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Year Number of Results
2014 1
2015 5
2016 1
2017 1
2020 2
2021 3
2022 0
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12 results
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Page 1
Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
Kleinstiver BP, Prew MS, Tsai SQ, Topkar VV, Nguyen NT, Zheng Z, Gonzales AP, Li Z, Peterson RT, Yeh JR, Aryee MJ, Joung JK. Kleinstiver BP, et al. Among authors: topkar vv. Nature. 2015 Jul 23;523(7561):481-5. doi: 10.1038/nature14592. Epub 2015 Jun 22. Nature. 2015. PMID: 26098369 Free PMC article.
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Leppek K, Byeon GW, Kladwang W, Wayment-Steele HK, Kerr CH, Xu AF, Kim DS, Topkar VV, Choe C, Rothschild D, Tiu GC, Wellington-Oguri R, Fujii K, Sharma E, Watkins AM, Nicol JJ, Romano J, Tunguz B, Participants E, Barna M, Das R. Leppek K, et al. Among authors: topkar vv. bioRxiv. 2021 Mar 30:2021.03.29.437587. doi: 10.1101/2021.03.29.437587. Preprint. bioRxiv. 2021. PMID: 33821271 Free PMC article.
Defining genome-wide CRISPR-Cas genome-editing nuclease activity with GUIDE-seq.
Malinin NL, Lee G, Lazzarotto CR, Li Y, Zheng Z, Nguyen NT, Liebers M, Topkar VV, Iafrate AJ, Le LP, Aryee MJ, Joung JK, Tsai SQ. Malinin NL, et al. Among authors: topkar vv. Nat Protoc. 2021 Dec;16(12):5592-5615. doi: 10.1038/s41596-021-00626-x. Epub 2021 Nov 12. Nat Protoc. 2021. PMID: 34773119 Review.
mRNA Transport and Local Translation in Glia.
Meservey LM, Topkar VV, Fu MM. Meservey LM, et al. Among authors: topkar vv. Trends Cell Biol. 2021 Jun;31(6):419-423. doi: 10.1016/j.tcb.2021.03.006. Epub 2021 Apr 8. Trends Cell Biol. 2021. PMID: 33840591
Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Kappel K, Zhang K, Su Z, Watkins AM, Kladwang W, Li S, Pintilie G, Topkar VV, Rangan R, Zheludev IN, Yesselman JD, Chiu W, Das R. Kappel K, et al. Among authors: topkar vv. Nat Methods. 2020 Jul;17(7):699-707. doi: 10.1038/s41592-020-0878-9. Epub 2020 Jul 2. Nat Methods. 2020. PMID: 32616928 Free PMC article.
12 results