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Recognition of psychostimulants, antidepressants, and other inhibitors of synaptic neurotransmitter uptake by the plasma membrane monoamine transporters.

Surratt CK, Ukairo OT, Ramanujapuram S. Surratt CK, et al. Among authors: ukairo ot. AAPS J. 2005 Oct 27;7(3):E739-51. doi: 10.1208/aapsj070374. AAPS J. 2005. PMID: 16353950 Free PMC article. Review.

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Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans.

Atienzar FA, Blomme EA, Chen M, Hewitt P, Kenna JG, Labbe G, Moulin F, Pognan F, Roth AB, Suter-Dick L, Ukairo O, Weaver RJ, Will Y, Dambach DM. Atienzar FA, et al. Among authors: ukairo o. Biomed Res Int. 2016;2016:9737920. doi: 10.1155/2016/9737920. Epub 2016 Sep 5. Biomed Res Int. 2016. PMID: 27689095 Free PMC article. Review.

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Long-term stability of primary rat hepatocytes in micropatterned cocultures.

Ukairo O, Kanchagar C, Moore A, Shi J, Gaffney J, Aoyama S, Rose K, Krzyzewski S, McGeehan J, Andersen ME, Khetani SR, Lecluyse EL. Ukairo O, et al. J Biochem Mol Toxicol. 2013 Mar;27(3):204-12. doi: 10.1002/jbt.21469. Epub 2013 Jan 11. J Biochem Mol Toxicol. 2013. PMID: 23315828

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Bioactivation and toxicity of acetaminophen in a rat hepatocyte micropatterned coculture system.

Ukairo O, McVay M, Krzyzewski S, Aoyama S, Rose K, Andersen ME, Khetani SR, Lecluyse EL. Ukairo O, et al. J Biochem Mol Toxicol. 2013 Oct;27(10):471-8. doi: 10.1002/jbt.21512. Epub 2013 Aug 5. J Biochem Mol Toxicol. 2013. PMID: 23918466

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Liver safety evaluation of endothelin receptor antagonists using HepatoPac^® : A single model impact assessment on hepatocellular health, function and bile acid disposition.

Aleo MD, Ukairo O, Moore A, Irrechukwu O, Potter DM, Schneider RP. Aleo MD, et al. Among authors: ukairo o. J Appl Toxicol. 2019 Aug;39(8):1192-1207. doi: 10.1002/jat.3805. Epub 2019 May 27. J Appl Toxicol. 2019. PMID: 31134659

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Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism.

Ballard TE, Wang S, Cox LM, Moen MA, Krzyzewski S, Ukairo O, Obach RS. Ballard TE, et al. Among authors: ukairo o. Drug Metab Dispos. 2016 Feb;44(2):172-9. doi: 10.1124/dmd.115.066688. Epub 2015 Nov 25. Drug Metab Dispos. 2016. PMID: 26608083

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Use of micropatterned cocultures to detect compounds that cause drug-induced liver injury in humans.

Khetani SR, Kanchagar C, Ukairo O, Krzyzewski S, Moore A, Shi J, Aoyama S, Aleo M, Will Y. Khetani SR, et al. Among authors: ukairo o. Toxicol Sci. 2013 Mar;132(1):107-17. doi: 10.1093/toxsci/kfs326. Epub 2012 Nov 14. Toxicol Sci. 2013. PMID: 23152190

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Establishment of a hepatocyte-kupffer cell coculture model for assessment of proinflammatory cytokine effects on metabolizing enzymes and drug transporters.

Nguyen TV, Ukairo O, Khetani SR, McVay M, Kanchagar C, Seghezzi W, Ayanoglu G, Irrechukwu O, Evers R. Nguyen TV, et al. Among authors: ukairo o. Drug Metab Dispos. 2015 May;43(5):774-85. doi: 10.1124/dmd.114.061317. Epub 2015 Mar 4. Drug Metab Dispos. 2015. PMID: 25739975

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Critical role for apoptosis signal-regulating kinase 1 in the development of inflammatory K/BxN serum-induced arthritis.

Mnich SJ, Blanner PM, Hu LG, Shaffer AF, Happa FA, O'Neil S, Ukairo O, Weiss D, Welsh E, Storer C, Mbalaviele G, Ichijo H, Monahan JB, Hardy MM, Eda H. Mnich SJ, et al. Among authors: ukairo o. Int Immunopharmacol. 2010 Oct;10(10):1170-6. doi: 10.1016/j.intimp.2010.06.023. Epub 2010 Jul 6. Int Immunopharmacol. 2010. PMID: 20609399

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Fluctuation of the dopamine uptake inhibition potency of cocaine, but not amphetamine, at mammalian cells expressing the dopamine transporter.

Ukairo OT, Ramanujapuram S, Surratt CK. Ukairo OT, et al. Brain Res. 2007 Feb 2;1131(1):68-76. doi: 10.1016/j.brainres.2006.11.018. Epub 2006 Dec 13. Brain Res. 2007. PMID: 17169338 Free PMC article.

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