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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 2
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328 results

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Page 1
An autoimmune stem-like CD8 T cell population drives type 1 diabetes.
Gearty SV, Dündar F, Zumbo P, Espinosa-Carrasco G, Shakiba M, Sanchez-Rivera FJ, Socci ND, Trivedi P, Lowe SW, Lauer P, Mohibullah N, Viale A, DiLorenzo TP, Betel D, Schietinger A. Gearty SV, et al. Nature. 2022 Feb;602(7895):156-161. doi: 10.1038/s41586-021-04248-x. Epub 2021 Nov 30. Nature. 2022. PMID: 34847567 Free PMC article.
CD8 T cell-mediated autoimmune diseases result from the breakdown of self-tolerance mechanisms in autoreactive CD8 T cells(1). How autoimmune T cell populations arise and are sustained, and the molecular programmes defining the autoimmune T cell state, …
CD8 T cell-mediated autoimmune diseases result from the breakdown of self-tolerance mechanisms in autoreactive CD8 T cells(1). …
TOX is a critical regulator of tumour-specific T cell differentiation.
Scott AC, Dündar F, Zumbo P, Chandran SS, Klebanoff CA, Shakiba M, Trivedi P, Menocal L, Appleby H, Camara S, Zamarin D, Walther T, Snyder A, Femia MR, Comen EA, Wen HY, Hellmann MD, Anandasabapathy N, Liu Y, Altorki NK, Lauer P, Levy O, Glickman MS, Kaye J, Betel D, Philip M, Schietinger A. Scott AC, et al. Nature. 2019 Jul;571(7764):270-274. doi: 10.1038/s41586-019-1324-y. Epub 2019 Jun 17. Nature. 2019. PMID: 31207604 Free PMC article.
Tumour-specific CD8 T cell dysfunction is a differentiation state that is distinct from the functional effector or memory T cell states(1-6). ...Expression of TOX is driven by chronic T cell receptor stimulation and NFAT activation. Ectopic expression of TOX …
Tumour-specific CD8 T cell dysfunction is a differentiation state that is distinct from the functional effector or memory T ce …
Hallmarks of CD8(+) T cell dysfunction are established within hours of tumor antigen encounter before cell division.
Rudloff MW, Zumbo P, Favret NR, Roetman JJ, Detrés Román CR, Erwin MM, Murray KA, Jonnakuti ST, Dündar F, Betel D, Philip M. Rudloff MW, et al. Nat Immunol. 2023 Sep;24(9):1527-1539. doi: 10.1038/s41590-023-01578-y. Epub 2023 Aug 3. Nat Immunol. 2023. PMID: 37537361 Free PMC article.
Tumor-specific CD8+ T cells (TST) in patients with cancer are dysfunctional and unable to halt cancer progression. TST dysfunction, also known as exhaustion, is thought to be driven by chronic T cell antigen receptor (TCR) stimulation over days to weeks. However, we …
Tumor-specific CD8+ T cells (TST) in patients with cancer are dysfunctional and unable to halt cancer progression. TST dysfunction, a …
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion.
Shakiba M, Zumbo P, Espinosa-Carrasco G, Menocal L, Dündar F, Carson SE, Bruno EM, Sanchez-Rivera FJ, Lowe SW, Camara S, Koche RP, Reuter VP, Socci ND, Whitlock B, Tamzalit F, Huse M, Hellmann MD, Wells DK, Defranoux NA, Betel D, Philip M, Schietinger A. Shakiba M, et al. J Exp Med. 2022 Feb 7;219(2):e20201966. doi: 10.1084/jem.20201966. Epub 2021 Dec 22. J Exp Med. 2022. PMID: 34935874 Free PMC article.
T cell receptor (TCR) signal strength is a key determinant of T cell responses. We developed a cancer mouse model in which tumor-specific CD8 T cells (TST cells) encounter tumor antigens with varying TCR signal strength. ...Our study defines the role of TCR s …
T cell receptor (TCR) signal strength is a key determinant of T cell responses. We developed a cancer mouse model in which tum …
Expression of Concern.
