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2020 5
2021 3
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Page 1
Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition.
Priem B, van Leent MMT, Teunissen AJP, Sofias AM, Mourits VP, Willemsen L, Klein ED, Oosterwijk RS, Meerwaldt AE, Munitz J, Prévot G, Vera Verschuur A, Nauta SA, van Leeuwen EM, Fisher EL, de Jong KAM, Zhao Y, Toner YC, Soultanidis G, Calcagno C, Bomans PHH, Friedrich H, Sommerdijk N, Reiner T, Duivenvoorden R, Zupančič E, Di Martino JS, Kluza E, Rashidian M, Ploegh HL, Dijkhuizen RM, Hak S, Pérez-Medina C, Bravo-Cordero JJ, de Winther MPJ, Joosten LAB, van Elsas A, Fayad ZA, Rialdi A, Torre D, Guccione E, Ochando J, Netea MG, Griffioen AW, Mulder WJM. Priem B, et al. Among authors: toner yc. Cell. 2020 Oct 29;183(3):786-801.e19. doi: 10.1016/j.cell.2020.09.059. Cell. 2020. PMID: 33125893
Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking.
Sofias AM, Toner YC, Meerwaldt AE, van Leent MMT, Soultanidis G, Elschot M, Gonai H, Grendstad K, Flobak Å, Neckmann U, Wolowczyk C, Fisher EL, Reiner T, Davies CL, Bjørkøy G, Teunissen AJP, Ochando J, Pérez-Medina C, Mulder WJM, Hak S. Sofias AM, et al. Among authors: toner yc. ACS Nano. 2020 Jul 28;14(7):7832-7846. doi: 10.1021/acsnano.9b08693. Epub 2020 May 20. ACS Nano. 2020. PMID: 32413260 Free PMC article.
Probing myeloid cell dynamics in ischaemic heart disease by nanotracer hot-spot imaging.
Senders ML, Meerwaldt AE, van Leent MMT, Sanchez-Gaytan BL, van de Voort JC, Toner YC, Maier A, Klein ED, Sullivan NAT, Sofias AM, Groenen H, Faries C, Oosterwijk RS, van Leeuwen EM, Fay F, Chepurko E, Reiner T, Duivenvoorden R, Zangi L, Dijkhuizen RM, Hak S, Swirski FK, Nahrendorf M, Pérez-Medina C, Teunissen AJP, Fayad ZA, Calcagno C, Strijkers GJ, Mulder WJM. Senders ML, et al. Among authors: toner yc. Nat Nanotechnol. 2020 May;15(5):398-405. doi: 10.1038/s41565-020-0642-4. Epub 2020 Apr 20. Nat Nanotechnol. 2020. PMID: 32313216 Free PMC article.
Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis.
Panizzi P, Krohn-Grimberghe M, Keliher E, Ye YX, Grune J, Frodermann V, Sun Y, Muse CG, Bushey K, Iwamoto Y, van Leent MMT, Meerwaldt A, Toner YC, Munitz J, Maier A, Soultanidis G, Calcagno C, Pérez-Medina C, Carlucci G, Riddell KP, Barney S, Horne G, Anderson B, Maddur-Appajaiah A, Verhamme IM, Bock PE, Wojtkiewicz GR, Courties G, Swirski FK, Church WR, Walz PH, Tillson DM, Mulder WJM, Nahrendorf M. Panizzi P, et al. Among authors: toner yc. Sci Transl Med. 2020 Nov 4;12(568):eaay2104. doi: 10.1126/scitranslmed.aay2104. Sci Transl Med. 2020. PMID: 33148623 Free PMC article.
Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs.
Nahrendorf M, Hoyer FF, Meerwaldt AE, van Leent MMT, Senders ML, Calcagno C, Robson PM, Soultanidis G, Pérez-Medina C, Teunissen AJP, Toner YC, Ishikawa K, Fish K, Sakurai K, van Leeuwen EM, Klein ED, Sofias AM, Reiner T, Rohde D, Aguirre AD, Wojtkiewicz G, Schmidt S, Iwamoto Y, Izquierdo-Garcia D, Caravan P, Swirski FK, Weissleder R, Mulder WJM. Nahrendorf M, et al. Among authors: toner yc. Circ Cardiovasc Imaging. 2020 Oct;13(10):e010586. doi: 10.1161/CIRCIMAGING.120.010586. Epub 2020 Oct 20. Circ Cardiovasc Imaging. 2020. PMID: 33076700
Prosaposin mediates inflammation in atherosclerosis.
van Leent MMT, Beldman TJ, Toner YC, Lameijer MA, Rother N, Bekkering S, Teunissen AJP, Zhou X, van der Meel R, Malkus J, Nauta SA, Klein ED, Fay F, Sanchez-Gaytan BL, Pérez-Medina C, Kluza E, Ye YX, Wojtkiewicz G, Fisher EA, Swirski FK, Nahrendorf M, Zhang B, Li Y, Zhang B, Joosten LAB, Pasterkamp G, Boltjes A, Fayad ZA, Lutgens E, Netea MG, Riksen NP, Mulder WJM, Duivenvoorden R. van Leent MMT, et al. Among authors: toner yc. Sci Transl Med. 2021 Mar 10;13(584):eabe1433. doi: 10.1126/scitranslmed.abe1433. Sci Transl Med. 2021. PMID: 33692130
A modular approach toward producing nanotherapeutics targeting the innate immune system.
van Leent MMT, Meerwaldt AE, Berchouchi A, Toner YC, Burnett ME, Klein ED, Verschuur AVD, Nauta SA, Munitz J, Prévot G, van Leeuwen EM, Ordikhani F, Mourits VP, Calcagno C, Robson PM, Soultanidis G, Reiner T, Joosten RRM, Friedrich H, Madsen JC, Kluza E, van der Meel R, Joosten LAB, Netea MG, Ochando J, Fayad ZA, Pérez-Medina C, Mulder WJM, Teunissen AJP. van Leent MMT, et al. Among authors: toner yc. Sci Adv. 2021 Mar 5;7(10):eabe7853. doi: 10.1126/sciadv.abe7853. Print 2021 Mar. Sci Adv. 2021. PMID: 33674313 Free PMC article.
Employing nanobodies for immune landscape profiling by PET imaging in mice.
Teunissen AJP, Abousaway OB, Munitz J, van Leent MMT, Toner YC, Priem B, Senders ML, Pérez-Medina C, Mulder WJM, Rashidian M. Teunissen AJP, et al. Among authors: toner yc. STAR Protoc. 2021 Apr 5;2(2):100434. doi: 10.1016/j.xpro.2021.100434. eCollection 2021 Jun 18. STAR Protoc. 2021. PMID: 33899016 Free PMC article.