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Year Number of Results
2013 1
2016 2
2017 2
2018 2
2019 3
2020 1
2021 1
2022 0
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12 results
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Page 1
High-Throughput Discovery and Characterization of Human Transcriptional Effectors.
Tycko J, DelRosso N, Hess GT, Aradhana, Banerjee A, Mukund A, Van MV, Ego BK, Yao D, Spees K, Suzuki P, Marinov GK, Kundaje A, Bassik MC, Bintu L. Tycko J, et al. Cell. 2020 Dec 23;183(7):2020-2035.e16. doi: 10.1016/j.cell.2020.11.024. Epub 2020 Dec 15. Cell. 2020. PMID: 33326746 Free PMC article.
Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.
Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, Simeonov DR, Suliman N, Li R, Xu J, Flynn RA, Kundaje A, Khavari PA, Marson A, Corn JE, Quertermous T, Greenleaf WJ, Chang HY. Mumbach MR, et al. Among authors: tycko j. Nat Genet. 2017 Nov;49(11):1602-1612. doi: 10.1038/ng.3963. Epub 2017 Sep 25. Nat Genet. 2017. PMID: 28945252 Free PMC article.
Gene drives for schistosomiasis transmission control.
Maier T, Wheeler NJ, Namigai EKO, Tycko J, Grewelle RE, Woldeamanuel Y, Klohe K, Perez-Saez J, Sokolow SH, De Leo GA, Yoshino TP, Zamanian M, Reinhard-Rupp J. Maier T, et al. Among authors: tycko j. PLoS Negl Trop Dis. 2019 Dec 19;13(12):e0007833. doi: 10.1371/journal.pntd.0007833. eCollection 2019 Dec. PLoS Negl Trop Dis. 2019. PMID: 31856157 Free PMC article. Review.
Lessons learned from the clinical development and market authorization of Glybera.
Bryant LM, Christopher DM, Giles AR, Hinderer C, Rodriguez JL, Smith JB, Traxler EA, Tycko J, Wojno AP, Wilson JM. Bryant LM, et al. Among authors: tycko j. Hum Gene Ther Clin Dev. 2013 Jun;24(2):55-64. doi: 10.1089/humc.2013.087. Epub 2013 Jun 29. Hum Gene Ther Clin Dev. 2013. PMID: 23808604 Free PMC article. Review.
Identification of Guide-Intrinsic Determinants of Cas9 Specificity.
Huston NC, Tycko J, Tillotson EL, Wilson CJ, Myer VE, Jayaram H, Steinberg BE. Huston NC, et al. Among authors: tycko j. CRISPR J. 2019 Jun;2(3):172-185. doi: 10.1089/crispr.2019.0009. CRISPR J. 2019. PMID: 31225747 Free PMC article.
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements.
Tycko J, Wainberg M, Marinov GK, Ursu O, Hess GT, Ego BK, Aradhana, Li A, Truong A, Trevino AE, Spees K, Yao D, Kaplow IM, Greenside PG, Morgens DW, Phanstiel DH, Snyder MP, Bintu L, Greenleaf WJ, Kundaje A, Bassik MC. Tycko J, et al. Nat Commun. 2019 Sep 6;10(1):4063. doi: 10.1038/s41467-019-11955-7. Nat Commun. 2019. PMID: 31492858 Free PMC article.
12 results