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Page 1
Tjap1/Pilt Is a cis-Golgi-Associated Protein Required for Golgi Integrity and Normal Drug Transporter Expression in Brain Microvascular Endothelial Cells In Vitro.
Mi J, Schoder A, Sun A, Meybohm P, Burek M. Mi J, et al. Pharmaceutics. 2026 May 28;18(6):665. doi: 10.3390/pharmaceutics18060665. Pharmaceutics. 2026. PMID: 42357281 Free PMC article.
Tjap1 knockout induced pronounced Golgi fragmentation BMECs. Importantly, Tjap1 knockout significantly downregulated mRNA-expression of Abcb1a, Abcb1b, Abcc4, Slc2a1, Slc7a1, Slc7a5 and Tfrc, while Abcg2 was upregulated. At the protein level, a decrease in the prote …
Tjap1 knockout induced pronounced Golgi fragmentation BMECs. Importantly, Tjap1 knockout significantly downregulated mRNA-expr …
HMGN3 represses transcription of epithelial regulators to promote migration of cholangiocarcinoma in a SNAI2-dependent manner.
Sorin S, Kubota S, Hamidi S, Yokomizo-Nakano T, Vaeteewoottacharn K, Wongkham S, Waraasawapati S, Pairojkul C, Bai J, Morii M, Sheng G, Sawanyawisuth K, Sashida G. Sorin S, et al. FASEB J. 2022 Jul;36(7):e22345. doi: 10.1096/fj.202200386R. FASEB J. 2022. PMID: 35635715
HMGN3 inhibited the expression of and blocked the intracellular polarities of epithelial regulator genes, such as the CDH1/E-cadherin and TJAP1 genes in CCA cells. A chromatin immunoprecipitation sequencing analysis revealed that HMGN3 required the transcription factor SNA …
HMGN3 inhibited the expression of and blocked the intracellular polarities of epithelial regulator genes, such as the CDH1/E-cadherin and …
Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2.
Weeratunga S, Gormal RS, Liu M, Eldershaw D, Livingstone EK, Malapaka A, Wallis TP, Bademosi AT, Jiang A, Healy MD, Meunier FA, Collins BM. Weeratunga S, et al. J Biol Chem. 2024 Jan;300(1):105541. doi: 10.1016/j.jbc.2023.105541. Epub 2023 Dec 9. J Biol Chem. 2024. PMID: 38072052 Free PMC article.
Validation of Mint1 interaction with a new predicted binder TJAP1 (tight junction-associated protein 1) provides experimental support that AlphaFold2 can correctly predict interactions across such large-scale datasets. ...
Validation of Mint1 interaction with a new predicted binder TJAP1 (tight junction-associated protein 1) provides experimental support …
Actions of colony-stimulating factor 3 on the maturing oocyte and developing embryo in cattle.
Jannaman EA, Xiao Y, Hansen PJ. Jannaman EA, et al. J Anim Sci. 2020 Apr 1;98(4):skaa115. doi: 10.1093/jas/skaa115. J Anim Sci. 2020. PMID: 32277240 Free PMC article.
Transcript abundance of 10 genes was increased by 100 ng/mL CSF3, including markers of epiblast (NANOG, SOX2), hypoblast (ALPL, FN1, KDM2B, and PDGFRA), epiblast and hypoblast (HNF4A) and trophectoderm (TJAP1). Results are indicative that concentrations of CSF3 higher than …
Transcript abundance of 10 genes was increased by 100 ng/mL CSF3, including markers of epiblast (NANOG, SOX2), hypoblast (ALPL, FN1, KDM2B, …
Capturing microRNA targets using an RNA-induced silencing complex (RISC)-trap approach.
Cambronne XA, Shen R, Auer PL, Goodman RH. Cambronne XA, et al. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20473-8. doi: 10.1073/pnas.1218887109. Epub 2012 Nov 26. Proc Natl Acad Sci U S A. 2012. PMID: 23184980 Free PMC article.
