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Year Number of Results
2007 1
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92 results

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Page 1
Perivascular space enlargement accelerates in ageing and Alzheimer's disease pathology: evidence from a three-year longitudinal multicentre study.
Menze I, Bernal J, Kaya P, Aki Ç, Pfister M, Geisendörfer J, Yakupov R, Coello RD, Valdés-Hernández MDC, Heneka MT, Brosseron F, Schmid MC, Glanz W, Incesoy EI, Butryn M, Rostamzadeh A, Meiberth D, Peters O, Preis L, Lammerding D, Gref D, Priller J, Spruth EJ, Altenstein S, Lohse A, Hetzer S, Schneider A, Fliessbach K, Kimmich O, Vogt IR, Wiltfang J, Bartels C, Schott BH, Hansen N, Dechent P, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Sanzenbacher C, Hinderer P, Scheffler K, Spottke A, Roy-Kluth N, Lüsebrink F, Neumann K, Wardlaw J, Jessen F, Schreiber S, Düzel E, Ziegler G. Menze I, et al. Alzheimers Res Ther. 2024 Oct 31;16(1):242. doi: 10.1186/s13195-024-01603-8. Alzheimers Res Ther. 2024. PMID: 39482759 Free PMC article.
Faster BG-PVS enlargement related to lower baseline white matter hyperintensities volumes (rho(spearman) = -0.17, p(FDR) = 0.001) and was more pronounced in individuals who presented with combined amyloid and tau positivity versus negativity (A + T + > A-T-, p(F …
Faster BG-PVS enlargement related to lower baseline white matter hyperintensities volumes (rho(spearman) = -0.17, p(FDR) = 0.001) and was mo …
Microglia protein profiles in CSF across Alzheimer's disease clinical stages.
Blujdea ER, van Bokhoven P, Martino-Adami PV, Marshe VS, Vromen EM, Hok-A-Hin YS, Boiten WA, Irwin DJ, Chen-Plotkin AS, Lemstra AW, Pijnenburg Y, van der Flier WM, Peters O, Hellmann-Regen J, Priller J, Schneider A, Wiltfang J, Jessen F, Düzel E, Buerger K, Perneczky R, Teipel S, Laske C, Brosseron F; DELCODE Consortium; Del Campo M, Wijdeven R, Visser PJ, Tijms BM, De Jager PL, Ramirez A, Teunissen CE, Vermunt L. Blujdea ER, et al. Nat Aging. 2026 Mar;6(3):520-533. doi: 10.1038/s43587-026-01088-0. Epub 2026 Mar 11. Nat Aging. 2026. PMID: 41814022 Free PMC article.
Cognitive reserve against Alzheimer's pathology is linked to brain activity during memory formation.
Vockert N, Machts J, Kleineidam L, Nemali A, Incesoy EI, Bernal J, Schütze H, Yakupov R, Peters O, Gref D, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Rostamzadeh A, Glanz W, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Spottke A, Roy N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Dobisch L, Dechent P, Hetzer S, Scheffler K, Zeidman P, Stern Y, Schott BH, Jessen F, Düzel E, Maass A, Ziegler G; DELCODE study group. Vockert N, et al. Nat Commun. 2024 Nov 13;15(1):9815. doi: 10.1038/s41467-024-53360-9. Nat Commun. 2024. PMID: 39537609 Free PMC article.
mTOR Signaling pathway as a master regulator of memory CD8(+) T-cells, Th17, and NK cells development and their functional properties.
Rostamzadeh D, Yousefi M, Haghshenas MR, Ahmadi M, Dolati S, Babaloo Z. Rostamzadeh D, et al. J Cell Physiol. 2019 Aug;234(8):12353-12368. doi: 10.1002/jcp.28042. Epub 2019 Feb 2. J Cell Physiol. 2019. PMID: 30710341 Review.
Researchers report that rapamycin, a selective mTOR inhibitor, and immunosuppressive agent, has surprising immunostimulatory effects on inducing both quantitative and qualitative aspects of virus-specific memory CD8(+) T-cells differentiation and homeostasis in a T- …
Researchers report that rapamycin, a selective mTOR inhibitor, and immunosuppressive agent, has surprising immunostimulatory effects on indu …
CSF biomarkers of neuroinflammation are associated with regional atrophy.
