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Plinabulin ameliorates neutropenia induced by multiple chemotherapies through a mechanism distinct from G-CSF therapies.

Tonra JR, Lloyd GK, Mohanlal R, Huang L. Tonra JR, et al. Cancer Chemother Pharmacol. 2020 Feb;85(2):461-468. doi: 10.1007/s00280-019-03998-w. Epub 2019 Dec 6. Cancer Chemother Pharmacol. 2020. PMID: 31811421 Free PMC article.

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MMP14 is a novel target of PTH signaling in osteocytes that controls resorption by regulating soluble RANKL production.

Delgado-Calle J, Hancock B, Likine EF, Sato AY, McAndrews K, Sanudo C, Bruzzaniti A, Riancho JA, Tonra JR, Bellido T. Delgado-Calle J, et al. Among authors: tonra jr. FASEB J. 2018 May;32(5):2878-2890. doi: 10.1096/fj.201700919RRR. Epub 2018 Jan 17. FASEB J. 2018. PMID: 29401593 Free PMC article.

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Structural model of a2-subunit N-terminus and its binding interface for Arf-GEF CTH2: Implication for regulation of V-ATPase, CTH2 function and rational drug design.

Marshansky V, Hosokawa H, Merkulova M, Bakulina A, Dip PV, Thaker YR, Bjargava A, Tonra JR, Ausiello DA, Grüber G. Marshansky V, et al. Among authors: tonra jr. Curr Top Membr. 2019;83:77-106. doi: 10.1016/bs.ctm.2019.01.008. Epub 2019 Mar 22. Curr Top Membr. 2019. PMID: 31196611

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IMC-A12, a human IgG1 monoclonal antibody to the insulin-like growth factor I receptor.

Rowinsky EK, Youssoufian H, Tonra JR, Solomon P, Burtrum D, Ludwig DL. Rowinsky EK, et al. Among authors: tonra jr. Clin Cancer Res. 2007 Sep 15;13(18 Pt 2):5549s-5555s. doi: 10.1158/1078-0432.CCR-07-1109. Clin Cancer Res. 2007. PMID: 17875788 Free article. Review.

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Targeting the vascular endothelial growth factor pathway in the treatment of human malignancy.

Tonra JR, Hicklin DJ. Tonra JR, et al. Immunol Invest. 2007;36(1):3-23. doi: 10.1080/08820130600991794. Immunol Invest. 2007. PMID: 17190647 Review.

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Classical and novel directions in neurotrophin transport and research: anterograde transport of brain-derived neurotrophic factor by sensory neurons.

Tonra JR. Tonra JR. Microsc Res Tech. 1999 May 15-Jun 1;45(4-5):225-32. doi: 10.1002/(SICI)1097-0029(19990515/01)45:4/5<225::AID-JEMT6>3.0.CO;2-1. Microsc Res Tech. 1999. PMID: 10383115 Review.

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Functional significance of VEGFR-2 on ovarian cancer cells.

Spannuth WA, Nick AM, Jennings NB, Armaiz-Pena GN, Mangala LS, Danes CG, Lin YG, Merritt WM, Thaker PH, Kamat AA, Han LY, Tonra JR, Coleman RL, Ellis LM, Sood AK. Spannuth WA, et al. Among authors: tonra jr. Int J Cancer. 2009 Mar 1;124(5):1045-53. doi: 10.1002/ijc.24028. Int J Cancer. 2009. PMID: 19058181 Free PMC article.

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Antitumor Activity of IMC-038525, a Novel Oral Tubulin Polymerization Inhibitor.

Tuma MC, Malikzay A, Ouyang X, Surguladze D, Fleming J, Mitelman S, Camara M, Finnerty B, Doody J, Chekler EL, Kussie P, Tonra JR. Tuma MC, et al. Among authors: tonra jr. Transl Oncol. 2010 Oct 1;3(5):318-25. doi: 10.1593/tlo.10160. Transl Oncol. 2010. PMID: 20885894 Free PMC article.

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Preclinical rationale for combining an EGFR antibody with cisplatin/gemcitabine for the treatment of NSCLC.

Samakoglu S, Deevi DS, Li H, Wang S, Murphy M, Bao C, Bassi R, Prewett M, Tonra JR. Samakoglu S, et al. Among authors: tonra jr. Cancer Genomics Proteomics. 2012 Mar-Apr;9(2):77-92. Cancer Genomics Proteomics. 2012. PMID: 22399498

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Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2.

Duncton MA, Piatnitski Chekler EL, Katoch-Rouse R, Sherman D, Wong WC, Smith LM 2nd, Kawakami JK, Kiselyov AS, Milligan DL, Balagtas C, Hadari YR, Wang Y, Patel SN, Rolster RL, Tonra JR, Surguladze D, Mitelman S, Kussie P, Bohlen P, Doody JF. Duncton MA, et al. Among authors: tonra jr. Bioorg Med Chem. 2009 Jan 15;17(2):731-40. doi: 10.1016/j.bmc.2008.11.049. Epub 2008 Nov 24. Bioorg Med Chem. 2009. PMID: 19101155

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