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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1964 1
1965 1
1966 1
1968 4
1971 5
1972 2
1973 2
1974 2
1975 8
1976 11
1977 3
1978 15
1979 16
1980 15
1981 27
1982 45
1983 44
1984 46
1985 42
1986 48
1987 90
1988 136
1989 144
1990 172
1991 186
1992 206
1993 235
1994 274
1995 306
1996 312
1997 331
1998 419
1999 502
2000 583
2001 759
2002 953
2003 1161
2004 1379
2005 1579
2006 1708
2007 2019
2008 2286
2009 2540
2010 3127
2011 3721
2012 4234
2013 5503
2014 8575
2015 11172
2016 11262
2017 11415
2018 14636
2019 17892
2020 21437
2021 22819
2022 122
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138,130 results
Results by year
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Page 1
The Frequency of Ras Mutations in Cancer.
Prior IA, Hood FE, Hartley JL. Prior IA, et al. Cancer Res. 2020 Jul 15;80(14):2969-2974. doi: 10.1158/0008-5472.CAN-19-3682. Epub 2020 Mar 24. Cancer Res. 2020. PMID: 32209560 Free PMC article. Review.
Ras is frequently mutated in cancer, however, there is a lack of consensus in the literature regarding the cancer mutation frequency of Ras, with quoted values varying from 10%-30%. ...These percentages were then applied to current U.S. cancer incidenc …
Ras is frequently mutated in cancer, however, there is a lack of consensus in the literature regarding the cancer mutation fre …
M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer.
Lan J, Sun L, Xu F, Liu L, Hu F, Song D, Hou Z, Wu W, Luo X, Wang J, Yuan X, Hu J, Wang G. Lan J, et al. Cancer Res. 2019 Jan 1;79(1):146-158. doi: 10.1158/0008-5472.CAN-18-0014. Epub 2018 Nov 6. Cancer Res. 2019. PMID: 30401711 Free article.
Mechanistically, miR-21-5p and miR-155-5p were transferred to colorectal cancer cells by MDE and bound to the BRG1 coding sequence, downregulating expression of BRG1, which has been identified as a key factor promoting the colorectal cancer metastasis, yet is downre …
Mechanistically, miR-21-5p and miR-155-5p were transferred to colorectal cancer cells by MDE and bound to the BRG1 coding sequence, d …
CRISPR-Cas13 Precision Transcriptome Engineering in Cancer.
Granados-Riveron JT, Aquino-Jarquin G. Granados-Riveron JT, et al. Cancer Res. 2018 Aug 1;78(15):4107-4113. doi: 10.1158/0008-5472.CAN-18-0785. Epub 2018 Jul 18. Cancer Res. 2018. PMID: 30021724 Free article. Review.
All of these properties give us a glimpse about the potential of the CRISPR toolkit for precise transcriptome engineering, possibly leading to an expansion of CRISPR technologies for cancer therapeutics and diagnostics. Here, we examine previously unaddressed aspect …
All of these properties give us a glimpse about the potential of the CRISPR toolkit for precise transcriptome engineering, possibly leading …
Genomic Instability in Cancer: Teetering on the Limit of Tolerance.
Andor N, Maley CC, Ji HP. Andor N, et al. Cancer Res. 2017 May 1;77(9):2179-2185. doi: 10.1158/0008-5472.CAN-16-1553. Epub 2017 Apr 21. Cancer Res. 2017. PMID: 28432052 Free PMC article. Review.
Herein, we explore the possibility that a high genomic instability could be the basis for a tumor's sensitivity to DNA-damaging therapies. We primarily focus on studies of epithelial-derived solid tumors. Cancer Res; 77(9); 2179-85. 2017 AACR....
Herein, we explore the possibility that a high genomic instability could be the basis for a tumor's sensitivity to DNA-damaging thera …
Single-Cell Sequencing for Precise Cancer Research: Progress and Prospects.
Zhang X, Marjani SL, Hu Z, Weissman SM, Pan X, Wu S. Zhang X, et al. Cancer Res. 2016 Mar 15;76(6):1305-12. doi: 10.1158/0008-5472.CAN-15-1907. Epub 2016 Mar 3. Cancer Res. 2016. PMID: 26941284 Free article. Review.
