The neutrophil-NET Axis in ovarian cancer: Drivers of tumor microenvironment remodeling and therapeutic resistance.
Zendehdel H, Esgandari M, Panahinia P, Fazeli R, Etezadi A, Rahimi S.
Zendehdel H, et al.
Int Immunopharmacol. 2026 Jan 1;168(Pt 1):115826. doi: 10.1016/j.intimp.2025.115826. Epub 2025 Nov 10.
Int Immunopharmacol. 2026.
PMID: 41218585
Review.
Beyond their structural role, NETs promote immune escape by degrading chemokines essential for cytotoxic T-cell recruitment, engaging pattern-recognition receptors, and activating NF-kappaB- and STAT3-dependent pro-survival signaling in tumor and stromal cells. ...
Beyond their structural role, NETs promote immune escape by degrading chemokines essential for cytotoxic T-cell recruitment, engaging …