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Year Number of Results
1966 1
2007 1
2010 1
2012 3
2013 1
2014 2
2015 3
2016 3
2017 1
2018 2
2021 0
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16 results
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Page 1
Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.
Sudom A, Talreja S, Danao J, Bragg E, Kegel R, Min X, Richardson J, Zhang Z, Sharkov N, Marcora E, Thibault S, Bradley J, Wood S, Lim AC, Chen H, Wang S, Foltz IN, Sambashivan S, Wang Z. Sudom A, et al. Among authors: talreja s. J Biol Chem. 2018 Aug 10;293(32):12634-12646. doi: 10.1074/jbc.RA118.002352. Epub 2018 May 24. J Biol Chem. 2018. PMID: 29794134 Free PMC article.
TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer's disease variant Trem2R47H on murine myeloid cell function.
Cheng Q, Danao J, Talreja S, Wen P, Yin J, Sun N, Li CM, Chui D, Tran D, Koirala S, Chen H, Foltz IN, Wang S, Sambashivan S. Cheng Q, et al. Among authors: talreja s. J Biol Chem. 2018 Aug 10;293(32):12620-12633. doi: 10.1074/jbc.RA118.001848. Epub 2018 Mar 29. J Biol Chem. 2018. PMID: 29599291 Free PMC article.
Tubulocystic Renal Cell Carcinoma: A Great Imitator.
Banerjee I, Yadav SS, Tomar V, Yadav S, Talreja S. Banerjee I, et al. Among authors: talreja s. Rev Urol. 2016;18(2):118-21. doi: 10.3909/riu0692. Rev Urol. 2016. PMID: 27601972 Free PMC article.
AMG 580: a novel small molecule phosphodiesterase 10A (PDE10A) positron emission tomography tracer.
Chen H, Lester-Zeiner D, Shi J, Miller S, Glaus C, Hu E, Chen N, Able J, Biorn C, Wong J, Ma J, Michelsen K, Hill Della Puppa G, Kazules T, Dou HH, Talreja S, Zhao X, Chen A, Rumfelt S, Kunz RK, Ye H, Thiel OR, Williamson T, Davis C, Porter A, Immke D, Allen JR, Treanor J. Chen H, et al. Among authors: talreja s. J Pharmacol Exp Ther. 2015 Feb;352(2):327-37. doi: 10.1124/jpet.114.220517. Epub 2014 Dec 11. J Pharmacol Exp Ther. 2015. PMID: 25502803
Discovery of clinical candidate 1-(4-(3-(4-(1H-benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone (AMG 579), a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A).
Hu E, Chen N, Bourbeau MP, Harrington PE, Biswas K, Kunz RK, Andrews KL, Chmait S, Zhao X, Davis C, Ma J, Shi J, Lester-Zeiner D, Danao J, Able J, Cueva M, Talreja S, Kornecook T, Chen H, Porter A, Hungate R, Treanor J, Allen JR. Hu E, et al. Among authors: talreja s. J Med Chem. 2014 Aug 14;57(15):6632-41. doi: 10.1021/jm500713j. Epub 2014 Aug 4. J Med Chem. 2014. PMID: 25062128
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