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1986 2
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68 results

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Page 1
Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists.
Kosar M, Sarott RC, Sykes DA, Viray AEG, Vitale RM, Tomašević N, Li X, Ganzoni RLZ, Kicin B, Reichert L, Patej KJ, Gómez-Bouzó U, Guba W, McCormick PJ, Hua T, Gruber CW, Veprintsev DB, Frank JA, Grether U, Carreira EM. Kosar M, et al. Among authors: sykes da. ACS Cent Sci. 2024 Mar 11;10(5):956-968. doi: 10.1021/acscentsci.3c01461. eCollection 2024 May 22. ACS Cent Sci. 2024. PMID: 38799662 Free PMC article.
Binding kinetics of ligands acting at GPCRs.
Sykes DA, Stoddart LA, Kilpatrick LE, Hill SJ. Sykes DA, et al. Mol Cell Endocrinol. 2019 Apr 5;485:9-19. doi: 10.1016/j.mce.2019.01.018. Epub 2019 Feb 8. Mol Cell Endocrinol. 2019. PMID: 30738950 Free PMC article. Review.
Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects.
Aebi J, Atz K, Ametamey SM, Benz J, Blaising J, Butini S, Campiani G, Carreira EM, Collin L, De Lago E, Gazzi T, Gertsch J, Gobbi L, Guba W, Fernández-Ruiz J, Fingerle J, Haider A, He Y, Heitman LH, Honer M, Hunziker D, Kuhn B, Maccarrone M, Märki HP, Martin RE, Mohr P, Mu L, Nazaré M, Nippa DF, Oddi S, O'Hara F, Pacher P, Romero J, Röver S, Rufer AC, Schibli R, Schneider G, Stepan AF, Sykes DA, Ullmer C, Van der Stelt M, Veprintsev DB, Wittwer MB, Grether U. Aebi J, et al. Among authors: sykes da. Chimia (Aarau). 2024 Aug 21;78(7-8):499-512. doi: 10.2533/chimia.2024.499. Chimia (Aarau). 2024. PMID: 39221845 Free article.
GPCR Solubilization and Quality Control.
Miljus T, Sykes DA, Harwood CR, Vuckovic Z, Veprintsev DB. Miljus T, et al. Among authors: sykes da. Methods Mol Biol. 2020;2127:105-127. doi: 10.1007/978-1-0716-0373-4_8. Methods Mol Biol. 2020. PMID: 32112318
How to start an awake spine program: Protocol and illustrative cases.
Waguia R, Touko EK, Sykes DAW, Kelly-Hedrick M, Hijji FY, Sharan AD, Foster N, Abd-El-Barr MM. Waguia R, et al. Among authors: sykes daw. IBRO Neurosci Rep. 2022 Jun 8;13:69-77. doi: 10.1016/j.ibneur.2022.05.009. eCollection 2022 Dec. IBRO Neurosci Rep. 2022. PMID: 35789808 Free PMC article. Review.
A 13-Year-Old Girl With Unilateral Visual Changes.
Sykes DAW, Joseph SL, Williams SP, Das SU. Sykes DAW, et al. J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096221150635. doi: 10.1177/23247096221150635. J Investig Med High Impact Case Rep. 2023. PMID: 36738077 Free PMC article.
Highly Selective Drug-Derived Fluorescent Probes for the Cannabinoid Receptor Type 1 (CB1R).
Mach L, Omran A, Bouma J, Radetzki S, Sykes DA, Guba W, Li X, Höffelmeyer C, Hentsch A, Gazzi T, Mostinski Y, Wasinska-Kalwa M, de Molnier F, van der Horst C, von Kries JP, Vendrell M, Hua T, Veprintsev DB, Heitman LH, Grether U, Nazare M. Mach L, et al. Among authors: sykes da. J Med Chem. 2024 Jul 25;67(14):11841-11867. doi: 10.1021/acs.jmedchem.4c00465. Epub 2024 Jul 11. J Med Chem. 2024. PMID: 38990855 Free PMC article.
Associations between urbanicity and spinal cord astrocytoma management and outcomes.
Sykes DAW, Waguia R, Abu-Bonsrah N, Price M, Dalton T, Sperber J, Owolo E, Hockenberry H, Bishop B, Kruchko C, Barnholtz-Sloan JS, Erickson M, Ostrom QT, Goodwin CR. Sykes DAW, et al. Cancer Epidemiol. 2023 Oct;86:102431. doi: 10.1016/j.canep.2023.102431. Epub 2023 Jul 19. Cancer Epidemiol. 2023. PMID: 37478632
68 results