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Cell-Selective Adeno-Associated Virus-Mediated SCN1A Gene Regulation Therapy Rescues Mortality and Seizure Phenotypes in a Dravet Syndrome Mouse Model and Is Well Tolerated in Nonhuman Primates.
Tanenhaus A, Stowe T, Young A, McLaughlin J, Aeran R, Lin IW, Li J, Hosur R, Chen M, Leedy J, Chou T, Pillay S, Vila MC, Kearney JA, Moorhead M, Belle A, Tagliatela S. Tanenhaus A, et al. Among authors: tagliatela s. Hum Gene Ther. 2022 Jun;33(11-12):579-597. doi: 10.1089/hum.2022.037. Hum Gene Ther. 2022. PMID: 35435735 Free PMC article.
Long-term seizure suppression and optogenetic analyses of synaptic connectivity in epileptic mice with hippocampal grafts of GABAergic interneurons.
Henderson KW, Gupta J, Tagliatela S, Litvina E, Zheng X, Van Zandt MA, Woods N, Grund E, Lin D, Royston S, Yanagawa Y, Aaron GB, Naegele JR. Henderson KW, et al. Among authors: tagliatela s. J Neurosci. 2014 Oct 1;34(40):13492-504. doi: 10.1523/JNEUROSCI.0005-14.2014. J Neurosci. 2014. PMID: 25274826 Free PMC article.