Advances in genomic technology have enabled the faithful detection and measurement of mutations and the gene expression profile of cancer cells at the single-cell level. ...Here, we discuss the current methods for single cancer-cell sequencing, with a strong …
Advances in genomic technology have enabled the faithful detection and measurement of mutations and the gene expression profile of …
Emerging Role of CRISPR/Cas9 Technology for MicroRNAs Editing in Cancer Research.
Aquino-Jarquin G. Aquino-Jarquin G. Cancer Res. 2017 Dec 15;77(24):6812-6817. doi: 10.1158/0008-5472.CAN-17-2142. Epub 2017 Dec 5. Cancer Res. 2017. PMID: 29208606 Free article. Review.
MicroRNAs (miRNA) are small, noncoding RNA molecules with a master role in the regulation of important tasks in different critical processes of cancer pathogenesis. Because there are different miRNAs implicated in all the stages of cancer, for example, functioning a …
MicroRNAs (miRNA) are small, noncoding RNA molecules with a master role in the regulation of important tasks in different critical processes …
Cancer Cell-Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma.
Tian C, Öhlund D, Rickelt S, Lidström T, Huang Y, Hao L, Zhao RT, Franklin O, Bhatia SN, Tuveson DA, Hynes RO. Tian C, et al. Cancer Res. 2020 Apr 1;80(7):1461-1474. doi: 10.1158/0008-5472.CAN-19-2578. Epub 2020 Feb 6. Cancer Res. 2020. PMID: 32029550 Free PMC article.
All three genes were associated with a poor prognosis in human patients and high levels of SERPINB5, secreted by cancer cells and deposited in the ECM, correlated with poor patient prognosis. This study provides strong evidence that cancer cell-derived matrisome pro …
All three genes were associated with a poor prognosis in human patients and high levels of SERPINB5, secreted by cancer cells and dep …
Computational Radiomics System to Decode the Radiographic Phenotype.
van Griethuysen JJM, Fedorov A, Parmar C, Hosny A, Aucoin N, Narayan V, Beets-Tan RGH, Fillion-Robin JC, Pieper S, Aerts HJWL. van Griethuysen JJM, et al. Cancer Res. 2017 Nov 1;77(21):e104-e107. doi: 10.1158/0008-5472.CAN-17-0339. Cancer Res. 2017. PMID: 29092951 Free PMC article.
Radiomics aims to quantify phenotypic characteristics on medical imaging through the use of automated algorithms. Radiomic artificial intelligence (AI) technology, either based on engineered hard-coded algorithms or deep learning methods, can be used to develop noninvasive …
Radiomics aims to quantify phenotypic characteristics on medical imaging through the use of automated algorithms. Radiomic artificial intell …
ERK1/2 Signaling Induces Upregulation of ANGPT2 and CXCR4 to Mediate Liver Metastasis in Colon Cancer.
Urosevic J, Blasco MT, Llorente A, Bellmunt A, Berenguer-Llergo A, Guiu M, Cañellas A, Fernandez E, Burkov I, Clapés M, Cartanà M, Figueras-Puig C, Batlle E, Nebreda AR, Gomis RR. Urosevic J, et al. Cancer Res. 2020 Nov 1;80(21):4668-4680. doi: 10.1158/0008-5472.CAN-19-4028. Epub 2020 Aug 19. Cancer Res. 2020. PMID: 32816905 Free article.
Carcinoma development in colorectal cancer is driven by genetic alterations in numerous signaling pathways. Alterations in the RAS-ERK1/2 pathway are associated with the shortest overall survival for patients after diagnosis of colorectal cancer metastatic disease, …
Carcinoma development in colorectal cancer is driven by genetic alterations in numerous signaling pathways. Alterations in the RAS-ER …
Spatially Resolved Transcriptomics Enables Dissection of Genetic Heterogeneity in Stage III Cutaneous Malignant Melanoma.
Thrane K, Eriksson H, Maaskola J, Hansson J, Lundeberg J. Thrane K, et al. Cancer Res. 2018 Oct 15;78(20):5970-5979. doi: 10.1158/0008-5472.CAN-18-0747. Epub 2018 Aug 28. Cancer Res. 2018. PMID: 30154148 Free article.
Further insights into the mechanisms underlying melanoma are crucial for understanding tumor progression and responses to treatment. Here we adapted the technology of spatial transcriptomics (ST) to melanoma lymph node biopsies and successfully sequenced the transcriptomes …
Further insights into the mechanisms underlying melanoma are crucial for understanding tumor progression and responses to treatment. Here we …
138,130 results
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