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Impact of immunizations on the disease burden of American Indian and Alaska native children.
Singleton R, Holve S, Groom A, McMahon BJ, Santosham M, Brenneman G, O'Brien KL. Singleton R, et al. Arch Pediatr Adolesc Med. 2009 May;163(5):446-53. doi: 10.1001/archpediatrics.2009.44. Arch Pediatr Adolesc Med. 2009. PMID: 19414691 Review.
As recently as 25 years ago, rates of hepatitis A and B virus, Haemophilus influenzae type b, and Streptococcus pneumoniae infections were as much as 10 times higher among AI/AN children compared with the general US child population. In the past quarter century, rou …
As recently as 25 years ago, rates of hepatitis A and B virus, Haemophilus influenzae type b, and Streptococcus pneumoniae inf …
Combined c-Met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma.
Olmez I, Zhang Y, Manigat L, Benamar M, Brenneman B, Nakano I, Godlewski J, Bronisz A, Lee J, Abbas T, Abounader R, Purow B. Olmez I, et al. Cancer Res. 2018 Aug 1;78(15):4360-4369. doi: 10.1158/0008-5472.CAN-17-3124. Epub 2018 May 29. Cancer Res. 2018. PMID: 29844123 Free PMC article.
Using a phospho-RTK protein array, we found that both c-Met and TrkA-B pathways were significantly activated upon CDK4/6 inhibition in GBM cells. We therefore investigated the efficacy of combined CDK4/6 and c-Met/TrkA-B inhibition against GBM. We show that both c-M …
Using a phospho-RTK protein array, we found that both c-Met and TrkA-B pathways were significantly activated upon CDK4/6 inhibition i …
BAFF Induces Tertiary Lymphoid Structures and Positions T Cells within the Glomeruli during Lupus Nephritis.
Kang S, Fedoriw Y, Brenneman EK, Truong YK, Kikly K, Vilen BJ. Kang S, et al. J Immunol. 2017 Apr 1;198(7):2602-2611. doi: 10.4049/jimmunol.1600281. Epub 2017 Feb 24. J Immunol. 2017. PMID: 28235864 Free PMC article.
Mechanistically, lowering BAFF levels also diminished the number of T cells positioned inside the glomeruli and reduced inflammation. Thus, BAFF plays a previously unappreciated role in lupus nephritis by inducing renal TLSs and regulating the position of T cells wi …
Mechanistically, lowering BAFF levels also diminished the number of T cells positioned inside the glomeruli and reduced inflammation. …
Case-cohort analysis of case-coverage studies of vaccine effectiveness.
Moulton LH, Wolff MC, Brenneman G, Santosham M. Moulton LH, et al. Am J Epidemiol. 1995 Nov 1;142(9):1000-6. doi: 10.1093/oxfordjournals.aje.a117730. Am J Epidemiol. 1995. PMID: 7572966
The case-cohort analytic approach is illustrated with data from studies of a vaccine for Haemophilus influenzae type b (Hib) disease in children living on a southwestern Native American reservation during 1988-1993....
The case-cohort analytic approach is illustrated with data from studies of a vaccine for Haemophilus influenzae type b (Hib) disease …
First Report of Bacterial Blight of Sugar Beet Caused by Pseudomonas syringae pv. aptata in Georgia, USA.
Dutta B, Ingram T, Gitaitis RD, Langston DB, Brenneman T, Webster TM, Davis RF. Dutta B, et al. Plant Dis. 2014 Oct;98(10):1423. doi: 10.1094/PDIS-03-14-0235-PDN. Plant Dis. 2014. PMID: 30703981
Sugar beet (Beta vulgaris L.) is not currently a commercial crop in Georgia, but experimental plantings as a winter rotational crop are promising in terms of yield and industrial sugar production (T. Brenneman, personal communication). A disease outbreak of suspecte …
Sugar beet (Beta vulgaris L.) is not currently a commercial crop in Georgia, but experimental plantings as a winter rotational crop are prom …
The Novel, Clinical-Stage Soluble Guanylate Cyclase Activator BI 685509 Protects from Disease Progression in Models of Renal Injury and Disease.
