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FinnGen provides genetic insights from a well-phenotyped isolated population.
Kurki MI, Karjalainen J, Palta P, Sipilä TP, Kristiansson K, Donner KM, Reeve MP, Laivuori H, Aavikko M, Kaunisto MA, Loukola A, Lahtela E, Mattsson H, Laiho P, Della Briotta Parolo P, Lehisto AA, Kanai M, Mars N, Rämö J, Kiiskinen T, Heyne HO, Veerapen K, Rüeger S, Lemmelä S, Zhou W, Ruotsalainen S, Pärn K, Hiekkalinna T, Koskelainen S, Paajanen T, Llorens V, Gracia-Tabuenca J, Siirtola H, Reis K, Elnahas AG, Sun B, Foley CN, Aalto-Setälä K, Alasoo K, Arvas M, Auro K, Biswas S, Bizaki-Vallaskangas A, Carpen O, Chen CY, Dada OA, Ding Z, Ehm MG, Eklund K, Färkkilä M, Finucane H, Ganna A, Ghazal A, Graham RR, Green EM, Hakanen A, Hautalahti M, Hedman ÅK, Hiltunen M, Hinttala R, Hovatta I, Hu X, Huertas-Vazquez A, Huilaja L, Hunkapiller J, Jacob H, Jensen JN, Joensuu H, John S, Julkunen V, Jung M, Junttila J, Kaarniranta K, Kähönen M, Kajanne R, Kallio L, Kälviäinen R, Kaprio J; FinnGen; Kerimov N, Kettunen J, Kilpeläinen E, Kilpi T, Klinger K, Kosma VM, Kuopio T, Kurra V, Laisk T, Laukkanen J, Lawless N, Liu A, Longerich S, Mägi R, Mäkelä J, Mäkitie A, Malarstig A, Mannermaa A, Maranville J, Matakidou A, Meretoja T, Mozaffari SV, Niemi MEK, Niemi M, Niiranen T, O Donnell CJ, Obeidat… See abstract for full author list ➔ Kurki MI, et al. Nature. 2023 Jan;613(7944):508-518. doi: 10.1038/s41586-022-05473-8. Epub 2023 Jan 18. Nature. 2023. PMID: 36653562 Free PMC article.
The Global, Regional, and National Burden of Adult Lip, Oral, and Pharyngeal Cancer in 204 Countries and Territories: A Systematic Analysis for the Global Burden of Disease Study 2019.
GBD 2019 Lip, Oral, and Pharyngeal Cancer Collaborators; Cunha ARD, Compton K, Xu R, Mishra R, Drangsholt MT, Antunes JLF, Kerr AR, Acheson AR, Lu D, Wallace LE, Kocarnik JM, Fu W, Dean FE, Pennini A, Henrikson HJ, Alam T, Ababneh E, Abd-Elsalam S, Abdoun M, Abidi H, Abubaker Ali H, Abu-Gharbieh E, Adane TD, Addo IY, Ahmad A, Ahmad S, Ahmed Rashid T, Akonde M, Al Hamad H, Alahdab F, Alimohamadi Y, Alipour V, Al-Maweri SA, Alsharif U, Ansari-Moghaddam A, Anwar SL, Anyasodor AE, Arabloo J, Aravkin AY, Aruleba RT, Asaad M, Ashraf T, Athari SS, Attia S, Azadnajafabad S, Azangou-Khyavy M, Badar M, Baghcheghi N, Banach M, Bardhan M, Barqawi HJ, Bashir NZ, Bashiri A, Benzian H, Bernabe E, Bhagat DS, Bhojaraja VS, Bjørge T, Bouaoud S, Braithwaite D, Briko NI, Calina D, Carreras G, Chakraborty PA, Chattu VK, Chaurasia A, Chen MX, Cho WCS, Chu DT, Chukwu IS, Chung E, Cruz-Martins N, Dadras O, Dai X, Dandona L, Dandona R, Daneshpajouhnejad P, Darvishi Cheshmeh Soltani R, Darwesh AM, Debela SA, Derbew Molla M, Dessalegn FN, Dianati-Nasab M, Digesa LE, Dixit SG, Dixit A, Djalalinia S, El Sayed I, El Tantawi M, Enyew DB, Erku DA, Ezzeddini R, Fagbamigbe AF, Falzone L, Fetensa G, Fukumoto T, Gae… See abstract for full author list ➔ GBD 2019 Lip, Oral, and Pharyngeal Cancer Collaborators, et al. JAMA Oncol. 2023 Oct 1;9(10):1401-1416. doi: 10.1001/jamaoncol.2023.2960. JAMA Oncol. 2023. PMID: 37676656 Free PMC article.
Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia.
Watterberg KL, Walsh MC, Li L, Chawla S, D'Angio CT, Goldberg RN, Hintz SR, Laughon MM, Yoder BA, Kennedy KA, McDavid GE, Backstrom-Lacy C, Das A, Crawford MM, Keszler M, Sokol GM, Poindexter BB, Ambalavanan N, Hibbs AM, Truog WE, Schmidt B, Wyckoff MH, Khan AM, Garg M, Chess PR, Reynolds AM, Moallem M, Bell EF, Meyer LR, Patel RM, Van Meurs KP, Cotten CM, McGowan EC, Hines AC, Merhar S, Peralta-Carcelen M, Wilson-Costello DE, Kilbride HW, DeMauro SB, Heyne RJ, Mosquera RA, Natarajan G, Purdy IB, Lowe JR, Maitre NL, Harmon HM, Hogden LA, Adams-Chapman I, Winter S, Malcolm WF, Higgins RD; Eunice Kennedy Shriver NICHD Neonatal Research Network. Watterberg KL, et al. N Engl J Med. 2022 Mar 24;386(12):1121-1131. doi: 10.1056/NEJMoa2114897. N Engl J Med. 2022. PMID: 35320643 Free PMC article. Clinical Trial.
