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Page 1
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
Trepte P, Secker C, Kostova S, Maseko SB, Choi SG, Blavier J, Minia I, Ramos ES, Cassonnet P, Golusik S, Zenkner M, Beetz S, Liebich MJ, Scharek N, Schütz A, Sperling M, Lisurek M, Wang Y, Spirohn K, Hao T, Calderwood MA, Hill DE, Landthaler M, Olivet J, Twizere JC, Vidal M, Wanker EE. Trepte P, et al. bioRxiv [Preprint]. 2023 Jun 14:2023.06.14.544560. doi: 10.1101/2023.06.14.544560. bioRxiv. 2023. Update in: Mol Syst Biol. 2024 Apr;20(4):428-457. doi: 10.1038/s44320-024-00019-8. PMID: 37398436 Free PMC article. Updated. Preprint.
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
Trepte P, Secker C, Olivet J, Blavier J, Kostova S, Maseko SB, Minia I, Silva Ramos E, Cassonnet P, Golusik S, Zenkner M, Beetz S, Liebich MJ, Scharek N, Schütz A, Sperling M, Lisurek M, Wang Y, Spirohn K, Hao T, Calderwood MA, Hill DE, Landthaler M, Choi SG, Twizere JC, Vidal M, Wanker EE. Trepte P, et al. Mol Syst Biol. 2024 Apr;20(4):428-457. doi: 10.1038/s44320-024-00019-8. Epub 2024 Mar 11. Mol Syst Biol. 2024. PMID: 38467836 Free PMC article.
Maximizing binary interactome mapping with a minimal number of assays.
Choi SG, Olivet J, Cassonnet P, Vidalain PO, Luck K, Lambourne L, Spirohn K, Lemmens I, Dos Santos M, Demeret C, Jones L, Rangarajan S, Bian W, Coutant EP, Janin YL, van der Werf S, Trepte P, Wanker EE, De Las Rivas J, Tavernier J, Twizere JC, Hao T, Hill DE, Vidal M, Calderwood MA, Jacob Y. Choi SG, et al. Among authors: trepte p. Nat Commun. 2019 Aug 29;10(1):3907. doi: 10.1038/s41467-019-11809-2. Nat Commun. 2019. PMID: 31467278 Free PMC article.
Current Approaches Toward Quantitative Mapping of the Interactome.
Buntru A, Trepte P, Klockmeier K, Schnoegl S, Wanker EE. Buntru A, et al. Among authors: trepte p. Front Genet. 2016 May 4;7:74. doi: 10.3389/fgene.2016.00074. eCollection 2016. Front Genet. 2016. PMID: 27200083 Free PMC article.
Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.
Fossati G, Morini R, Corradini I, Antonucci F, Trepte P, Edry E, Sharma V, Papale A, Pozzi D, Defilippi P, Meier JC, Brambilla R, Turco E, Rosenblum K, Wanker EE, Ziv NE, Menna E, Matteoli M. Fossati G, et al. Among authors: trepte p. Cell Death Differ. 2015 Sep;22(9):1425-36. doi: 10.1038/cdd.2014.227. Epub 2015 Feb 13. Cell Death Differ. 2015. PMID: 25678324 Free PMC article.
14 results