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31 results

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Page 1
Long Noncoding RNA lnc-TCEA1-3 Affects Osteoclastic Function by Regulating ATP6V1H.
Hou Y, Yang S, Zhao Z, Huang Y, Zhang Y, Ruan W, Duan X. Hou Y, et al. Crit Rev Eukaryot Gene Expr. 2024;34(1):15-26. doi: 10.1615/CritRevEukaryotGeneExpr.2023048669. Crit Rev Eukaryot Gene Expr. 2024. PMID: 37824389
In this study, we found that the above four SNPs were located at lncRNA lnc-TCEA1-3 by using bioinformatics analysis. We further detected the function of lnc-TCEA1-3 on regulating ATP6V1H and osteoclast function using Atp6v1h knockout mice, lentivirus transfection a …
In this study, we found that the above four SNPs were located at lncRNA lnc-TCEA1-3 by using bioinformatics analysis. We further dete …
TCEA1 regulates the proliferative potential of mouse myeloid cells.
Yang T, Cui H, Wen M, Zuber J, Kogan SC, Wei G. Yang T, et al. Exp Cell Res. 2018 Sep 15;370(2):551-560. doi: 10.1016/j.yexcr.2018.07.020. Epub 2018 Jul 25. Exp Cell Res. 2018. PMID: 30009791 Free PMC article.
Knocking down the expression of Tcea1 in the 32Dcl3 myeloid cell line led to enhanced proliferation of myeloid cells and blockage of myeloid differentiation induced by G-CSF. In addition, silence of Tcea1 inhibited apoptosis of myeloid cells. Thus, Tcea1 was …
Knocking down the expression of Tcea1 in the 32Dcl3 myeloid cell line led to enhanced proliferation of myeloid cells and blockage of …
TCEA1 Suppresses Acute Promyelocytic Leukemia by Upregulating C/EBPepsilon and IRF8.
Yang T, Wan Y, Chu C, Chen X. Yang T, et al. Int J Mol Sci. 2026 Jun 15;27(12):5380. doi: 10.3390/ijms27125380. Int J Mol Sci. 2026. PMID: 42353099 Free PMC article.
Mechanistically, TCEA1 overexpression upregulated C/EBPepsilon and IRF8 at the mRNA and protein levels; conversely, TCEA1 knockdown downregulated both. ...Analysis of public APL datasets revealed that high TCEA1 expression is associated with a favorable progn …
Mechanistically, TCEA1 overexpression upregulated C/EBPepsilon and IRF8 at the mRNA and protein levels; conversely, TCEA1 knoc …
Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence.
Siametis A, Stratigi K, Giamaki D, Chatzinikolaou G, Akalestou-Clocher A, Goulielmaki E, Luke B, Schumacher B, Garinis GA. Siametis A, et al. Nat Commun. 2024 May 14;15(1):4061. doi: 10.1038/s41467-024-48443-6. Nat Commun. 2024. PMID: 38744897 Free PMC article.
Transcription stress has been linked to DNA damage -driven aging, yet the underlying mechanism remains unclear. Here, we demonstrate that Tcea1(-/-) cells, which harbor a TFIIS defect in transcription elongation, exhibit RNAPII stalling at oxidative DNA damage sites, impai …
Transcription stress has been linked to DNA damage -driven aging, yet the underlying mechanism remains unclear. Here, we demonstrate that …
Gene structure and chromosome mapping of mouse transcription elongation factor S-II (Tcea1).
Ito T, Seldin MF, Taketo MM, Kubo T, Natori S. Ito T, et al. Gene. 2000 Feb 22;244(1-2):55-63. doi: 10.1016/s0378-1119(00)00007-x. Gene. 2000. PMID: 10689187
We also identified a processed pseudogene (Tcea1-ps1) with a sequence highly homologous to those of S-II cDNAs but containing a translation termination codon within its open reading frame. Linkage analysis showed that Tcea1 and Tcea1-ps1 are mapped on mouse c …
We also identified a processed pseudogene (Tcea1-ps1) with a sequence highly homologous to those of S-II cDNAs but containing a trans …
CHCHD7-PLAG1 and TCEA1-PLAG1 gene fusions resulting from cryptic, intrachromosomal 8q rearrangements in pleomorphic salivary gland adenomas.
Asp J, Persson F, Kost-Alimova M, Stenman G. Asp J, et al. Genes Chromosomes Cancer. 2006 Sep;45(9):820-8. doi: 10.1002/gcc.20346. Genes Chromosomes Cancer. 2006. PMID: 16736500
FISH analyses of interphase nuclei and nuclear chromatin fibers of a fourth adenoma with a normal karyotype revealed that a second fusion partner gene, TCEA1, located about 2 Mb centromeric to PLAG1, also is fused to PLAG1 as a result of a cryptic 8q rearrangement. ...
FISH analyses of interphase nuclei and nuclear chromatin fibers of a fourth adenoma with a normal karyotype revealed that a second fusion pa …
Abnormal expression of YEATS4 associates with poor prognosis and promotes cell proliferation of hepatic carcinoma cell by regulation the TCEA1/DDX3 axis.
You S, Wang F, Hu Q, Li P, Zhang C, Yu Y, Zhang Y, Li Q, Bao Q, Liu P, Li J. You S, et al. Am J Cancer Res. 2018 Oct 1;8(10):2076-2087. eCollection 2018. Am J Cancer Res. 2018. PMID: 30416857 Free PMC article.
In addition, YEATS4 promoted HCC cell proliferation and colony formation by binding to and increasing the transcriptional activity of the TCEA1 promoter. Concurrently, upregulation of TCEA1 increased the stability of the DDX3 protein, a member of the DEAD box RNA he …
In addition, YEATS4 promoted HCC cell proliferation and colony formation by binding to and increasing the transcriptional activity of the …
Quantitative proteomics of HFD-induced fatty liver uncovers novel transcription factors of lipid metabolism.
Zhi S, Congcong Z, Zhiling G, Yihan Q, Yijing X, Guanjie L, Fang W, Xuehua S, Hongjie L, Xiaoni K, Yueqiu G. Zhi S, et al. Int J Biol Sci. 2022 May 1;18(8):3298-3312. doi: 10.7150/ijbs.71431. eCollection 2022. Int J Biol Sci. 2022. PMID: 35637971 Free PMC article.
Among them, 7 TFs were selected for verification, and 3 TFs were finally validated, including Rbbp4, Tcea1, and ILF2. Downregulating each of the 3 TFs could significantly promote lipid accumulation in AML12 hepatocytes, by regulating the expression of fatty acid synthesis- …
Among them, 7 TFs were selected for verification, and 3 TFs were finally validated, including Rbbp4, Tcea1, and ILF2. Downregulating …
31 results