Genetic Inhibition of APOL1 Pore-Forming Function Prevents APOL1-Mediated Kidney Disease.
Hung AM, Assimon VA, Chen HC, Yu Z, Vlasschaert C, Triozzi JL, Chan H, Wheless L, Wilson O, Shah SC, Mack T, Thompson T, Matheny ME, Chandrasekar S, Mozaffari SV, Chung CP, Tsao P, Susztak K, Siew ED, Estrada K, Gaziano JM, Graham RR, Tao R, Hoek M, Robinson-Cohen C, Green EM, Bick AG; Million Veteran Program. Hung AM, et al. J Am Soc Nephrol. 2023 Nov 1;34(11):1889-1899. doi: 10.1681/ASN.0000000000000219. Epub 2023 Oct 6. J Am Soc Nephrol. 2023. PMID: 37798822 Free PMC article.
Why study inner ear hair cell mitochondria?
Lesus J, Arias K, Kulaga J, Sobkiv S, Patel A, Babu V, Kambalyal A, Patel M, Padron F, Mozaffari P, Jayakumar A, Ghatalah L, Laban N, Bahari R, Perkins G, Lysakowski A. Lesus J, et al. HNO. 2019 Jun;67(6):429-433. doi: 10.1007/s00106-019-0662-2. HNO. 2019. PMID: 30969353 Free PMC article. Review.
Structural bioinformatics for rational drug design.
Mozaffari S, Moen A, Ng CY, Nicolaes GAF, Wichapong K. Mozaffari S, et al. Res Pract Thromb Haemost. 2025 Jan 23;9(1):102691. doi: 10.1016/j.rpth.2025.102691. eCollection 2025 Jan. Res Pract Thromb Haemost. 2025. PMID: 40027444 Free PMC article.
The repetitive structure of DNA clamps: An overlooked protein tandem repeat.
Arrías PN, Monzon AM, Clementel D, Mozaffari S, Piovesan D, Kajava AV, Tosatto SCE. Arrías PN, et al. J Struct Biol. 2023 Sep;215(3):108001. doi: 10.1016/j.jsb.2023.108001. Epub 2023 Jul 17. J Struct Biol. 2023. PMID: 37467824 Free article.
Each Box repeat is a betabetabetabeta module of about 60 residues, which forms a class V "beads-on-a-string" type STRP. The number of repeats present in processivity factors is organism dependent. ...
Each Box repeat is a betabetabetabeta module of about 60 residues, which forms a class V "beads-on-a-string" type STRP. The number of …
A flexible capacity-metric creatinine sensor based on polygon-shape polyvinylpyrrolidone/CuO and Fe(2)O(3) NRDs electrodeposited on three-dimensional TiO(2)-V(2)O(5)-Polypyrrole nanocomposite.
Dehghan-Manshadi H, Mazloum-Ardakani M, Mozaffari SA. Dehghan-Manshadi H, et al. Biosens Bioelectron. 2024 Feb 15;246:115881. doi: 10.1016/j.bios.2023.115881. Epub 2023 Nov 27. Biosens Bioelectron. 2024. PMID: 38042049
The innovations of the present work include these items; (i) Design and preparation of three-dimensional flexible conductive polymeric nanocomposites (3D-FCPNCs) containing polypyrrole (PPy), V(2)O(5) and TiO(2) and modification of their surface with polygon-shape polyviny …
The innovations of the present work include these items; (i) Design and preparation of three-dimensional flexible conductive polymeric nanoc …
Clinical outcomes by supplemental oxygen use in remdesivir-treated, hospitalised adults with COVID-19.
Arber N, Shah PL, Assoumou L, Rokx C, De Castro N, Bakhai A, Soriano Viladomiu A, Mateu L, Lumbreras C, Estrada V, Curran A, Sellier PO, Duffy A, Fletcher C, Mozaffari E, Haubrich R, Hodgkins P, Pozniak A, Raffi F. Arber N, et al. Infect Dis Now. 2023 Oct;53(7):104760. doi: 10.1016/j.idnow.2023.104760. Epub 2023 Jul 14. Infect Dis Now. 2023. PMID: 37454762
Microleakage in Class V Composite Restorations after Desensitizing Surface Treatment with Er:YAG and CO(2) Lasers.
Mozaffari HR, Ehteshami A, Zallaghi F, Chiniforush N, Moradi Z. Mozaffari HR, et al. Laser Ther. 2016 Dec 30;25(4):259-266. doi: 10.5978/islsm.16-OR-20. Laser Ther. 2016. PMID: 28765670 Free PMC article.
Materials and methods: This experimental study was conducted on 60 extracted sound human teeth. Class V cavities were prepared measuring 33 mm using a diamond bur. Specimens were randomly divided into 4 groups of 15. ...
Materials and methods: This experimental study was conducted on 60 extracted sound human teeth. Class V cavities were prepared measur …
32 results