Genome-wide RNAi Screening Identifies RFC4 as a Factor That Mediates Radioresistance in Colorectal Cancer by Facilitating Nonhomologous End Joining Repair.
Wang XC, Yue X, Zhang RX, Liu TY, Pan ZZ, Yang MJ, Lu ZH, Wang ZY, Peng JH, Le LY, Wang GY, Peng QH, Meng Y, Huang W, Liu RY.
Wang XC, et al.
Clin Cancer Res. 2019 Jul 15;25(14):4567-4579. doi: 10.1158/1078-0432.CCR-18-3735. Epub 2019 Apr 12.
Clin Cancer Res. 2019.
PMID: 30979744
Finally, the relationships between RFC4 expression and clinical parameters and outcomes were investigated in 145 patients with LARC receiving neoCRT. RESULTS: RFC4, NCAPH, SYNE3, LDLRAD2, NHP2, and FICD were identified as potential candidate radioresistance genes. ...
Finally, the relationships between RFC4 expression and clinical parameters and outcomes were investigated in 145 patients with LARC receivin …