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Mechanism of efavirenz influence on methadone pharmacokinetics and pharmacodynamics.
Kharasch ED, Whittington D, Ensign D, Hoffer C, Bedynek PS, Campbell S, Stubbert K, Crafford A, London A, Kim T. Kharasch ED, et al. Among authors: stubbert k. Clin Pharmacol Ther. 2012 Apr;91(4):673-84. doi: 10.1038/clpt.2011.276. Epub 2012 Mar 7. Clin Pharmacol Ther. 2012. PMID: 22398970 Free PMC article.
The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine.
Montana MC, Cavallone LF, Stubbert KK, Stefanescu AD, Kharasch ED, Gereau RW 4th. Montana MC, et al. Among authors: stubbert kk. J Pharmacol Exp Ther. 2009 Sep;330(3):834-43. doi: 10.1124/jpet.109.154138. Epub 2009 Jun 10. J Pharmacol Exp Ther. 2009. PMID: 19515968 Free PMC article.