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A Cocktail Interaction Study Evaluating the Drug-Drug Interaction Potential of the Perpetrator Drug ASP8477 at Multiple Ascending Dose Levels.

Treijtel N, Collins C, van Bruijnsvoort M, Fuhr R, Ernault E, Gangaram-Panday S, Passier P. Treijtel N, et al. Clin Pharmacol Drug Dev. 2019 May;8(4):529-540. doi: 10.1002/cpdd.660. Epub 2019 Feb 7. Clin Pharmacol Drug Dev. 2019. PMID: 30730615 Free PMC article. Clinical Trial.

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Pilocarpine-Induced Effects on Salivary Secretion as a Pharmacological Biomarker for Cholinergic Parasympathetic Activation.

Treijtel N, Groenendaal-van de Meent D, Michon I, Korstanje C, Meijer J, Francke K, Grossmann M, de Vries M. Treijtel N, et al. Clin Pharmacol Drug Dev. 2022 Jan;11(1):25-33. doi: 10.1002/cpdd.1048. Epub 2021 Nov 26. Clin Pharmacol Drug Dev. 2022. PMID: 34826362

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A systematic review on disease-drug-drug interactions with immunomodulating drugs: A critical appraisal of risk assessment and drug labelling.

de Jong LM, Klomp SD, Treijtel N, Rissmann R, Swen JJ, Manson ML. de Jong LM, et al. Among authors: treijtel n. Br J Clin Pharmacol. 2022 Apr 28. doi: 10.1111/bcp.15372. Online ahead of print. Br J Clin Pharmacol. 2022. PMID: 35484780 Review.

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Clearance and clearance inhibition of the HIV-1 protease inhibitors ritonavir and saquinavir in sandwich-cultured rat hepatocytes and rat microsomes.

Treijtel N, van Eijkeren JC, Nijmeijer S, de Greef-van der Sandt IC, Freidig AP. Treijtel N, et al. Toxicol In Vitro. 2009 Feb;23(1):185-93. doi: 10.1016/j.tiv.2008.11.001. Epub 2008 Nov 13. Toxicol In Vitro. 2009. PMID: 19038324

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The use of sandwich-cultured rat hepatocytes to determine the intrinsic clearance of compounds with different extraction ratios: 7-ethoxycoumarin and warfarin.

Treijtel N, van Helvoort H, Barendregt A, Blaauboer BJ, van Eijkeren JC. Treijtel N, et al. Drug Metab Dispos. 2005 Sep;33(9):1325-32. doi: 10.1124/dmd.105.004390. Epub 2005 Jun 10. Drug Metab Dispos. 2005. PMID: 15951450

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A set-point model with oscillatory behavior predicts the time course of 8-OH-DPAT-induced hypothermia.

Zuideveld KP, Maas HJ, Treijtel N, Hulshof J, van der Graaf PH, Peletier LA, Danhof M. Zuideveld KP, et al. Among authors: treijtel n. Am J Physiol Regul Integr Comp Physiol. 2001 Dec;281(6):R2059-71. doi: 10.1152/ajpregu.2001.281.6.R2059. Am J Physiol Regul Integr Comp Physiol. 2001. PMID: 11705793 Free article.

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A competitive interaction model predicts the effect of WAY-100,635 on the time course of R-(+)-8-hydroxy-2-(di-n-propylamino)tetralin-induced hypothermia.

Zuideveld KP, Treijtel N, Maas HJ, Gubbens-Stibbe JM, Peletier LA, van Der Graaf PH, Danhof M. Zuideveld KP, et al. Among authors: treijtel n. J Pharmacol Exp Ther. 2002 Jan;300(1):330-8. doi: 10.1124/jpet.300.1.330. J Pharmacol Exp Ther. 2002. PMID: 11752133

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Modeling the in vitro intrinsic clearance of the slowly metabolized compound tolbutamide determined in sandwich-cultured rat hepatocytes.

Treijtel N, Barendregt A, Freidig AP, Blaauboer BJ, van Eijkeren JC. Treijtel N, et al. Drug Metab Dispos. 2004 Aug;32(8):884-91. doi: 10.1124/dmd.32.8.884. Drug Metab Dispos. 2004. PMID: 15258115

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Enantioselective high-performance liquid chromatographic analysis of the 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin. Application to a pharmacokinetic-pharmacodynamic study in rats.

Zuideveld KP, Treijtel N, Van der Graaf PH, Danhof M. Zuideveld KP, et al. Among authors: treijtel n. J Chromatogr B Biomed Sci Appl. 2000 Jan 28;738(1):67-73. doi: 10.1016/s0378-4347(99)00493-4. J Chromatogr B Biomed Sci Appl. 2000. PMID: 10778927

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