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The contribution of neutrophils to bacteriophage clearance and pharmacokinetics in vivo.
Echterhof A, Dharmaraj T, Khosravi A, McBride R, Miesel L, Chia JH, Blankenberg PM, Lin KY, Shen CC, Lee YL, Yeh YC, Liao WT, Blankenberg FG, Dąbrowska K, Amanatullah DF, Frymoyer AR, Bollyky PL. Echterhof A, et al. JCI Insight. 2024 Oct 22;9(20):e181309. doi: 10.1172/jci.insight.181309. JCI Insight. 2024. PMID: 39435664 Free PMC article.
Here, we have examined the contribution of neutrophils, the most abundant phagocytes in the body, to the pharmacokinetics of i.v. administered bacteriophage in uninfected mice. A single dose of LPS-5, a bacteriophage recently used in human clinical trials to treat drug-res …
Here, we have examined the contribution of neutrophils, the most abundant phagocytes in the body, to the pharmacokinetics of i.v. adm …
83 results