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A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells.

Chen Y, Tristan CA, Chen L, Jovanovic VM, Malley C, Chu PH, Ryu S, Deng T, Ormanoglu P, Tao D, Fang Y, Slamecka J, Hong H, LeClair CA, Michael S, Austin CP, Simeonov A, Singeç I. Chen Y, et al. Among authors: tristan ca. Nat Methods. 2021 May;18(5):528-541. doi: 10.1038/s41592-021-01126-2. Epub 2021 May 3. Nat Methods. 2021. PMID: 33941937 Free PMC article.

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Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells.

Tristan CA, Ormanoglu P, Slamecka J, Malley C, Chu PH, Jovanovic VM, Gedik Y, Jethmalani Y, Bonney C, Barnaeva E, Braisted J, Mallanna SK, Dorjsuren D, Iannotti MJ, Voss TC, Michael S, Simeonov A, Singeç I. Tristan CA, et al. Stem Cell Reports. 2021 Dec 14;16(12):3076-3092. doi: 10.1016/j.stemcr.2021.11.004. Epub 2021 Dec 2. Stem Cell Reports. 2021. PMID: 34861164 Free PMC article.

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Chemically Defined Neural Conversion of Human Pluripotent Stem Cells.

Chen Y, Tristan CA, Mallanna SK, Ormanoglu P, Titus S, Simeonov A, Singeç I. Chen Y, et al. Among authors: tristan ca. Methods Mol Biol. 2019;1919:59-72. doi: 10.1007/978-1-4939-9007-8_5. Methods Mol Biol. 2019. PMID: 30656621 Free PMC article.

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Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells.

Tristan CA, Ormanoglu P, Slamecka J, Malley C, Chu PH, Jovanovic VM, Gedik Y, Bonney C, Barnaeva E, Braisted J, Mallanna SK, Dorjsuren D, Iannotti MJ, Voss TC, Michael S, Simeonov A, Singeç I. Tristan CA, et al. bioRxiv. 2020 Aug 3:2020.08.03.235242. doi: 10.1101/2020.08.03.235242. Preprint. bioRxiv. 2020. PMID: 32793899 Free PMC article.

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Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma.

Kambach DM, Halim AS, Cauer AG, Sun Q, Tristan CA, Celiku O, Kesarwala AH, Shankavaram U, Batchelor E, Stommel JM. Kambach DM, et al. Among authors: tristan ca. Oncotarget. 2017 Feb 28;8(9):14860-14875. doi: 10.18632/oncotarget.14740. Oncotarget. 2017. PMID: 28118603 Free PMC article.

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Human Pluripotent Stem Cells for High-Throughput Drug Screening and Characterization of Small Molecules.

Ryu S, Chu PH, Malley C, Braisted J, Ormanoglu P, Huang R, Itkin M, Itkin Z, Shinn P, Klumpp-Thomas C, Michael S, Tristan CA, Simeonov A, Singeç I. Ryu S, et al. Among authors: tristan ca. Methods Mol Biol. 2022;2454:811-827. doi: 10.1007/7651_2021_394. Methods Mol Biol. 2022. PMID: 34128205

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Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade.

Tristan CA, Ramos A, Shahani N, Emiliani FE, Nakajima H, Noeh CC, Kato Y, Takeuchi T, Noguchi T, Kadowaki H, Sedlak TW, Ishizuka K, Ichijo H, Sawa A. Tristan CA, et al. J Biol Chem. 2015 Jan 2;290(1):56-64. doi: 10.1074/jbc.M114.596205. Epub 2014 Nov 12. J Biol Chem. 2015. PMID: 25391652 Free PMC article.

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Correction to: Human Pluripotent Stem Cells for High-Throughput Drug Screening and Characterization of Small Molecules.

Ryu S, Chu PH, Malley C, Braisted J, Ormanoglu P, Huang R, Itkin M, Itkin Z, Shinn P, Klumpp-Thomas C, Michael S, Tristan CA, Simeonov A, Singeç I. Ryu S, et al. Among authors: tristan ca. Methods Mol Biol. 2022;2454:829. doi: 10.1007/7651_2021_458. Methods Mol Biol. 2022. PMID: 35141848

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Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody.

Shanker A, Brooks AD, Tristan CA, Wine JW, Elliott PJ, Yagita H, Takeda K, Smyth MJ, Murphy WJ, Sayers TJ. Shanker A, et al. Among authors: tristan ca. J Natl Cancer Inst. 2008 May 7;100(9):649-62. doi: 10.1093/jnci/djn113. Epub 2008 Apr 29. J Natl Cancer Inst. 2008. PMID: 18445820 Free PMC article.

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