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Page 1
Genetic engineering of T cells for adoptive immunotherapy.
Varela-Rohena A, Carpenito C, Perez EE, Richardson M, Parry RV, Milone M, Scholler J, Hao X, Mexas A, Carroll RG, June CH, Riley JL. Varela-Rohena A, et al. Immunol Res. 2008;42(1-3):166-81. doi: 10.1007/s12026-008-8057-6. Immunol Res. 2008. PMID: 18841331 Free PMC article. Review.
Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells.
Cameron BJ, Gerry AB, Dukes J, Harper JV, Kannan V, Bianchi FC, Grand F, Brewer JE, Gupta M, Plesa G, Bossi G, Vuidepot A, Powlesland AS, Legg A, Adams KJ, Bennett AD, Pumphrey NJ, Williams DD, Binder-Scholl G, Kulikovskaya I, Levine BL, Riley JL, Varela-Rohena A, Stadtmauer EA, Rapoport AP, Linette GP, June CH, Hassan NJ, Kalos M, Jakobsen BK. Cameron BJ, et al. Among authors: varela rohena a. Sci Transl Med. 2013 Aug 7;5(197):197ra103. doi: 10.1126/scitranslmed.3006034. Sci Transl Med. 2013. PMID: 23926201 Free PMC article.
Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor.
Varela-Rohena A, Molloy PE, Dunn SM, Li Y, Suhoski MM, Carroll RG, Milicic A, Mahon T, Sutton DH, Laugel B, Moysey R, Cameron BJ, Vuidepot A, Purbhoo MA, Cole DK, Phillips RE, June CH, Jakobsen BK, Sewell AK, Riley JL. Varela-Rohena A, et al. Nat Med. 2008 Dec;14(12):1390-5. doi: 10.1038/nm.1779. Epub 2008 Nov 9. Nat Med. 2008. PMID: 18997777 Free PMC article.
Improved Expansion and In Vivo Function of Patient T Cells by a Serum-free Medium.
Medvec AR, Ecker C, Kong H, Winters EA, Glover J, Varela-Rohena A, Riley JL. Medvec AR, et al. Among authors: varela rohena a. Mol Ther Methods Clin Dev. 2017 Nov 7;8:65-74. doi: 10.1016/j.omtm.2017.11.001. eCollection 2018 Mar 16. Mol Ther Methods Clin Dev. 2017. PMID: 29687031 Free PMC article.
Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.
Carpenito C, Milone MC, Hassan R, Simonet JC, Lakhal M, Suhoski MM, Varela-Rohena A, Haines KM, Heitjan DF, Albelda SM, Carroll RG, Riley JL, Pastan I, June CH. Carpenito C, et al. Among authors: varela rohena a. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3360-5. doi: 10.1073/pnas.0813101106. Epub 2009 Feb 11. Proc Natl Acad Sci U S A. 2009. PMID: 19211796 Free PMC article.
Differential Reliance on Lipid Metabolism as a Salvage Pathway Underlies Functional Differences of T Cell Subsets in Poor Nutrient Environments.
Ecker C, Guo L, Voicu S, Gil-de-Gómez L, Medvec A, Cortina L, Pajda J, Andolina M, Torres-Castillo M, Donato JL, Mansour S, Zynda ER, Lin PY, Varela-Rohena A, Blair IA, Riley JL. Ecker C, et al. Among authors: varela rohena a. Cell Rep. 2018 Apr 17;23(3):741-755. doi: 10.1016/j.celrep.2018.03.084. Cell Rep. 2018. PMID: 29669281 Free PMC article.