Özlü S, Dyrba M, Grazia A, Brosseron F, Buerger K, Dechent P, Düzel E, Ewers M, Fliessbach K, Glanz W, Hansen N, Hellmann-Regen J, Hetzer S, Janowitz D, Kilimann I, Kronmüller M, Laske C, Lüsebrink F, Mengel D, Perneczky R, Peters O, Priller J, Ramirez A, Rauchmann BS, Rostamzadeh A, Schneider A, Sodenkamp S, Spottke A, Spruth EJ, Synofzik M, Wiltfang J, Heneka MT, Jessen F, Teipel S. Özlü S, et al. J Neurol. 2025 Dec 24;273(1):46. doi: 10.1007/s00415-025-13564-5. J Neurol. 2025. PMID: 41442069 Free PMC article.
Regional atrophy rates were estimated using linear mixed-effects models including biomarker time, A/T classification, diagnosis, and covariates (age, sex, education, ApoE-epsilon4). Individual slopes were then entered into mediation models. ...Mediation analyses revealed …
Regional atrophy rates were estimated using linear mixed-effects models including biomarker time, A/T classification, diagnosis, an …
Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition.
Hayek D, Ziegler G, Kleineidam L, Brosseron F, Nemali A, Vockert N, Ravichandran KA, Betts MJ, Peters O, Schneider LS, Wang X, Priller J, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Bartels C, Rostamzadeh A, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Laske C, Mengel D, Synofzik M, Munk MH, Spottke A, Roy N, Roeske S, Kuhn E, Ramirez A, Dobisch L, Schmid M, Berger M, Wolfsgruber S, Yakupov R, Hetzer S, Dechent P, Ewers M, Scheffler K, Schott BH, Schreiber S, Orellana A, de Rojas I, Marquié M, Boada M, Sotolongo O, González PG, Puerta R, Düzel E, Jessen F, Wagner M, Ruiz A, Heneka MT, Maass A. Hayek D, et al. Mol Psychiatry. 2024 Apr;29(4):992-1004. doi: 10.1038/s41380-023-02387-3. Epub 2024 Jan 12. Mol Psychiatry. 2024. PMID: 38216727 Free PMC article.
Biomarker disclosure protocols in prodromal Alzheimer's disease clinical trials.
Rahman-Filipiak A, Bolton C, Grill JD, Rostamzadeh A, Chin N, Heidebrink J, Getz S, Fowler NR, Rosen A, Lingler J, Wijsman E, Clark L; Advisory Group on Risk Evidence Education in Dementia (AGREED). Rahman-Filipiak A, et al. Alzheimers Dement. 2023 Sep;19(9):4270-4275. doi: 10.1002/alz.13380. Epub 2023 Jul 14. Alzheimers Dement. 2023. PMID: 37450489 Free PMC article. Review.
Altered frequency of CD8(+) CD11c(+) T cells and expression of immunosuppressive molecules in lymphoid organs of mouse model of colorectal cancer.
Rostamzadeh D, Haghshenas MR, Daryanoosh F, Samadi M, Hosseini A, Ghaderi A, Mojtahedi Z, Babaloo Z. Rostamzadeh D, et al. J Cell Physiol. 2019 Jul;234(7):11986-11998. doi: 10.1002/jcp.27856. Epub 2019 Jan 8. J Cell Physiol. 2019. PMID: 30623416
Recent reports identify CD11c-expressing CD8(+) T cells as a new subset of CD8(+) regulatory T cells (Treg). Evidence exists that CD11c(+) CD8(+) T cells may exert their effector or regulatory functions under different conditions. ...Here, we have assessed CD …
Recent reports identify CD11c-expressing CD8(+) T cells as a new subset of CD8(+) regulatory T cells (Treg). Evidence exists t …
Joint trajectories of brain atrophy, white matter hyperintensities and cognition quantify brain maintenance.
Menze I, Bernal J, Kievit RA, Tripathi KP, Kaleck T, Yakupov R, Altenstein S, Bartels C, Buerger K, Butryn M, Dechent P, Ewers M, Fliessbach K, Frommann I, Gemenetzi M, Glanz W, Gref D, Hellmann-Regen J, Hetzer S, Incesoy EI, Janowitz D, Kiliman I, Kleineidam L, Kronmüller MT, Laske C, van Lent DM, Lüsebrink F, Perneczky R, Peters O, Preis L, Priller J, Rauchmann BS, Rostamzadeh A, Roeske S, Scheffler K, Schott BH, Schneider A, Sodenkamp S, Spottke A, Spruth EJ, Stark M, Teipel S, Wagner M, Wiltfang J, Jessen F, Ramirez A, Schreiber S, Düzel E, Ziegler G. Menze I, et al. Nat Commun. 2026 Jul 4;17(1):5846. doi: 10.1038/s41467-026-74957-2. Nat Commun. 2026. PMID: 42401584 Free PMC article.
92 results