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Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter.
Hiraizumi M, Akashi T, Murasaki K, Kishida H, Kumanomidou T, Torimoto N, Nureki O, Miyaguchi I. Hiraizumi M, et al. Among authors: torimoto n. Nat Struct Mol Biol. 2024 Jan;31(1):159-169. doi: 10.1038/s41594-023-01134-0. Epub 2023 Dec 6. Nat Struct Mol Biol. 2024. PMID: 38057552 Free PMC article.
Helices F-G are important for the substrate specificities of CYP3A7.
Torimoto N, Ishii I, Toyama K, Hata M, Tanaka K, Shimomura H, Nakamura H, Ariyoshi N, Ohmori S, Kitada M. Torimoto N, et al. Drug Metab Dispos. 2007 Mar;35(3):484-92. doi: 10.1124/dmd.106.011304. Epub 2006 Dec 18. Drug Metab Dispos. 2007. PMID: 17178770