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Page 1
Future of Biotransformation Science in the Pharmaceutical Industry.
Kramlinger VM, Dalvie D, Heck CJS, Kalgutkar AS, O'Neill J, Su D, Teitelbaum AM, Totah RA. Kramlinger VM, et al. Among authors: teitelbaum am. Drug Metab Dispos. 2022 Mar;50(3):258-267. doi: 10.1124/dmd.121.000658. Epub 2021 Dec 17. Drug Metab Dispos. 2022. PMID: 34921097
N-Methylation of BI 187004 by Thiol S-Methyltransferase.
Maw HH, Zeng X, Campbell S, Taub ME, Teitelbaum AM. Maw HH, et al. Among authors: teitelbaum am. Drug Metab Dispos. 2018 Jun;46(6):770-778. doi: 10.1124/dmd.117.079764. Epub 2018 Mar 7. Drug Metab Dispos. 2018. PMID: 29514826
Novel advances in biotransformation and bioactivation research - 2020 year in review.
Khojasteh SC, Argikar UA, Driscoll JP, Heck CJS, King L, Jackson KD, Jian W, Kalgutkar AS, Miller GP, Kramlinger V, Rietjens IMCM, Teitelbaum AM, Wang K, Wei C. Khojasteh SC, et al. Among authors: teitelbaum am. Drug Metab Rev. 2021 Aug;53(3):384-433. doi: 10.1080/03602532.2021.1916028. Epub 2021 Jun 24. Drug Metab Rev. 2021. PMID: 33910427 Free PMC article.
Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open Science.
Thamm S, Willwacher MK, Aspnes GE, Bretschneider T, Brown NF, Buschbom-Helmke S, Fox T, Gargano EM, Grabowski D, Hoenke C, Matera D, Mueck K, Peters S, Reindl S, Riether D, Schmid M, Tautermann CS, Teitelbaum AM, Trünkle C, Veser T, Winter M, Wortmann L. Thamm S, et al. Among authors: teitelbaum am. J Med Chem. 2023 Feb 23;66(4):2832-2850. doi: 10.1021/acs.jmedchem.2c01884. Epub 2023 Feb 2. J Med Chem. 2023. PMID: 36727857 Free PMC article.
Correction to: The Absolute Bioavailability, Absorption, Distribution, Metabolism, and Excretion of BI 425809 Administered as an Oral Dose or an Oral Dose with an Intravenous Microtracer Dose of [14C]‑BI 425809 in Healthy Males.
Burkard U, Desch M, Shatillo Y, Wunderlich G, Mack SR, Schlecker C, Teitelbaum AM, Liu P, Chan TS. Burkard U, et al. Among authors: teitelbaum am. Clin Drug Investig. 2022 Apr;42(4):375. doi: 10.1007/s40261-022-01134-w. Clin Drug Investig. 2022. PMID: 35286627 Free PMC article. No abstract available.
The Absolute Bioavailability, Absorption, Distribution, Metabolism, and Excretion of BI 425809 Administered as an Oral Dose or an Oral Dose with an Intravenous Microtracer Dose of [14C]-BI 425809 in Healthy Males.
Burkard U, Desch M, Shatillo Y, Wunderlich G, Mack SR, Schlecker C, Teitelbaum AM, Liu P, Chan TS. Burkard U, et al. Among authors: teitelbaum am. Clin Drug Investig. 2022 Jan;42(1):87-99. doi: 10.1007/s40261-021-01111-9. Epub 2021 Dec 22. Clin Drug Investig. 2022. PMID: 34936055 Free PMC article. Clinical Trial.
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