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Inhibition of the Alanine-Serine-Cysteine-1 Transporter by BMS-466442.
Torrecillas IR, Conde-Ceide S, de Lucas AI, Garcı A Molina A, Trabanco AA, Lavreysen H, Pardo L, Tresadern G. Torrecillas IR, et al. ACS Chem Neurosci. 2019 May 15;10(5):2510-2517. doi: 10.1021/acschemneuro.9b00019. Epub 2019 Mar 14. ACS Chem Neurosci. 2019. PMID: 30821959
A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia.
Marín-Ramos NI, Balabasquer M, Ortega-Nogales FJ, Torrecillas IR, Gil-Ordóñez A, Marcos-Ramiro B, Aguilar-Garrido P, Cushman I, Romero A, Medrano FJ, Gajate C, Mollinedo F, Philips MR, Campillo M, Gallardo M, Martín-Fontecha M, López-Rodríguez ML, Ortega-Gutiérrez S. Marín-Ramos NI, et al. Among authors: torrecillas ir. J Med Chem. 2019 Jul 11;62(13):6035-6046. doi: 10.1021/acs.jmedchem.9b00145. Epub 2019 Jun 19. J Med Chem. 2019. PMID: 31181882
Sitamaquine overcomes ABC-mediated resistance to miltefosine and antimony in Leishmania.
Pérez-Victoria JM, Bavchvarov BI, Torrecillas IR, Martínez-García M, López-Martín C, Campillo M, Castanys S, Gamarro F. Pérez-Victoria JM, et al. Among authors: torrecillas ir. Antimicrob Agents Chemother. 2011 Aug;55(8):3838-44. doi: 10.1128/AAC.00065-11. Epub 2011 Jun 6. Antimicrob Agents Chemother. 2011. PMID: 21646479 Free PMC article.
Development of non-peptide ligands of growth factor receptor-bound protein 2-SRC homology 2 domain using molecular modeling and NMR spectroscopy.
Orcajo-Rincón ÁL, Ortega-Gutiérrez S, Serrano P, Torrecillas IR, Wüthrich K, Campillo M, Pardo L, Viso A, Benhamú B, López-Rodríguez ML. Orcajo-Rincón ÁL, et al. Among authors: torrecillas ir. J Med Chem. 2011 Feb 24;54(4):1096-100. doi: 10.1021/jm101478n. Epub 2011 Jan 27. J Med Chem. 2011. PMID: 21271718
Biological evaluation, structure-activity relationships, and three-dimensional quantitative structure-activity relationship studies of dihydro-beta-agarofuran sesquiterpenes as modulators of P-glycoprotein-dependent multidrug resistance.
Reyes CP, Muñoz-Martínez F, Torrecillas IR, Mendoza CR, Gamarro F, Bazzocchi IL, Núñez MJ, Pardo L, Castanys S, Campillo M, Jiménez IA. Reyes CP, et al. Among authors: torrecillas ir. J Med Chem. 2007 Oct 4;50(20):4808-17. doi: 10.1021/jm070290v. Epub 2007 Sep 12. J Med Chem. 2007. PMID: 17850057