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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2008 2
2009 5
2010 3
2011 5
2012 7
2013 5
2014 3
2015 3
2016 1
2017 1
2018 8
2019 5
2020 3
2021 2
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47 results
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Page 1
Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Kruse AC, Ring AM, Manglik A, Hu J, Hu K, Eitel K, Hübner H, Pardon E, Valant C, Sexton PM, Christopoulos A, Felder CC, Gmeiner P, Steyaert J, Weis WI, Garcia KC, Wess J, Kobilka BK. Kruse AC, et al. Among authors: valant c. Nature. 2013 Dec 5;504(7478):101-6. doi: 10.1038/nature12735. Epub 2013 Nov 20. Nature. 2013. PMID: 24256733 Free PMC article.
Crystal structure of the M5 muscarinic acetylcholine receptor.
Vuckovic Z, Gentry PR, Berizzi AE, Hirata K, Varghese S, Thompson G, van der Westhuizen ET, Burger WAC, Rahmani R, Valant C, Langmead CJ, Lindsley CW, Baell JB, Tobin AB, Sexton PM, Christopoulos A, Thal DM. Vuckovic Z, et al. Among authors: valant c. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):26001-26007. doi: 10.1073/pnas.1914446116. Epub 2019 Nov 26. Proc Natl Acad Sci U S A. 2019. PMID: 31772027 Free PMC article.
Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs.
Hollingsworth SA, Kelly B, Valant C, Michaelis JA, Mastromihalis O, Thompson G, Venkatakrishnan AJ, Hertig S, Scammells PJ, Sexton PM, Felder CC, Christopoulos A, Dror RO. Hollingsworth SA, et al. Among authors: valant c. Nat Commun. 2019 Jul 23;10(1):3289. doi: 10.1038/s41467-019-11062-7. Nat Commun. 2019. PMID: 31337749 Free PMC article.
Endogenous allosteric modulators of G protein-coupled receptors.
van der Westhuizen ET, Valant C, Sexton PM, Christopoulos A. van der Westhuizen ET, et al. Among authors: valant c. J Pharmacol Exp Ther. 2015 May;353(2):246-60. doi: 10.1124/jpet.114.221606. Epub 2015 Feb 3. J Pharmacol Exp Ther. 2015. PMID: 25650376 Review.
Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse Colon.
DiCello JJ, Carbone SE, Saito A, Rajasekhar P, Ceredig RA, Pham V, Valant C, Christopoulos A, Veldhuis NA, Canals M, Massotte D, Poole DP. DiCello JJ, et al. Among authors: valant c. Cell Mol Gastroenterol Hepatol. 2020;9(3):465-483. doi: 10.1016/j.jcmgh.2019.11.006. Epub 2019 Nov 20. Cell Mol Gastroenterol Hepatol. 2020. PMID: 31759144 Free PMC article.
Structure-Based Design and Discovery of New M2 Receptor Agonists.
Fish I, Stößel A, Eitel K, Valant C, Albold S, Huebner H, Möller D, Clark MJ, Sunahara RK, Christopoulos A, Shoichet BK, Gmeiner P. Fish I, et al. Among authors: valant c. J Med Chem. 2017 Nov 22;60(22):9239-9250. doi: 10.1021/acs.jmedchem.7b01113. Epub 2017 Nov 13. J Med Chem. 2017. PMID: 29094937 Free PMC article.
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