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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1995 1
1997 2
1998 1
1999 1
2000 2
2001 3
2002 4
2004 4
2005 3
2006 1
2007 3
2008 2
2009 3
2010 3
2011 2
2013 3
2014 1
2016 2
2017 3
2018 1
2019 1
2020 2
2021 4
2022 2
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51 results
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Page 1
Development of IL-5 receptor antagonists.
Uings I, McKinnon M. Uings I, et al. Curr Pharm Des. 2002;8(20):1837-44. doi: 10.2174/1381612023393800. Curr Pharm Des. 2002. PMID: 12171535 Review.
Designing corticosteroid drugs for pulmonary selectivity.
Biggadike K, Uings I, Farrow SN. Biggadike K, et al. Among authors: uings i. Proc Am Thorac Soc. 2004;1(4):352-5. doi: 10.1513/pats.200409-048TA. Proc Am Thorac Soc. 2004. PMID: 16113457 Review.
Cell receptors and cell signalling.
Uings IJ, Farrow SN. Uings IJ, et al. Mol Pathol. 2000 Dec;53(6):295-9. doi: 10.1136/mp.53.6.295. Mol Pathol. 2000. PMID: 11193047 Free PMC article. Review.
The development of highly potent and selective small molecule correctors of Z α1-antitrypsin misfolding.
Liddle J, Pearce AC, Arico-Muendel C, Belyanskaya S, Brewster A, Brown M, Chung CW, Denis A, Dodic N, Dossang A, Eddershaw P, Klimaszewska D, Haq I, Holmes DS, Jagger A, Jakhria T, Jigorel E, Lind K, Messer J, Neu M, Olszewski A, Ronzoni R, Rowedder J, Rüdiger M, Skinner S, Smith KJ, Trottet L, Uings I, Zhu Z, Irving JA, Lomas DA. Liddle J, et al. Among authors: uings i. Bioorg Med Chem Lett. 2021 Jun 1;41:127973. doi: 10.1016/j.bmcl.2021.127973. Epub 2021 Mar 19. Bioorg Med Chem Lett. 2021. PMID: 33753261
Development of a small molecule that corrects misfolding and increases secretion of Z α1 -antitrypsin.
Lomas DA, Irving JA, Arico-Muendel C, Belyanskaya S, Brewster A, Brown M, Chung CW, Dave H, Denis A, Dodic N, Dossang A, Eddershaw P, Klimaszewska D, Haq I, Holmes DS, Hutchinson JP, Jagger AM, Jakhria T, Jigorel E, Liddle J, Lind K, Marciniak SJ, Messer J, Neu M, Olszewski A, Ordonez A, Ronzoni R, Rowedder J, Rüdiger M, Skinner S, Smith KJ, Terry R, Trottet L, Uings I, Wilson S, Zhu Z, Pearce AC. Lomas DA, et al. Among authors: uings i. EMBO Mol Med. 2021 Mar 5;13(3):e13167. doi: 10.15252/emmm.202013167. Epub 2021 Jan 29. EMBO Mol Med. 2021. PMID: 33512066 Free PMC article.
CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model.
Ketley A, Wojciechowska M, Ghidelli-Disse S, Bamborough P, Ghosh TK, Morato ML, Sedehizadeh S, Malik NA, Tang Z, Powalowska P, Tanner M, Billeter-Clark R, Trueman RC, Geiszler PC, Agostini A, Othman O, Bösche M, Bantscheff M, Rüdiger M, Mossakowska DE, Drewry DH, Zuercher WJ, Thornton CA, Drewes G, Uings I, Hayes CJ, Brook JD. Ketley A, et al. Among authors: uings i. Sci Transl Med. 2020 Apr 29;12(541):eaaz2415. doi: 10.1126/scitranslmed.aaz2415. Sci Transl Med. 2020. PMID: 32350131
The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis.
Liddle J, Beaufils B, Binnie M, Bouillot A, Denis AA, Hann MM, Haslam CP, Holmes DS, Hutchinson JP, Kranz M, McBride A, Mirguet O, Mole DJ, Mowat CG, Pal S, Rowland P, Trottet L, Uings IJ, Walker AL, Webster SP. Liddle J, et al. Among authors: uings ij. Bioorg Med Chem Lett. 2017 May 1;27(9):2023-2028. doi: 10.1016/j.bmcl.2017.02.078. Epub 2017 Mar 9. Bioorg Med Chem Lett. 2017. PMID: 28336141 Free article.
51 results