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Engineered deletions of HIV replicate conditionally to reduce disease in nonhuman primates.
Pitchai FNN, Tanner EJ, Khetan N, Vasen G, Levrel C, Kumar AJ, Pandey S, Ordonez T, Barnette P, Spencer D, Jung SY, Glazier J, Thompson C, Harvey-Vera A, Son HI, Son HI, Strathdee SA, Holguin L, Urak R, Burnett J, Burgess W, Busman-Sahay K, Estes JD, Hessell A, Fennessey CM, Keele BF, Haigwood NL, Weinberger LS. Pitchai FNN, et al. Among authors: vasen g. Science. 2024 Aug 9;385(6709):eadn5866. doi: 10.1126/science.adn5866. Epub 2024 Aug 9. Science. 2024. PMID: 39116226
A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters.
Chaturvedi S, Beutler N, Pablo M, Vasen G, Chen X, Calia G, Buie L, Rodick R, Smith D, Rogers T, Weinberger LS. Chaturvedi S, et al. Among authors: vasen g. bioRxiv [Preprint]. 2022 Aug 11:2022.08.10.503534. doi: 10.1101/2022.08.10.503534. bioRxiv. 2022. Update in: Proc Natl Acad Sci U S A. 2022 Sep 27;119(39):e2204624119. doi: 10.1073/pnas.2204624119. PMID: 35982679 Free PMC article. Updated. Preprint.
Identification of a therapeutic interfering particle-A single-dose SARS-CoV-2 antiviral intervention with a high barrier to resistance.
Chaturvedi S, Vasen G, Pablo M, Chen X, Beutler N, Kumar A, Tanner E, Illouz S, Rahgoshay D, Burnett J, Holguin L, Chen PY, Ndjamen B, Ott M, Rodick R, Rogers T, Smith DM, Weinberger LS. Chaturvedi S, et al. Among authors: vasen g. Cell. 2021 Dec 9;184(25):6022-6036.e18. doi: 10.1016/j.cell.2021.11.004. Epub 2021 Nov 10. Cell. 2021. PMID: 34838159 Free PMC article.
15 results