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Did you mean d hill a[au] (1 results)?
Efficacy and Safety of Trastuzumab Deruxtecan in Breast Cancer: A Systematic Review and Meta-Analysis.
Dowling GP, Daly GR, Keelan S, Boland F, Toomey S, Hill ADK, Hennessy BT. Dowling GP, et al. Among authors: hill adk. Clin Breast Cancer. 2023 Dec;23(8):847-855.e2. doi: 10.1016/j.clbc.2023.09.005. Epub 2023 Sep 11. Clin Breast Cancer. 2023. PMID: 37775347 Free article. Review.
Trastuzumab deruxtecan (T-DXd) is a novel antibody-drug-conjugate (ADC), primarily used in the treatment of HER2-positive breast cancer. This study aimed to conduct a systematic review to evaluate the efficacy and safety of T-DXd in treating breast cancer, based on …
Trastuzumab deruxtecan (T-DXd) is a novel antibody-drug-conjugate (ADC), primarily used in the treatment of HER2-positive breast canc …
Thymic development of gut-microbiota-specific T cells.
Zegarra-Ruiz DF, Kim DV, Norwood K, Kim M, Wu WH, Saldana-Morales FB, Hill AA, Majumdar S, Orozco S, Bell R, Round JL, Longman RS, Egawa T, Bettini ML, Diehl GE. Zegarra-Ruiz DF, et al. Among authors: hill aa. Nature. 2021 Jun;594(7863):413-417. doi: 10.1038/s41586-021-03531-1. Epub 2021 May 12. Nature. 2021. PMID: 33981034 Free PMC article.
Antigen-specific recognition of intestinal microorganisms by T cells has previously been described(3,4). Although the local environment shapes the differentiation of effector cells(3-5) it is unclear how microbiota-specific T cells are educated in the thymus. Here w …
Antigen-specific recognition of intestinal microorganisms by T cells has previously been described(3,4). Although the local environme …
Pediatric Cardiomyopathies.
Lee TM, Hsu DT, Kantor P, Towbin JA, Ware SM, Colan SD, Chung WK, Jefferies JL, Rossano JW, Castleberry CD, Addonizio LJ, Lal AK, Lamour JM, Miller EM, Thrush PT, Czachor JD, Razoky H, Hill A, Lipshultz SE. Lee TM, et al. Among authors: hill a. Circ Res. 2017 Sep 15;121(7):855-873. doi: 10.1161/CIRCRESAHA.116.309386. Circ Res. 2017. PMID: 28912187 Free PMC article. Review.
Neoadjuvant trastuzumab deruxtecan (T-DXd) with response-directed definitive therapy in early stage HER2-positive breast cancer: a phase II study protocol (SHAMROCK study).
Dowling GP, Toomey S, Bredin P, Parker I, Mulroe E, Marron J, McLoughlin O, Teiserskiene A, Power C, O'Shea AM, Greally M, Morris PG, Duke D, Hill ADK, Hennessy BT. Dowling GP, et al. Among authors: hill adk. BMC Cancer. 2024 Jan 17;24(1):91. doi: 10.1186/s12885-024-11851-4. BMC Cancer. 2024. PMID: 38233810 Free PMC article.
METHODS: This is a phase II open-label, single arm, adaptive multi-centre trial of T-DXd in the neoadjuvant setting in stage 2-3 HER2-positive breast cancer. Eligible patients will receive 5.4 mg/kg of T-DXd intravenously every 3 weeks for up to 6 cycles. ...DISCUSS …
METHODS: This is a phase II open-label, single arm, adaptive multi-centre trial of T-DXd in the neoadjuvant setting in stage 2-3 HER2 …
Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms.
Reinke S, Pantazi E, Chappell GR, Sanchez-Martinez A, Guyon R, Fergusson JR, Salman AM, Aktar A, Mukhopadhyay E, Ventura RA, Auderset F, Dubois PM, Collin N, Hill AVS, Bezbradica JS, Milicic A. Reinke S, et al. Among authors: hill avs. Cell Rep Med. 2023 Nov 21;4(11):101245. doi: 10.1016/j.xcrm.2023.101245. Epub 2023 Oct 31. Cell Rep Med. 2023. PMID: 37913775 Free PMC article.
