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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1958 3
1959 1
1960 1
1962 1
1963 1
1964 3
1965 1
1991 1
1992 4
1993 6
1994 4
1995 21
1996 27
1997 30
1998 52
1999 85
2000 116
2001 148
2002 185
2003 204
2004 296
2005 395
2006 666
2007 769
2008 841
2009 952
2010 1144
2011 1427
2012 1575
2013 1711
2014 1834
2015 1950
2016 1691
2017 1433
2018 1483
2019 1585
2020 1723
2021 1553
2022 1345
2023 1300
2024 1379
2025 16

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24,428 results

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Page 1
VEGFA and tumour angiogenesis.
Claesson-Welsh L, Welsh M. Claesson-Welsh L, et al. J Intern Med. 2013 Feb;273(2):114-27. doi: 10.1111/joim.12019. J Intern Med. 2013. PMID: 23216836 Free article. Review.
In this review we summarize the current understanding of signal transduction downstream of vascular endothelial growth factor A (VEGFA) and its receptor VEGFR2, and the relationship between these signal transduction pathways and the hallmark responses of VEGFA, angi …
In this review we summarize the current understanding of signal transduction downstream of vascular endothelial growth factor A (VEGFA …
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Zou G, Zhang X, Wang L, Li X, Xie T, Zhao J, Yan J, Wang L, Ye H, Jiao S, Xiang R, Shi Y. Zou G, et al. Theranostics. 2020 May 22;10(15):6839-6853. doi: 10.7150/thno.43622. eCollection 2020. Theranostics. 2020. PMID: 32550907 Free PMC article.
However, the current methods using anti-vascular endothelial growth factor A (VEGFA) antibodies or inhibitors targeting VEGFA receptors are not as efficient as expected partly due to their low efficiencies in blocking VEGFA signaling in vivo. Until now, there …
However, the current methods using anti-vascular endothelial growth factor A (VEGFA) antibodies or inhibitors targeting VEGFA …
VEGFA Isoforms as Pro-Angiogenic Therapeutics for Cerebrovascular Diseases.
White AL, Bix GJ. White AL, et al. Biomolecules. 2023 Apr 20;13(4):702. doi: 10.3390/biom13040702. Biomolecules. 2023. PMID: 37189449 Free PMC article. Review.
The lack of beneficial effects in humans and the difficulty in medicinal translation may be due in part to administration methods and VEGFA's ability to increase vascular permeability. One solution to mitigate the side effects of VEGFA may be found in the VEGFA …
The lack of beneficial effects in humans and the difficulty in medicinal translation may be due in part to administration methods and VEG …
Astrocytic VEGFA: An essential mediator in blood-brain-barrier disruption in Parkinson's disease.
Lan G, Wang P, Chan RB, Liu Z, Yu Z, Liu X, Yang Y, Zhang J. Lan G, et al. Glia. 2022 Feb;70(2):337-353. doi: 10.1002/glia.24109. Epub 2021 Oct 29. Glia. 2022. PMID: 34713920
This process involved the expression and release of vascular endothelial growth factor A (VEGFA) and nitric oxide (NO) from oligomeric alpha-syn treated astrocytes. Increased levels of VEGFA and iNOS were also observed in the brain of PD patients. ...Finally, the pr …
This process involved the expression and release of vascular endothelial growth factor A (VEGFA) and nitric oxide (NO) from oligomeri …
Cardamonin attenuates cerebral ischemia/reperfusion injury by activating the HIF-1alpha/VEGFA pathway.
Ni H, Li J, Zheng J, Zhou B. Ni H, et al. Phytother Res. 2022 Apr;36(4):1736-1747. doi: 10.1002/ptr.7409. Epub 2022 Feb 10. Phytother Res. 2022. PMID: 35142404
Cardamonin increased OGD/R-induced activation of the HIF-1alpha/VEGFA pathway. Inhibition of the HIF-1alpha/VEGFA signaling using inhibitor relieved the effect of cardamonin on cell viability, permeability and apoptosis in HBMECs under OGD/R. Cardamonin mitigated br …
Cardamonin increased OGD/R-induced activation of the HIF-1alpha/VEGFA pathway. Inhibition of the HIF-1alpha/VEGFA signaling us …
Modulation of VEGFA Signaling During Heart Regeneration in Zebrafish.
