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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1997 1
1999 1
2000 2
2001 1
2003 3
2008 1
2010 2
2011 4
2012 2
2013 1
2014 1
2015 2
2016 2
2022 0
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Page 1
N'-(arylsulfonyl)pyrazoline-1-carboxamidines as novel, neutral 5-hydroxytryptamine 6 receptor (5-HT₆R) antagonists with unique structural features.
van Loevezijn A, Venhorst J, Iwema Bakker WI, de Korte CG, de Looff W, Verhoog S, van Wees JW, van Hoeve M, van de Woestijne RP, van der Neut MA, Borst AJ, van Dongen MJ, de Bruin NM, Keizer HG, Kruse CG. van Loevezijn A, et al. Among authors: venhorst j. J Med Chem. 2011 Oct 27;54(20):7030-54. doi: 10.1021/jm200466r. Epub 2011 Sep 26. J Med Chem. 2011. PMID: 21866910
The selective 5-HT6 receptor antagonist SLV has putative cognitive- and social interaction enhancing properties in rodent models of cognitive impairment.
de Bruin NMWJ, van Loevezijn A, Wicke KM, de Haan M, Venhorst J, Lange JHM, de Groote L, van der Neut MAW, Prickaerts J, Andriambeloson E, Foley AG, van Drimmelen M, van der Wetering M, Kruse CG. de Bruin NMWJ, et al. Among authors: venhorst j. Neurobiol Learn Mem. 2016 Sep;133:100-117. doi: 10.1016/j.nlm.2016.06.020. Epub 2016 Jun 21. Neurobiol Learn Mem. 2016. PMID: 27344942
Optimization of N'-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT6 antagonistic binding pocket.
van Loevezijn A, Venhorst J, Iwema Bakker WI, Lange JHM, de Looff W, Henzen R, de Vries J, van de Woestijne RP, den Hartog AP, Verhoog S, van der Neut MAW, de Bruin NMWJ, Kruse CG. van Loevezijn A, et al. Among authors: venhorst j. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1605-1611. doi: 10.1016/j.bmcl.2016.02.001. Epub 2016 Feb 2. Bioorg Med Chem Lett. 2016. PMID: 26876931
22 results