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Inhibition of B cell receptor-mediated activation of primary human B cells by coengagement of CD19 and FcgammaRIIb with Fc-engineered antibodies.

Chu SY, Vostiar I, Karki S, Moore GL, Lazar GA, Pong E, Joyce PF, Szymkowski DE, Desjarlais JR. Chu SY, et al. Among authors: szymkowski de. Mol Immunol. 2008 Sep;45(15):3926-33. doi: 10.1016/j.molimm.2008.06.027. Epub 2008 Aug 8. Mol Immunol. 2008. PMID: 18691763

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Harnessing Fc receptor biology in the design of therapeutic antibodies.

Sondermann P, Szymkowski DE. Sondermann P, et al. Among authors: szymkowski de. Curr Opin Immunol. 2016 Jun;40:78-87. doi: 10.1016/j.coi.2016.03.005. Epub 2016 Mar 30. Curr Opin Immunol. 2016. PMID: 27038127 Review.

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Topical Administration of a Soluble TNF Inhibitor Reduces Infarct Volume After Focal Cerebral Ischemia in Mice.

Yli-Karjanmaa M, Clausen BH, Degn M, Novrup HG, Ellman DG, Toft-Jensen P, Szymkowski DE, Stensballe A, Meyer M, Brambilla R, Lambertsen KL. Yli-Karjanmaa M, et al. Among authors: szymkowski de. Front Neurosci. 2019 Aug 7;13:781. doi: 10.3389/fnins.2019.00781. eCollection 2019. Front Neurosci. 2019. PMID: 31440125 Free PMC article.

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Inhibition of B cell activation following in vivo co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice.

Chu SY, Pong E, Bonzon C, Yu N, Jacob CO, Chalmers SA, Putterman C, Szymkowski DE, Stohl W. Chu SY, et al. Among authors: szymkowski de. J Transl Autoimmun. 2020 Dec 15;4:100075. doi: 10.1016/j.jtauto.2020.100075. eCollection 2021. J Transl Autoimmun. 2020. PMID: 33409482 Free PMC article.

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Roles of soluble and membrane TNF and related ligands in mycobacterial infections: effects of selective and non-selective TNF inhibitors during infection.

Garcia I, Olleros ML, Quesniaux VF, Jacobs M, Allie N, Nedospasov SA, Szymkowski DE, Ryffel B. Garcia I, et al. Among authors: szymkowski de. Adv Exp Med Biol. 2011;691:187-201. doi: 10.1007/978-1-4419-6612-4_20. Adv Exp Med Biol. 2011. PMID: 21153323 Review. No abstract available.

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Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia.

Karamita M, Barnum C, Möbius W, Tansey MG, Szymkowski DE, Lassmann H, Probert L. Karamita M, et al. Among authors: szymkowski de. JCI Insight. 2017 Apr 20;2(8):e87455. doi: 10.1172/jci.insight.87455. eCollection 2017 Apr 20. JCI Insight. 2017. PMID: 28422748 Free PMC article.

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Hippocampal TNFα Signaling Contributes to Seizure Generation in an Infection-Induced Mouse Model of Limbic Epilepsy.

Patel DC, Wallis G, Dahle EJ, McElroy PB, Thomson KE, Tesi RJ, Szymkowski DE, West PJ, Smeal RM, Patel M, Fujinami RS, White HS, Wilcox KS. Patel DC, et al. Among authors: szymkowski de. eNeuro. 2017 May 9;4(2):ENEURO.0105-17.2017. doi: 10.1523/ENEURO.0105-17.2017. eCollection 2017 Mar-Apr. eNeuro. 2017. PMID: 28497109 Free PMC article.

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MUC17, a novel membrane-tethered mucin.

Gum JR Jr, Crawley SC, Hicks JW, Szymkowski DE, Kim YS. Gum JR Jr, et al. Among authors: szymkowski de. Biochem Biophys Res Commun. 2002 Mar 1;291(3):466-75. doi: 10.1006/bbrc.2002.6475. Biochem Biophys Res Commun. 2002. PMID: 11855812

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Trypanosoma brucei growth control by TNF in mammalian host is independent of the soluble form of the cytokine.

Vanwalleghem G, Morias Y, Beschin A, Szymkowski DE, Pays E. Vanwalleghem G, et al. Among authors: szymkowski de. Sci Rep. 2017 Jul 21;7(1):6165. doi: 10.1038/s41598-017-06496-2. Sci Rep. 2017. PMID: 28733685 Free PMC article.

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Transmembrane TNF-α is sufficient for articular inflammation and hypernociception in a mouse model of gout.

Amaral FA, Bastos LF, Oliveira TH, Dias AC, Oliveira VL, Tavares LD, Costa VV, Galvão I, Soriani FM, Szymkowski DE, Ryffel B, Souza DG, Teixeira MM. Amaral FA, et al. Among authors: szymkowski de. Eur J Immunol. 2016 Jan;46(1):204-11. doi: 10.1002/eji.201545798. Epub 2015 Nov 4. Eur J Immunol. 2016. PMID: 26449770 Free article.

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