALTEX. 2022. PMID: 36343109 Free article.

7

Using Quantitative Systems Toxicology to Investigate Observed Species Differences in CKA-Mediated Hepatotoxicity.

Battista C, Yang K, Stahl SH, Mettetal JT, Watkins PB, Siler SQ, Howell BA. Battista C, et al. Among authors: stahl sh. Toxicol Sci. 2018 Nov 1;166(1):123-130. doi: 10.1093/toxsci/kfy191. Toxicol Sci. 2018. PMID: 30060248 Free PMC article. Clinical Trial.

8

Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters.

Yang K, Battista C, Woodhead JL, Stahl SH, Mettetal JT, Watkins PB, Siler SQ, Howell BA. Yang K, et al. Among authors: stahl sh. Clin Pharmacol Ther. 2017 Apr;101(4):501-509. doi: 10.1002/cpt.619. Epub 2017 Feb 17. Clin Pharmacol Ther. 2017. PMID: 28074467 Free PMC article.

9

The analysis of acetaminophen (paracetamol) and seven metabolites in rat, pig and human plasma by U(H)PLC-MS.

Dargue R, Grant I, Nye LC, Nicholls A, Dare T, Stahl SH, Plumb RS, Lee K, Jalan R, Coen M, Wilson ID. Dargue R, et al. Among authors: stahl sh. Bioanalysis. 2020 Apr;12(7):485-500. doi: 10.4155/bio-2020-0015. Epub 2020 Apr 28. Bioanalysis. 2020. PMID: 32343149 Free article.

10

Mechanistic Modeling Reveals the Critical Knowledge Gaps in Bile Acid-Mediated DILI.

Woodhead JL, Yang K, Brouwer KL, Siler SQ, Stahl SH, Ambroso JL, Baker D, Watkins PB, Howell BA. Woodhead JL, et al. Among authors: stahl sh. CPT Pharmacometrics Syst Pharmacol. 2014 Jul 9;3(7):e123. doi: 10.1038/psp.2014.21. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 25006780 Free PMC article.

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