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Page 1
Envelope protein ubiquitination drives entry and pathogenesis of Zika virus.
Giraldo MI, Xia H, Aguilera-Aguirre L, Hage A, van Tol S, Shan C, Xie X, Sturdevant GL, Robertson SJ, McNally KL, Meade-White K, Azar SR, Rossi SL, Maury W, Woodson M, Ramage H, Johnson JR, Krogan NJ, Morais MC, Best SM, Shi PY, Rajsbaum R. Giraldo MI, et al. Among authors: van tol s. Nature. 2020 Sep;585(7825):414-419. doi: 10.1038/s41586-020-2457-8. Epub 2020 Jul 8. Nature. 2020. PMID: 32641828 Free PMC article.
The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity.
Hage A, Bharaj P, van Tol S, Giraldo MI, Gonzalez-Orozco M, Valerdi KM, Warren AN, Aguilera-Aguirre L, Xie X, Widen SG, Moulton HM, Lee B, Johnson JR, Krogan NJ, García-Sastre A, Shi PY, Freiberg AN, Rajsbaum R. Hage A, et al. Among authors: van tol s. Cell Rep. 2022 Mar 8;38(10):110434. doi: 10.1016/j.celrep.2022.110434. Cell Rep. 2022. PMID: 35263596 Free PMC article.
Lighting the way to host-directed immunotherapeutics.
van Tol S, Hage A, Rajsbaum R. van Tol S, et al. Cell Chem Biol. 2022 Jul 21;29(7):1067-1070. doi: 10.1016/j.chembiol.2022.06.009. Cell Chem Biol. 2022. PMID: 35868235 Free PMC article.
Ebola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication.
Rodríguez-Salazar CA, van Tol S, Mailhot O, Gonzalez-Orozco M, Galdino GT, Warren AN, Teruel N, Behera P, Afreen KS, Zhang L, Juelich TL, Smith JK, Zylber MI, Freiberg AN, Najmanovich RJ, Giraldo MI, Rajsbaum R. Rodríguez-Salazar CA, et al. Among authors: van tol s. PLoS Biol. 2024 Feb 29;22(2):e3002544. doi: 10.1371/journal.pbio.3002544. eCollection 2024 Feb. PLoS Biol. 2024. PMID: 38422166 Free PMC article.
TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replication.
Gonzalez-Orozco M, Tseng HC, Hage A, Xia H, Behera P, Afreen K, Peñaflor-Tellez Y, Giraldo MI, Huante M, Puebla-Clark L, van Tol S, Odle A, Crown M, Teruel N, Shelite TR, Menachery V, Endsley M, Endsley JJ, Najmanovich RJ, Bashton M, Stephens R, Shi PY, Xie X, Freiberg AN, Rajsbaum R. Gonzalez-Orozco M, et al. Among authors: van tol s. bioRxiv [Preprint]. 2024 Jun 17:2024.06.17.599107. doi: 10.1101/2024.06.17.599107. bioRxiv. 2024. Update in: Nat Commun. 2024 Nov 30;15(1):10438. doi: 10.1038/s41467-024-54762-5 PMID: 38948778 Free PMC article. Updated. Preprint.
The TRIMendous Role of TRIMs in Virus-Host Interactions.
van Tol S, Hage A, Giraldo MI, Bharaj P, Rajsbaum R. van Tol S, et al. Vaccines (Basel). 2017 Aug 22;5(3):23. doi: 10.3390/vaccines5030023. Vaccines (Basel). 2017. PMID: 28829373 Free PMC article. Review.
TRIM Proteins in Host Defense and Viral Pathogenesis.
Giraldo MI, Hage A, van Tol S, Rajsbaum R. Giraldo MI, et al. Among authors: van tol s. Curr Clin Microbiol Rep. 2020;7(4):101-114. doi: 10.1007/s40588-020-00150-8. Epub 2020 Aug 8. Curr Clin Microbiol Rep. 2020. PMID: 32837832 Free PMC article. Review.
Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly.
van Tol S, Kalveram B, Ilinykh PA, Ronk A, Huang K, Aguilera-Aguirre L, Bharaj P, Hage A, Atkins C, Giraldo MI, Wakamiya M, Gonzalez-Orozco M, Warren AN, Bukreyev A, Freiberg AN, Rajsbaum R. van Tol S, et al. PLoS Pathog. 2022 May 9;18(5):e1010532. doi: 10.1371/journal.ppat.1010532. eCollection 2022 May. PLoS Pathog. 2022. PMID: 35533195 Free PMC article.
65 results