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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1998 2
2002 2
2003 2
2004 1
2007 1
2010 1
2011 2
2012 3
2013 1
2014 2
2018 1
2024 0

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Page 1
An iminium ion metabolite hampers the production of the pharmacologically active metabolite of a multikinase inhibitor KW-2449 in primates: irreversible inhibition of aldehyde oxidase and covalent binding with endogenous proteins.
Hosogi J, Ohashi R, Maeda H, Fujita K, Ushiki J, Kuwabara T, Yamamoto Y, Imamura T. Hosogi J, et al. Among authors: ushiki j. Biopharm Drug Dispos. 2018 Mar;39(3):164-174. doi: 10.1002/bdd.2123. Biopharm Drug Dispos. 2018. PMID: 29451686
Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate.
Kodaira H, Kusuhara H, Fujita T, Ushiki J, Fuse E, Sugiyama Y. Kodaira H, et al. Among authors: ushiki j. J Pharmacol Exp Ther. 2011 Dec;339(3):935-44. doi: 10.1124/jpet.111.180398. Epub 2011 Sep 20. J Pharmacol Exp Ther. 2011. PMID: 21934030
Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. 1. Synthesis, structure-activity relationship, and biological effects of a new class of quinazoline derivatives.
Matsuno K, Ichimura M, Nakajima T, Tahara K, Fujiwara S, Kase H, Ushiki J, Giese NA, Pandey A, Scarborough RM, Lokker NA, Yu JC, Irie J, Tsukuda E, Ide S, Oda S, Nomoto Y. Matsuno K, et al. Among authors: ushiki j. J Med Chem. 2002 Jul 4;45(14):3057-66. doi: 10.1021/jm010428o. J Med Chem. 2002. PMID: 12086491
Novel LC-MS/MS method for simultaneous quantification of KW-7158, a new drug candidate for urinary incontinence and bladder hyperactivity, and its metabolites in rat plasma: a pharmacokinetic study in male and female rats.
Maeda H, Fujita K, Kobayashi H, Ushiki J, Nakanishi T, Tamai I. Maeda H, et al. Among authors: ushiki j. Arzneimittelforschung. 2012 May;62(5):213-21. doi: 10.1055/s-0032-1301883. Epub 2012 Feb 16. Arzneimittelforschung. 2012. PMID: 22344572
18 results