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Cytochrome P450 in Pharmacogenetics: An Update.

Tornio A, Backman JT. Tornio A, et al. Adv Pharmacol. 2018;83:3-32. doi: 10.1016/bs.apha.2018.04.007. Adv Pharmacol. 2018. PMID: 29801580 Review.

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Enantiospecific Pharmacogenomics of Fluvastatin.

Hirvensalo P, Tornio A, Neuvonen M, Kiander W, Kidron H, Paile-Hyvärinen M, Tapaninen T, Backman JT, Niemi M. Hirvensalo P, et al. Among authors: tornio a. Clin Pharmacol Ther. 2019 Sep;106(3):668-680. doi: 10.1002/cpt.1463. Epub 2019 May 14. Clin Pharmacol Ther. 2019. PMID: 30989645 Free PMC article.

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Role of gemfibrozil as an inhibitor of CYP2C8 and membrane transporters.

Tornio A, Neuvonen PJ, Niemi M, Backman JT. Tornio A, et al. Expert Opin Drug Metab Toxicol. 2017 Jan;13(1):83-95. doi: 10.1080/17425255.2016.1227791. Epub 2016 Aug 31. Expert Opin Drug Metab Toxicol. 2017. PMID: 27548563 Review.

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Sex-Based Outcomes After Coronary Artery Bypass Grafting.

Kytö V, Sipilä J, Tornio A, Rautava P, Gunn J. Kytö V, et al. Among authors: tornio a. Ann Thorac Surg. 2021 Dec;112(6):1974-1981. doi: 10.1016/j.athoracsur.2021.01.014. Epub 2021 Jan 20. Ann Thorac Surg. 2021. PMID: 33484674

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Performance of Plasma Coproporphyrin I and III as OATP1B1 Biomarkers in Humans.

Neuvonen M, Tornio A, Hirvensalo P, Backman JT, Niemi M. Neuvonen M, et al. Among authors: tornio a. Clin Pharmacol Ther. 2021 Dec;110(6):1622-1632. doi: 10.1002/cpt.2429. Epub 2021 Oct 15. Clin Pharmacol Ther. 2021. PMID: 34580865 Clinical Trial.

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A common missense variant of LILRB5 is associated with statin intolerance and myalgia.

K Siddiqui M, Maroteau C, Veluchamy A, Tornio A, Tavendale R, Carr F, Abelega NU, Carr D, Bloch K, Hallberg P, Yue QY, Pearson ER, Colhoun HM, Morris AD, Dow E, George J, Pirmohamed M, Ridker PM, Doney ASF, Alfirevic A, Wadelius M, Maitland-van der Zee AH, Chasman DI, Palmer CNA; PREDICTION-ADR Consortium. K Siddiqui M, et al. Among authors: tornio a. Eur Heart J. 2017 Dec 21;38(48):3569-3575. doi: 10.1093/eurheartj/ehx467. Eur Heart J. 2017. PMID: 29020356 Free PMC article. Clinical Trial.

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Placental transporter-mediated drug interactions and offspring congenital anomalies.

Ellfolk M, Tornio A, Niemi M, Leinonen MK, Lahesmaa-Korpinen AM, Malm H. Ellfolk M, et al. Among authors: tornio a. Br J Clin Pharmacol. 2020 May;86(5):868-879. doi: 10.1111/bcp.14191. Epub 2020 Jan 20. Br J Clin Pharmacol. 2020. PMID: 31823387 Free PMC article.

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Clinical Studies on Drug-Drug Interactions Involving Metabolism and Transport: Methodology, Pitfalls, and Interpretation.

Tornio A, Filppula AM, Niemi M, Backman JT. Tornio A, et al. Clin Pharmacol Ther. 2019 Jun;105(6):1345-1361. doi: 10.1002/cpt.1435. Epub 2019 Apr 20. Clin Pharmacol Ther. 2019. PMID: 30916389 Free PMC article. Review.

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UGT1A3 and Sex Are Major Determinants of Telmisartan Pharmacokinetics-A Comprehensive Pharmacogenomic Study.

Hirvensalo P, Tornio A, Launiainen T, Paile-Hyvärinen M, Tapaninen T, Neuvonen M, Backman JT, Niemi M. Hirvensalo P, et al. Among authors: tornio a. Clin Pharmacol Ther. 2020 Oct;108(4):885-895. doi: 10.1002/cpt.1928. Epub 2020 Jul 10. Clin Pharmacol Ther. 2020. PMID: 32498119

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Drug interactions with oral antidiabetic agents: pharmacokinetic mechanisms and clinical implications.

Tornio A, Niemi M, Neuvonen PJ, Backman JT. Tornio A, et al. Trends Pharmacol Sci. 2012 Jun;33(6):312-22. doi: 10.1016/j.tips.2012.03.001. Epub 2012 Apr 2. Trends Pharmacol Sci. 2012. PMID: 22475684 Review.

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