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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 2
1987 2
1988 1
1990 1
1991 1
1993 1
2005 1
2007 2
2009 1
2010 1
2012 4
2014 2
2015 3
2016 5
2017 3
2018 2
2019 5
2020 3
2021 0
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39 results
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Page 1
Binding kinetics of ligands acting at GPCRs.
Sykes DA, Stoddart LA, Kilpatrick LE, Hill SJ. Sykes DA, et al. Mol Cell Endocrinol. 2019 Apr 5;485:9-19. doi: 10.1016/j.mce.2019.01.018. Epub 2019 Feb 8. Mol Cell Endocrinol. 2019. PMID: 30738950 Free PMC article. Review.
GPCR Solubilization and Quality Control.
Miljus T, Sykes DA, Harwood CR, Vuckovic Z, Veprintsev DB. Miljus T, et al. Among authors: sykes da. Methods Mol Biol. 2020;2127:105-127. doi: 10.1007/978-1-0716-0373-4_8. Methods Mol Biol. 2020. PMID: 32112318
Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs.
Bradley SJ, Molloy C, Valuskova P, Dwomoh L, Scarpa M, Rossi M, Finlayson L, Svensson KA, Chernet E, Barth VN, Gherbi K, Sykes DA, Wilson CA, Mistry R, Sexton PM, Christopoulos A, Mogg AJ, Rosethorne EM, Sakata S, John Challiss RA, Broad LM, Tobin AB. Bradley SJ, et al. Among authors: sykes da. Nat Chem Biol. 2020 Mar;16(3):240-249. doi: 10.1038/s41589-019-0453-9. Epub 2020 Feb 20. Nat Chem Biol. 2020. PMID: 32080630
Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells.
Sarott RC, Westphal MV, Pfaff P, Korn C, Sykes DA, Gazzi T, Brennecke B, Atz K, Weise M, Mostinski Y, Hompluem P, Koers E, Miljuš T, Roth NJ, Asmelash H, Vong MC, Piovesan J, Guba W, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Benito-Cuesta I, Grande T, Ruiz de Martı N Esteban S, Yeliseev A, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Yuan CY, Drobyski WR, Saroz Y, Grimsey N, Honer M, Fingerle J, Gawrisch K, Romero J, Hillard CJ, Varga ZV, van der Stelt M, Pacher P, Gertsch J, McCormick PJ, Ullmer C, Oddi S, Maccarrone M, Veprintsev DB, Nazaré M, Grether U, Carreira EM. Sarott RC, et al. Among authors: sykes da. J Am Chem Soc. 2020 Oct 7;142(40):16953-16964. doi: 10.1021/jacs.0c05587. Epub 2020 Sep 29. J Am Chem Soc. 2020. PMID: 32902974
Pharmacological Characterization of a Novel 5-Hydroxybenzothiazolone-Derived β 2-Adrenoceptor Agonist with Functional Selectivity for Anabolic Effects on Skeletal Muscle Resulting in a Wider Cardiovascular Safety Window in Preclinical Studies.
Koziczak-Holbro M, Rigel DF, Dumotier B, Sykes DA, Tsao J, Nguyen NH, Bösch J, Jourdain M, Flotte L, Adachi Y, Kiffe M, Azria M, Fairhurst RA, Charlton SJ, Richardson BP, Lach-Trifilieff E, Glass DJ, Ullrich T, Hatakeyama S. Koziczak-Holbro M, et al. Among authors: sykes da. J Pharmacol Exp Ther. 2019 May;369(2):188-199. doi: 10.1124/jpet.118.255307. Epub 2019 Feb 28. J Pharmacol Exp Ther. 2019. PMID: 30819762
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