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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1968 1
1970 1
1974 1
1977 1
1978 2
1979 2
1980 2
1981 3
1982 1
1984 1
1986 1
1988 4
1989 4
1990 6
1993 2
1994 1
1995 1
1996 2
1997 1
1998 1
1999 6
2000 4
2002 3
2003 2
2004 2
2006 1
2007 4
2008 1
2009 2
2010 4
2011 2
2012 1
2013 1
2014 1
2016 1
2017 2
2018 1
2019 6
2020 2
2021 1
2023 2
2024 0

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84 results

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Page 1
Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain.
Burke JR, Cheng L, Gillooly KM, Strnad J, Zupa-Fernandez A, Catlett IM, Zhang Y, Heimrich EM, McIntyre KW, Cunningham MD, Carman JA, Zhou X, Banas D, Chaudhry C, Li S, D'Arienzo C, Chimalakonda A, Yang X, Xie JH, Pang J, Zhao Q, Rose SM, Huang J, Moslin RM, Wrobleski ST, Weinstein DS, Salter-Cid LM. Burke JR, et al. Among authors: strnad j. Sci Transl Med. 2019 Jul 24;11(502):eaaw1736. doi: 10.1126/scitranslmed.aaw1736. Sci Transl Med. 2019. PMID: 31341059
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165.
Wrobleski ST, Moslin R, Lin S, Zhang Y, Spergel S, Kempson J, Tokarski JS, Strnad J, Zupa-Fernandez A, Cheng L, Shuster D, Gillooly K, Yang X, Heimrich E, McIntyre KW, Chaudhry C, Khan J, Ruzanov M, Tredup J, Mulligan D, Xie D, Sun H, Huang C, D'Arienzo C, Aranibar N, Chiney M, Chimalakonda A, Pitts WJ, Lombardo L, Carter PH, Burke JR, Weinstein DS. Wrobleski ST, et al. Among authors: strnad j. J Med Chem. 2019 Oct 24;62(20):8973-8995. doi: 10.1021/acs.jmedchem.9b00444. Epub 2019 Jul 18. J Med Chem. 2019. PMID: 31318208
Oestrogens and Alzheimer's disease.
Birkhäuser MH, Strnad J, Kämpf C, Bahro M. Birkhäuser MH, et al. Among authors: strnad j. Int J Geriatr Psychiatry. 2000 Jul;15(7):600-9. doi: 10.1002/1099-1166(200007)15:7<600::aid-gps155>;2-7. Int J Geriatr Psychiatry. 2000. PMID: 10918340 Review.
[Depression in old age].
Strnad J, Bahro M. Strnad J, et al. Schweiz Med Wochenschr. 1999 Aug 21;129(33):1162-70. Schweiz Med Wochenschr. 1999. PMID: 10483669 Review. German.
Major depressive disorder in the general hospital: adaptation of clinical practice guidelines.
Voellinger R, Berney A, Baumann P, Annoni JM, Bryois C, Buclin T, Büla C, Camus V, Christin L, Cornuz J, de Goumoëns P, Lamy O, Strnad J, Burnand B, Stiefel F. Voellinger R, et al. Among authors: strnad j. Gen Hosp Psychiatry. 2003 May-Jun;25(3):185-93. doi: 10.1016/s0163-8343(03)00009-4. Gen Hosp Psychiatry. 2003. PMID: 12748031 Review.
Discovery of BMS-986202: A Clinical Tyk2 Inhibitor that Binds to Tyk2 JH2.
Liu C, Lin J, Langevine C, Smith D, Li J, Tokarski JS, Khan J, Ruzanov M, Strnad J, Zupa-Fernandez A, Cheng L, Gillooly KM, Shuster D, Zhang Y, Thankappan A, McIntyre KW, Chaudhry C, Elzinga PA, Chiney M, Chimalakonda A, Lombardo LJ, Macor JE, Carter PH, Burke JR, Weinstein DS. Liu C, et al. Among authors: strnad j. J Med Chem. 2021 Jan 14;64(1):677-694. doi: 10.1021/acs.jmedchem.0c01698. Epub 2020 Dec 28. J Med Chem. 2021. PMID: 33370104
Structure-activity relationship study of central pyridine-derived TYK2 JH2 inhibitors: Optimization of the PK profile through C4' and C6 variations.
Xiao Z, Yang MG, Liu C, Sherwood T, Gilmore JL, Lin J, Li P, Wu DR, Tokarski J, Li S, Cheng L, Xie C, Fan J, Dierks E, Strnad J, Cvijic ME, Khan J, Ruzanov M, Galella M, Khandelwal P, Dyckman AJ, Mathur A, Lombardo LJ, Macor JE, Carter PH, Aranibar N, Burke JR, Weinstein DS. Xiao Z, et al. Among authors: strnad j. Bioorg Med Chem Lett. 2023 Jul 15;91:129373. doi: 10.1016/j.bmcl.2023.129373. Epub 2023 Jun 12. Bioorg Med Chem Lett. 2023. PMID: 37315697
84 results