The resulting in vivo adaptive responses have a different T(H)1/T(H)2 balance and engage divergent innate pathways while retaining high protective efficacy. ...
The resulting in vivo adaptive responses have a different T(H)1/T(H)2 balance and engage divergent innate pathways while retai …
Mathematical Models of HIV Latency.
Hill AL. Hill AL. Curr Top Microbiol Immunol. 2018;417:131-156. doi: 10.1007/82_2017_77. Curr Top Microbiol Immunol. 2018. PMID: 29164341 Free PMC article. Review.
Preliminary assessment of the efficacy of a T-cell-based influenza vaccine, MVA-NP+M1, in humans.
Lillie PJ, Berthoud TK, Powell TJ, Lambe T, Mullarkey C, Spencer AJ, Hamill M, Peng Y, Blais ME, Duncan CJ, Sheehy SH, Havelock T, Faust SN, Williams RL, Gilbert A, Oxford J, Dong T, Hill AV, Gilbert SC. Lillie PJ, et al. Among authors: hill av. Clin Infect Dis. 2012 Jul;55(1):19-25. doi: 10.1093/cid/cis327. Epub 2012 Mar 22. Clin Infect Dis. 2012. PMID: 22441650 Free PMC article. Clinical Trial.
RESULTS: Volunteers had a significantly increased T-cell response to the vaccine antigens following a single dose of the vaccine, with an increase in cytolytic effector molecules. ...CONCLUSIONS: This study provides the first demonstration of clinical efficacy of a T
RESULTS: Volunteers had a significantly increased T-cell response to the vaccine antigens following a single dose of the vaccine, wit …
A T cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+M1 in adults aged over 50 years.
Antrobus RD, Lillie PJ, Berthoud TK, Spencer AJ, McLaren JE, Ladell K, Lambe T, Milicic A, Price DA, Hill AV, Gilbert SC. Antrobus RD, et al. Among authors: hill av. PLoS One. 2012;7(10):e48322. doi: 10.1371/journal.pone.0048322. Epub 2012 Oct 31. PLoS One. 2012. PMID: 23118984 Free PMC article. Clinical Trial.
In a subset of M1-specific CD8(+) T cells, T cell receptor (TCR) gene expression was evaluated using an unbiased molecular approach. ...Increases were detected in both CD4(+) and CD8(+) T cell subsets. Clonality studies indicated that MVA-NP+M1 expanded pre-e …
In a subset of M1-specific CD8(+) T cells, T cell receptor (TCR) gene expression was evaluated using an unbiased molecular app …
A Case Report You Can't Make Up: A Bladder Foreign Body.
Winot S, Hill AC, Simon EL. Winot S, et al. Among authors: hill ac. J Emerg Med. 2021 Jul;61(1):73-75. doi: 10.1016/j.jemermed.2021.02.026. Epub 2021 May 8. J Emerg Med. 2021. PMID: 33972134 No abstract available.
The diagnostic role of T wave morphology biomarkers in congenital and acquired long QT syndrome: A systematic review.
Tardo DT, Peck M, Subbiah RN, Vandenberg JI, Hill AP. Tardo DT, et al. Among authors: hill ap. Ann Noninvasive Electrocardiol. 2023 Jan;28(1):e13015. doi: 10.1111/anec.13015. Epub 2022 Nov 7. Ann Noninvasive Electrocardiol. 2023. PMID: 36345173 Free PMC article. Review.
METHODS: Electronic databases were searched using the terms "LQTS," "long QT syndrome," "QTc prolongation," "prolonged QT," and "T wave," "T wave morphology," "T wave pattern," "T wave biomarkers." Whole text articles assessing TWM, independent of QTc, …
METHODS: Electronic databases were searched using the terms "LQTS," "long QT syndrome," "QTc prolongation," "prolonged QT," and "T wa …
2,749 results