Polyphenols-Based Nanosheets of Propolis Modulate Cytotoxic Amyloid Fibril Assembly of α-Synuclein.
Rafiei Y, Salmani B, Mirzaei-Behbahani B, Taleb M, Meratan AA, Ramezani M, Nikfarjam N, Becker S, Rezaei-Ghaleh N.
Rafiei Y, et al.
ACS Chem Neurosci. 2022 Nov 16;13(22):3168-3179. doi: 10.1021/acschemneuro.2c00465. Epub 2022 Oct 31.
ACS Chem Neurosci. 2022.
PMID: 36314062
Based on a range of biophysical data including intrinsic and extrinsic fluorescence, circular dichroism (CD) data, and nuclear magnetic resonance spectroscopy, we propose a model for the interaction of alpha-syn with PFP nanosheets, where the positively charged N-terminal and the …
Based on a range of biophysical data including intrinsic and extrinsic fluorescence, circular dichroism (CD) data, and nuclear magnetic reso …