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The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
Pras A, Houben B, Aprile FA, Seinstra R, Gallardo R, Janssen L, Hogewerf W, Gallrein C, De Vleeschouwer M, Mata-Cabana A, Koopman M, Stroo E, de Vries M, Louise Edwards S, Kirstein J, Vendruscolo M, Falsone SF, Rousseau F, Schymkowitz J, Nollen EAA. Pras A, et al. Among authors: stroo e. EMBO J. 2021 Nov 2;40(21):e107568. doi: 10.15252/embj.2020107568. Epub 2021 Oct 7. EMBO J. 2021. PMID: 34617299 Free PMC article.
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain.
Stroo E, Janssen L, Sin O, Hogewerf W, Koster M, Harkema L, Youssef SA, Beschorner N, Wolters AH, Bakker B, Becker L, Garrett L, Marschall S, Hoelter SM, Wurst W, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Thathiah A, Foijer F, van de Sluis B, van Deursen J, Jucker M, de Bruin A, Nollen EA. Stroo E, et al. Life Sci Alliance. 2023 May 2;6(7):e202201730. doi: 10.26508/lsa.202201730. Print 2023 Jul. Life Sci Alliance. 2023. PMID: 37130781 Free PMC article.
Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation.
Sin O, de Jong T, Mata-Cabana A, Kudron M, Zaini MA, Aprile FA, Seinstra RI, Stroo E, Prins RW, Martineau CN, Wang HH, Hogewerf W, Steinhof A, Wanker EE, Vendruscolo M, Calkhoven CF, Reinke V, Guryev V, Nollen EA. Sin O, et al. Among authors: stroo e. Mol Cell. 2017 Mar 16;65(6):1096-1108.e6. doi: 10.1016/j.molcel.2017.02.022. Mol Cell. 2017. PMID: 28306505 Free PMC article.