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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1991 2
1993 5
1995 7
1996 3
1997 2
1998 2
1999 1
2000 1
2001 1
2002 2
2003 1
2004 1
2005 2
2006 1
2007 2
2008 1
2009 1
2024 0

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35 results

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Page 1
Dipeptides as effective prodrugs of the unnatural amino acid (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740), a selective group II metabotropic glutamate receptor agonist.
Bueno AB, Collado I, de Dios A, Domínguez C, Martín JA, Martín LM, Martínez-Grau MA, Montero C, Pedregal C, Catlow J, Coffey DS, Clay MP, Dantzig AH, Lindstrom T, Monn JA, Jiang H, Schoepp DD, Stratford RE, Tabas LB, Tizzano JP, Wright RA, Herin MF. Bueno AB, et al. Among authors: tizzano jp. J Med Chem. 2005 Aug 11;48(16):5305-20. doi: 10.1021/jm050235r. J Med Chem. 2005. PMID: 16078848
The triple uptake inhibitor (1R,5S)-(+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0] hexane hydrochloride (DOV 21947) reduces body weight and plasma triglycerides in rodent models of diet-induced obesity.
Tizzano JP, Stribling DS, Perez-Tilve D, Strack A, Frassetto A, Chen RZ, Fong TM, Shearman L, Krieter PA, Tschöp MH, Skolnick P, Basile AS. Tizzano JP, et al. J Pharmacol Exp Ther. 2008 Mar;324(3):1111-26. doi: 10.1124/jpet.107.133132. Epub 2007 Dec 18. J Pharmacol Exp Ther. 2008. PMID: 18089843
Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s).
Johnson MP, Barda D, Britton TC, Emkey R, Hornback WJ, Jagdmann GE, McKinzie DL, Nisenbaum ES, Tizzano JP, Schoepp DD. Johnson MP, et al. Among authors: tizzano jp. Psychopharmacology (Berl). 2005 Apr;179(1):271-83. doi: 10.1007/s00213-004-2099-9. Epub 2005 Feb 17. Psychopharmacology (Berl). 2005. PMID: 15717213
35 results