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Antibody-Drug Conjugates with Pyrrole-Based KSP Inhibitors as the Payload Class.
Lerchen HG, Wittrock S, Stelte-Ludwig B, Sommer A, Berndt S, Griebenow N, Rebstock AS, Johannes S, Cancho-Grande Y, Mahlert C, Greven S, Terjung C. Lerchen HG, et al. Among authors: terjung c. Angew Chem Int Ed Engl. 2018 Nov 12;57(46):15243-15247. doi: 10.1002/anie.201807619. Epub 2018 Oct 15. Angew Chem Int Ed Engl. 2018. PMID: 30180286
Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis.
Bah GS, Schneckener S, Hahnel SR, Bayang NH, Fieseler H, Schmuck GM, Krebber R, Sarr A, Terjung C, Ngangyung HF, Ekale DD, Mfopit YM, Rufener L, Graham-Brown J, Tanya VN, Glenschek-Sieberth M, Kulke D, Makepeace BL. Bah GS, et al. Among authors: terjung c. PLoS Pathog. 2021 Jun 2;17(6):e1009601. doi: 10.1371/journal.ppat.1009601. eCollection 2021 Jun. PLoS Pathog. 2021. PMID: 34077488 Free PMC article.
Potent and Selective Human Prostaglandin F (FP) Receptor Antagonist (BAY-6672) for the Treatment of Idiopathic Pulmonary Fibrosis (IPF).
Beck H, Thaler T, Meibom D, Meininghaus M, Jörißen H, Dietz L, Terjung C, Bairlein M, von Bühler CJ, Anlauf S, Fürstner C, Stellfeld T, Schneider D, Gericke KM, Buyck T, Lovis K, Münster U, Anlahr J, Kersten E, Levilain G, Marossek V, Kast R. Beck H, et al. Among authors: terjung c. J Med Chem. 2020 Oct 22;63(20):11639-11662. doi: 10.1021/acs.jmedchem.0c00834. Epub 2020 Oct 8. J Med Chem. 2020. PMID: 32969660