Search Page

1

Cite

Share

Capillary microsampling in clinical studies: opportunities and challenges in two case studies.

Verhaeghe T, Meulder M, Hillewaert V, Dillen L, Stieltjes H. Verhaeghe T, et al. Among authors: stieltjes h. Bioanalysis. 2020 Jul;12(13):905-918. doi: 10.4155/bio-2020-0054. Epub 2020 Jul 6. Bioanalysis. 2020. PMID: 32628039

Cite

Share

2

Cite

Share

Bioequivalence and food effect of a fixed-dose combination of macitentan and tadalafil: Adaptive design in the COVID-19 pandemic.

Csonka D, Fishman V, Natarajan J, Stieltjes H, Armas D, Dishy V, Perez Ruixo JJ. Csonka D, et al. Among authors: stieltjes h. Pharmacol Res Perspect. 2021 Oct;9(5):e00846. doi: 10.1002/prp2.846. Pharmacol Res Perspect. 2021. PMID: 34624174 Free PMC article. Clinical Trial.

Cite

Share

3

Cite

Share

The application of capillary microsampling in GLP toxicology studies.

Verhaeghe T, Dillen L, Stieltjes H, Zwart L, Feyen B, Diels L, Vroman A, Timmerman P. Verhaeghe T, et al. Among authors: stieltjes h. Bioanalysis. 2017 Apr;9(7):531-540. doi: 10.4155/bio-2016-0297. Epub 2017 Mar 16. Bioanalysis. 2017. PMID: 28300424

Cite

Share

4

Cite

Share

Comparison of toxicokinetic parameters of a drug and two metabolites following traditional and capillary microsampling in rat.

Verhaeghe T, Dillen L, Stieltjes H, Zwart L, Feyen B. Verhaeghe T, et al. Among authors: stieltjes h. Bioanalysis. 2019 Jun;11(13):1233-1242. doi: 10.4155/bio-2019-0085. Epub 2019 Jul 12. Bioanalysis. 2019. PMID: 31298569

Cite

Share

5

Cite

Share

Effect of canagliflozin on the pharmacokinetics of glyburide, metformin, and simvastatin in healthy participants.

Devineni D, Manitpisitkul P, Murphy J, Skee D, Wajs E, Mamidi RN, Tian H, Vandebosch A, Wang SS, Verhaeghe T, Stieltjes H, Usiskin K. Devineni D, et al. Among authors: stieltjes h. Clin Pharmacol Drug Dev. 2015 May-Jun;4(3):226-36. doi: 10.1002/cpdd.166. Epub 2014 Oct 27. Clin Pharmacol Drug Dev. 2015. PMID: 27140803 Clinical Trial.

Cite

Share

6

Cite

Share

Absolute oral bioavailability and pharmacokinetics of canagliflozin: A microdose study in healthy participants.

Devineni D, Murphy J, Wang SS, Stieltjes H, Rothenberg P, Scheers E, Mamidi RN. Devineni D, et al. Among authors: stieltjes h. Clin Pharmacol Drug Dev. 2015 Jul;4(4):295-304. doi: 10.1002/cpdd.162. Epub 2014 Dec 11. Clin Pharmacol Drug Dev. 2015. PMID: 27136910 Clinical Trial.

Cite

Share

7

Cite

Share

Pharmacokinetics of abiraterone in healthy Japanese men: dose-proportionality and effect of food timing.

Inoue K, Shishido A, Vaccaro N, Jiao J, Stieltjes H, Bernard A, Yu M, Chien C. Inoue K, et al. Among authors: stieltjes h. Cancer Chemother Pharmacol. 2015 Jan;75(1):49-58. doi: 10.1007/s00280-014-2616-4. Epub 2014 Oct 25. Cancer Chemother Pharmacol. 2015. PMID: 25344090 Clinical Trial.

Cite

Share

8

Cite

Share

Impact on abiraterone pharmacokinetics and safety: Open-label drug-drug interaction studies with ketoconazole and rifampicin.

Bernard A, Vaccaro N, Acharya M, Jiao J, Monbaliu J, De Vries R, Stieltjes H, Yu M, Tran N, Chien C. Bernard A, et al. Among authors: stieltjes h. Clin Pharmacol Drug Dev. 2015 Jan;4(1):63-73. doi: 10.1002/cpdd.132. Epub 2014 Jun 27. Clin Pharmacol Drug Dev. 2015. PMID: 27128004

Cite

Share

9

Cite

Share

Pharmacokinetics, Pharmacodynamics, and Safety of Single-Dose Canagliflozin in Healthy Chinese Subjects.

Chen X, Hu P, Vaccaro N, Polidori D, Curtin CR, Stieltjes H, Sha S, Weiner S, Devineni D. Chen X, et al. Among authors: stieltjes h. Clin Ther. 2015 Jul 1;37(7):1483-1492.e1. doi: 10.1016/j.clinthera.2015.04.015. Epub 2015 Jun 3. Clin Ther. 2015. PMID: 26048186 Clinical Trial.

Cite

Share

10

Cite

Share

Single-dose pharmacokinetic studies of abiraterone acetate in men with hepatic or renal impairment.

Marbury T, Lawitz E, Stonerock R, Gonzalez M, Jiao J, Breeding J, Haqq C, Verboven P, Stieltjes H, Yu M, Molina A, Acharya M, Chien C, Tran N. Marbury T, et al. Among authors: stieltjes h. J Clin Pharmacol. 2014 Jul;54(7):732-41. doi: 10.1002/jcph.253. Epub 2014 Jan 17. J Clin Pharmacol. 2014. PMID: 24374856 Clinical Trial.

Cite

Share