Species differences between rats and primates (humans and monkeys) in complex cleavage pathways of DS-8500a characterized by 14C-ADME studies in humans and monkeys after administration of two radiolabeled compounds and in vitro studies.
Drug Metab Pharmacokinet. 2022 Aug;45:100459. doi: 10.1016/j.dmpk.2022.100459. Epub 2022 Mar 19.
Drug Metab Pharmacokinet. 2022.
PMID: 35716472