Reinhart GA, Harrison PC, Lincoln K, Chen H, Sun P, Hill J, Qian HS, McHugh MC, Clifford H, Ng KJ, Wang H, Fowler D, Gueneva-Boucheva K, Brenneman JB, Bosanac T, Wong D, Fryer RM, Sarko C, Boustany-Kari CM, Pullen SS. Reinhart GA, et al. J Pharmacol Exp Ther. 2023 Mar;384(3):382-392. doi: 10.1124/jpet.122.001423. Epub 2022 Dec 6. J Pharmacol Exp Ther. 2023. PMID: 36507845
Limited efficacy of a Haemophilus influenzae type b conjugate vaccine in Alaska Native infants. The Alaska H. influenzae Vaccine Study Group.
Ward J, Brenneman G, Letson GW, Heyward WL. Ward J, et al. N Engl J Med. 1990 Nov 15;323(20):1393-401. doi: 10.1056/NEJM199011153232006. N Engl J Med. 1990. PMID: 2233906 Free article. Clinical Trial.
BACKGROUND: The prevention of invasive Haemophilus influenzae type b disease requires a vaccine that is effective when administered during the first six months of life. The infants of Alaska Natives are at particularly high risk of invasive H. influenzae type b dise …
BACKGROUND: The prevention of invasive Haemophilus influenzae type b disease requires a vaccine that is effective when administered d …
Blood alcohol levels for American Indian mothers and newborns.
Kvigne VL, Randall B, Simanton EG, Brenneman G, Welty TK. Kvigne VL, et al. Pediatrics. 2012 Oct;130(4):e1015-8. doi: 10.1542/peds.2011-1400. Epub 2012 Sep 10. Pediatrics. 2012. PMID: 22966030
Sixty minutes after delivery, the blood alcohol level for this newborn was 39.5 mg/dL, and the alcohol level of the mother was 42.1 mg/dL. Newborn B1 of mother B had FAS. At 67 minutes after birth, newborn B1 had a blood alcohol level of 246.5 mg/dL, which dropped to 178.7 …
Sixty minutes after delivery, the blood alcohol level for this newborn was 39.5 mg/dL, and the alcohol level of the mother was 42.1 mg/dL. N …
Soluble CD200 is critical to engraft chronic lymphocytic leukemia cells in immunocompromised mice.
Wong KK, Brenneman F, Chesney A, Spaner DE, Gorczynski RM. Wong KK, et al. Cancer Res. 2012 Oct 1;72(19):4931-43. doi: 10.1158/0008-5472.CAN-12-1390. Epub 2012 Aug 8. Cancer Res. 2012. PMID: 22875025
Engraftment of CLL cells did not occur after infusion of CLL plasma depleted of sCD200 and was abolished in mice treated with anti-CD200 or OKT3 monoclonal antibody (mAb), suggesting a role for both sCD200 and T cells in CLL engraftment. Notably, anti-CD200 mAb was as effe …
Engraftment of CLL cells did not occur after infusion of CLL plasma depleted of sCD200 and was abolished in mice treated with anti-CD200 or …
A new high affinity technetium-99m-bombesin analogue with low abdominal accumulation.
Lin KS, Luu A, Baidoo KE, Hashemzadeh-Gargari H, Chen MK, Brenneman K, Pili R, Pomper M, Carducci MA, Wagner HN Jr. Lin KS, et al. Bioconjug Chem. 2005 Jan-Feb;16(1):43-50. doi: 10.1021/bc049820h. Bioconjug Chem. 2005. PMID: 15656574
The uptake in the pancreas could be blocked by BN, partially blocked by neuromedin B, but not affected by somatostatin, indicating that the in vivo binding was BN/GRP receptor specific. ...
The uptake in the pancreas could be blocked by BN, partially blocked by neuromedin B, but not affected by somatostatin, indicating th …
21 results