Chowdhury K, Lai SL, Marín-Juez R. Chowdhury K, et al. Methods Mol Biol. 2022;2475:297-312. doi: 10.1007/978-1-0716-2217-9_22. Methods Mol Biol. 2022. PMID: 35451767 Review.
Here, we summarize the main findings on VEGFA's role during cardiac repair and regeneration, with a particular focus on zebrafish as a regenerative model. Moreover, we provide a comprehensive overview of available tools to modulate Vegfa expression and action in zeb …
Here, we summarize the main findings on VEGFA's role during cardiac repair and regeneration, with a particular focus on zebrafish as …
CircRNA-miRNA-VEGFA: an important pathway to regulate cancer pathogenesis.
Zhang L, Zhang Y, Li X, Gao H, Chen X, Li P. Zhang L, et al. Front Pharmacol. 2023 May 10;14:1049742. doi: 10.3389/fphar.2023.1049742. eCollection 2023. Front Pharmacol. 2023. PMID: 37234708 Free PMC article. Review.
Many factors are associated with cancer pathogenesis, including vascular endothelial growth factor-A (VEGFA) and circular RNAs (circRNA). VEGFA is a pivotal regulator of vascular development such as angiogenesis, which is an important process in cancer development. …
Many factors are associated with cancer pathogenesis, including vascular endothelial growth factor-A (VEGFA) and circular RNAs (circR …
VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk.
Wang L, Zhang L, Zhao L, Shao S, Ning Q, Jing X, Zhang Y, Zhao F, Liu X, Gu S, Zhao X, Luo M. Wang L, et al. Int J Biol Sci. 2024 Jan 1;20(2):446-463. doi: 10.7150/ijbs.86085. eCollection 2024. Int J Biol Sci. 2024. PMID: 38169627 Free PMC article.
Our study underscores the crosstalk between TNBC cells and TAMs mediated by VEGFA and further clarifies the role and underlying mechanisms of the VEGFA/NRP-1/GAPVD1 axis in regulating cancer stemness. We also document an immunosuppressive function of VEGFA in …
Our study underscores the crosstalk between TNBC cells and TAMs mediated by VEGFA and further clarifies the role and underlying mecha …
Association of VEGFA polymorphisms with necrotizing enterocolitis in Chinese Han population.
Gao X, Ma F, Hao H, Dai Y, Liu W, Xiao X, Gao P, Li S. Gao X, et al. Pediatr Neonatol. 2019 Apr;60(2):129-134. doi: 10.1016/j.pedneo.2018.07.002. Epub 2018 Jul 19. Pediatr Neonatol. 2019. PMID: 30100520 Free article. Review.
BACKGROUND: To examine whether polymorphisms in the VEGFA gene lead to low VEGFA production in peripheral blood and increased risk of NEC in the Chinese Han population. ...CONCLUSION: Our results suggested that, if validated in larger studies, screening for VEGFA …
BACKGROUND: To examine whether polymorphisms in the VEGFA gene lead to low VEGFA production in peripheral blood and increased …
Lipid Nanoparticles Deliver the Therapeutic VEGFA mRNA In Vitro and In Vivo and Transform Extracellular Vesicles for Their Functional Extensions.
Nawaz M, Heydarkhan-Hagvall S, Tangruksa B, González-King Garibotti H, Jing Y, Maugeri M, Kohl F, Hultin L, Reyahi A, Camponeschi A, Kull B, Christoffersson J, Grimsholm O, Jennbacken K, Sundqvist M, Wiseman J, Bidar AW, Lindfors L, Synnergren J, Valadi H. Nawaz M, et al. Adv Sci (Weinh). 2023 Apr;10(12):e2206187. doi: 10.1002/advs.202206187. Epub 2023 Feb 19. Adv Sci (Weinh). 2023. PMID: 36806740 Free PMC article.
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