Listed NA. Listed NA. Eur Rev Med Pharmacol Sci. 2024 Jan;28(2):445. doi: 10.26355/eurrev_202401_35160. Eur Rev Med Pharmacol Sci. 2024. PMID: 38305629 Free article.
DOI: 10.26355/eurrev_202312_34697-PMID: 38112953. . M.C. Medori, K. Donato, L. Stuppia, T. Beccari, M. Dundar, R.S. Marks, S. Michelini, E. Borghetti, C. Zuccato, L. Seppilli, H. ...Medori, A. Macchia, S. Cecchin, M.R. Ceccarini, T. Beccari, V. Gatta, L. …
DOI: 10.26355/eurrev_202312_34697-PMID: 38112953. . M.C. Medori, K. Donato, L. Stuppia, T. Beccari, M. Dundar, R.S. Marks …
Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Chandran SS, Ma J, Klatt MG, Dündar F, Bandlamudi C, Razavi P, Wen HY, Weigelt B, Zumbo P, Fu SN, Banks LB, Yi F, Vercher E, Etxeberria I, Bestman WD, Da Cruz Paula A, Aricescu IS, Drilon A, Betel D, Scheinberg DA, Baker BM, Klebanoff CA. Chandran SS, et al. Nat Med. 2022 May;28(5):946-957. doi: 10.1038/s41591-022-01786-3. Epub 2022 Apr 28. Nat Med. 2022. PMID: 35484264 Free PMC article.
Here we describe a high-throughput platform combining single-cell transcriptomic and T cell receptor (TCR) sequencing to establish whether mutant PIK3CA, among the most frequently genomically altered driver oncogenes, generates an immunogenic public NeoAg. ...Finally, adop …
Here we describe a high-throughput platform combining single-cell transcriptomic and T cell receptor (TCR) sequencing to establish wh …
A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes.
Rubio-Navarro A, Gómez-Banoy N, Stoll L, Dündar F, Mawla AM, Ma L, Cortada E, Zumbo P, Li A, Reiterer M, Montoya-Oviedo N, Homan EA, Imai N, Gilani A, Liu C, Naji A, Yang B, Chong ACN, Cohen DE, Chen S, Cao J, Pitt GS, Huising MO, Betel D, Lo JC. Rubio-Navarro A, et al. Nat Cell Biol. 2023 Apr;25(4):565-578. doi: 10.1038/s41556-023-01103-1. Epub 2023 Mar 16. Nat Cell Biol. 2023. PMID: 36928765 Free PMC article.
Sequential appetite suppression by oral and visceral feedback to the brainstem.
Ly T, Oh JY, Sivakumar N, Shehata S, La Santa Medina N, Huang H, Liu Z, Fang W, Barnes C, Dundar N, Jarvie BC, Ravi A, Barnhill OK, Li C, Lee GR, Choi J, Jang H, Knight ZA. Ly T, et al. Nature. 2023 Dec;624(7990):130-137. doi: 10.1038/s41586-023-06758-2. Epub 2023 Nov 22. Nature. 2023. PMID: 37993711 Free PMC article.
Providing care for older adults in the Emergency Department: expert clinical recommendations from the European Task Force on Geriatric Emergency Medicine.
Lucke JA, Mooijaart SP, Heeren P, Singler K, McNamara R, Gilbert T, Nickel CH, Castejon S, Mitchell A, Mezera V, Van der Linden L, Lim SE, Thaur A, Karamercan MA, Blomaard LC, Dundar ZD, Chueng KY, Islam F, de Groot B, Conroy S. Lucke JA, et al. Eur Geriatr Med. 2022 Apr;13(2):309-317. doi: 10.1007/s41999-021-00578-1. Epub 2021 Nov 5. Eur Geriatr Med. 2022. PMID: 34738224 Free PMC article. Review.
328 results