Tremaine LM[au] - Search Results

Year	Number of Results
1973	1
1978	1
1979	1
1980	1
1982	1
1984	1
1985	3
1989	3
1992	1
1997	3
2004	1
2005	3
2006	1
2007	1
2008	1
2010	1
2011	2
2012	2
2016	2
2017	6
2018	6
2019	1
2023	0

1

Assessment of drug metabolism enzyme and transporter pharmacogenetics in drug discovery and early development: perspectives of the I-PWG.

Brian W, Tremaine LM, Arefayene M, de Kanter R, Evers R, Guo Y, Kalabus J, Lin W, Loi CM, Xiao G. Brian W, et al. Among authors: tremaine lm. Pharmacogenomics. 2016 Apr;17(6):615-31. doi: 10.2217/pgs.16.9. Epub 2016 Apr 5. Pharmacogenomics. 2016. PMID: 27045656 Review.

2

In vitro cytochrome P450 inhibition data and the prediction of drug-drug interactions: qualitative relationships, quantitative predictions, and the rank-order approach.

Obach RS, Walsky RL, Venkatakrishnan K, Houston JB, Tremaine LM. Obach RS, et al. Among authors: tremaine lm. Clin Pharmacol Ther. 2005 Dec;78(6):582-92. doi: 10.1016/j.clpt.2005.09.004. Clin Pharmacol Ther. 2005. PMID: 16338274 Review. No abstract available.

3

In Vitro-In Vivo Extrapolation of OATP1B-Mediated Drug-Drug Interactions in Cynomolgus Monkey.

Ufuk A, Kosa RE, Gao H, Bi YA, Modi S, Gates D, Rodrigues AD, Tremaine LM, Varma MVS, Houston JB, Galetin A. Ufuk A, et al. Among authors: tremaine lm. J Pharmacol Exp Ther. 2018 Jun;365(3):688-699. doi: 10.1124/jpet.118.247767. Epub 2018 Apr 11. J Pharmacol Exp Ther. 2018. PMID: 29643253

4

Erratum to: Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes.

Bi YA, Scialis RJ, Lazzaro S, Mathialagan S, Kimoto E, Keefer J, Zhang H, Vildhede AM, Costales C, Rodrigues AD, Tremaine LM, Varma MVS. Bi YA, et al. Among authors: tremaine lm. AAPS J. 2017 May;19(3):882. doi: 10.1208/s12248-017-0061-0. AAPS J. 2017. PMID: 28233243 No abstract available.

5

A novel relay method for determining low-clearance values.

Di L, Trapa P, Obach RS, Atkinson K, Bi YA, Wolford AC, Tan B, McDonald TS, Lai Y, Tremaine LM. Di L, et al. Among authors: tremaine lm. Drug Metab Dispos. 2012 Sep;40(9):1860-5. doi: 10.1124/dmd.112.046425. Epub 2012 May 29. Drug Metab Dispos. 2012. PMID: 22645091

6

Transporter-Mediated Hepatic Uptake Plays an Important Role in the Pharmacokinetics and Drug-Drug Interactions of Montelukast.

Varma MV, Kimoto E, Scialis R, Bi Y, Lin J, Eng H, Kalgutkar AS, El-Kattan AF, Rodrigues AD, Tremaine LM. Varma MV, et al. Among authors: tremaine lm. Clin Pharmacol Ther. 2017 Mar;101(3):406-415. doi: 10.1002/cpt.520. Epub 2016 Nov 18. Clin Pharmacol Ther. 2017. PMID: 27648490

7

Tissue distribution and elimination of [14C]apixaban in rats.

Wang L, He K, Maxwell B, Grossman SJ, Tremaine LM, Humphreys WG, Zhang D. Wang L, et al. Among authors: tremaine lm. Drug Metab Dispos. 2011 Feb;39(2):256-64. doi: 10.1124/dmd.110.036442. Epub 2010 Nov 11. Drug Metab Dispos. 2011. PMID: 21071521

8

Extended Clearance Classification System (ECCS) informed approach for evaluating investigational drugs as substrates of drug transporters.

Varma MV, El-Kattan AF, Feng B, Steyn SJ, Maurer TS, Scott DO, Rodrigues AD, Tremaine LM. Varma MV, et al. Among authors: tremaine lm. Clin Pharmacol Ther. 2017 Jul;102(1):33-36. doi: 10.1002/cpt.595. Epub 2017 Feb 3. Clin Pharmacol Ther. 2017. PMID: 27984654 No abstract available.

9

Simultaneous Assessment of Transporter-Mediated Drug-Drug Interactions Using a Probe Drug Cocktail in Cynomolgus Monkey.

Kosa RE, Lazzaro S, Bi YA, Tierney B, Gates D, Modi S, Costales C, Rodrigues AD, Tremaine LM, Varma MV. Kosa RE, et al. Among authors: tremaine lm. Drug Metab Dispos. 2018 Aug;46(8):1179-1189. doi: 10.1124/dmd.118.081794. Epub 2018 Jun 7. Drug Metab Dispos. 2018. PMID: 29880631

10

Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes.

Bi YA, Scialis RJ, Lazzaro S, Mathialagan S, Kimoto E, Keefer J, Zhang H, Vildhede AM, Costales C, Rodrigues AD, Tremaine LM, Varma MVS. Bi YA, et al. Among authors: tremaine lm. AAPS J. 2017 May;19(3):787-796. doi: 10.1208/s12248-017-0051-2. Epub 2017 Feb 10. AAPS J. 2017. PMID: 28188574

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