Two previously unknown miR-132 targets identified with RISCtrap, adaptor protein CT10 regulator of kinase 1 (CRK1) and tight junction-associated protein 1 (TJAP1), were shown to be endogenously regulated by miR-132 in adult mouse forebrain. The datasets, moreover, differed …
Two previously unknown miR-132 targets identified with RISCtrap, adaptor protein CT10 regulator of kinase 1 (CRK1) and tight junction-associ …
Hypoxia-Induced MicroRNA-212/132 Alter Blood-Brain Barrier Integrity Through Inhibition of Tight Junction-Associated Proteins in Human and Mouse Brain Microvascular Endothelial Cells.
Burek M, König A, Lang M, Fiedler J, Oerter S, Roewer N, Bohnert M, Thal SC, Blecharz-Lang KG, Woitzik J, Thum T, Förster CY. Burek M, et al. Transl Stroke Res. 2019 Dec;10(6):672-683. doi: 10.1007/s12975-018-0683-2. Epub 2019 Jan 8. Transl Stroke Res. 2019. PMID: 30617994 Free PMC article.
We identified and validated tight junction proteins claudin-1 (Cldn1), junctional adhesion molecule 3 (Jam3), and tight junction-associated protein 1 (Tjap1) as potential miR-212/132 targets. Over-expression of miRs led to a decrease in mRNA and protein expression of Cldn1 …
We identified and validated tight junction proteins claudin-1 (Cldn1), junctional adhesion molecule 3 (Jam3), and tight junction-associated …
Induction of gut leakage in young broiler chickens fed a diet with low rye inclusion.
Santos RR, Ooosterveer-van der Doelen MAM, Tersteeg-Zijderveld MHG, Molist F, Gehring R. Santos RR, et al. Heliyon. 2021 Dec 4;7(12):e08547. doi: 10.1016/j.heliyon.2021.e08547. eCollection 2021 Dec. Heliyon. 2021. PMID: 34917817 Free PMC article.
Serum levels of FITC-d, D-lactate, tight-junction-associated protein 1 (TJAP1), citrulline and ovotransferrin were determined. A significant increase in FITC-d levels was observed in the 14-day-old birds fed the non-supplemented rye diet, and no other serum markers were af …
Serum levels of FITC-d, D-lactate, tight-junction-associated protein 1 (TJAP1), citrulline and ovotransferrin were determined. A sign …
Modulation of microbial communities and mucosal gene expression in chicken intestines after galactooligosaccharides delivery In Ovo.
Slawinska A, Dunislawska A, Plowiec A, Radomska M, Lachmanska J, Siwek M, Tavaniello S, Maiorano G. Slawinska A, et al. PLoS One. 2019 Feb 27;14(2):e0212318. doi: 10.1371/journal.pone.0212318. eCollection 2019. PLoS One. 2019. PMID: 30811518 Free PMC article.
Panel (2) contained genes involved in intestinal barrier function (MUC6, CLDN1 and TJAP1) and nutrients sensing (FFAR2 and FFAR4, GLUT1, GLUT2 and GLUT5). GOS increased the relative abundance of Bifidobacterium in caecum (from 1.3% to 3.9%). ...
Panel (2) contained genes involved in intestinal barrier function (MUC6, CLDN1 and TJAP1) and nutrients sensing (FFAR2 and FFAR4, GLU …
Prenatal Exposure to Per- and Polyfluoroalkyl Substances, Umbilical Cord Blood DNA Methylation, and Cardio-Metabolic Indicators in Newborns: The Healthy Start Study.
Starling AP, Liu C, Shen G, Yang IV, Kechris K, Borengasser SJ, Boyle KE, Zhang W, Smith HA, Calafat AM, Hamman RF, Adgate JL, Dabelea D. Starling AP, et al. Environ Health Perspect. 2020 Dec;128(12):127014. doi: 10.1289/EHP6888. Epub 2020 Dec 24. Environ Health Perspect. 2020. PMID: 33356526 Free PMC article.
Methylation at one DMP (cg18587484), annotated to the gene TJAP1, was associated with perfluorooctanoate (PFOA) at FDR < 0.05. Comb-p detected between 4 and 15 DMRs for each PFAS. ...

Methylation at one DMP (cg18587484), annotated to the gene TJAP1, was associated with perfluorooctanoate (PFOA) at FDR < 0.05. Co

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14 results