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2012 | 3 |
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tomas m[au]
(597 results)?
Structure-activity relationship studies of 4-benzyl-1H-pyrazol-3-yl β-d-glucopyranoside derivatives as potent and selective sodium glucose co-transporter 1 (SGLT1) inhibitors with therapeutic activity on postprandial hyperglycemia.
Bioorg Med Chem. 2012 Nov 15;20(22):6598-612. doi: 10.1016/j.bmc.2012.09.037. Epub 2012 Sep 24.
Bioorg Med Chem. 2012.
PMID: 23062824
KGA-2727, a novel selective inhibitor of a high-affinity sodium glucose cotransporter (SGLT1), exhibits antidiabetic efficacy in rodent models.
Shibazaki T, Tomae M, Ishikawa-Takemura Y, Fushimi N, Itoh F, Yamada M, Isaji M.
Shibazaki T, et al. Among authors: tomae m.
J Pharmacol Exp Ther. 2012 Aug;342(2):288-96. doi: 10.1124/jpet.112.193045. Epub 2012 Apr 26.
J Pharmacol Exp Ther. 2012.
PMID: 22537769
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Design, synthesis, and structure-activity relationships of a series of 4-benzyl-5-isopropyl-1H-pyrazol-3-yl β-D-glycopyranosides substituted with novel hydrophilic groups as highly potent inhibitors of sodium glucose co-transporter 1 (SGLT1).
Fushimi N, Teranishi H, Shimizu K, Yonekubo S, Ohno K, Miyagi T, Itoh F, Shibazaki T, Tomae M, Ishikawa-Takemura Y, Nakabayashi T, Kamada N, Yamauchi Y, Kobayashi S, Isaji M.
Fushimi N, et al. Among authors: tomae m.
Bioorg Med Chem. 2013 Feb 1;21(3):748-65. doi: 10.1016/j.bmc.2012.11.041. Epub 2012 Dec 5.
Bioorg Med Chem. 2013.
PMID: 23273606
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SLC5A9/SGLT4, a new Na+-dependent glucose transporter, is an essential transporter for mannose, 1,5-anhydro-D-glucitol, and fructose.
Tazawa S, Yamato T, Fujikura H, Hiratochi M, Itoh F, Tomae M, Takemura Y, Maruyama H, Sugiyama T, Wakamatsu A, Isogai T, Isaji M.
Tazawa S, et al. Among authors: tomae m.
Life Sci. 2005 Jan 14;76(9):1039-50. doi: 10.1016/j.lfs.2004.10.016.
Life Sci. 2005.
PMID: 15607332
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