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Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease.
Venkataraman AV, Mansur A, Rizzo G, Bishop C, Lewis Y, Kocagoncu E, Lingford-Hughes A, Huiban M, Passchier J, Rowe JB, Tsukada H, Brooks DJ, Martarello L, Comley RA, Chen L, Schwarz AJ, Hargreaves R, Gunn RN, Rabiner EA, Matthews PM. Venkataraman AV, et al. Sci Transl Med. 2022 Aug 17;14(658):eabk1051. doi: 10.1126/scitranslmed.abk1051. Epub 2022 Aug 17. Sci Transl Med. 2022. PMID: 35976998
Imaging biomarkers in neurodegeneration: current and future practices.
Young PNE, Estarellas M, Coomans E, Srikrishna M, Beaumont H, Maass A, Venkataraman AV, Lissaman R, Jiménez D, Betts MJ, McGlinchey E, Berron D, O'Connor A, Fox NC, Pereira JB, Jagust W, Carter SF, Paterson RW, Schöll M. Young PNE, et al. Among authors: venkataraman av. Alzheimers Res Ther. 2020 Apr 27;12(1):49. doi: 10.1186/s13195-020-00612-7. Alzheimers Res Ther. 2020. PMID: 32340618 Free PMC article. Review.
Astrocyte reactivity with late-onset cognitive impairment assessed in vivo using 11C-BU99008 PET and its relationship with amyloid load.
Calsolaro V, Matthews PM, Donat CK, Livingston NR, Femminella GD, Guedes SS, Myers J, Fan Z, Tyacke RJ, Venkataraman AV, Perneczky R, Gunn R, Rabiner EA, Gentleman S, Parker CA, Murphy PS, Wren PB, Hinz R, Sastre M, Nutt DJ, Edison P. Calsolaro V, et al. Among authors: venkataraman av. Mol Psychiatry. 2021 Oct;26(10):5848-5855. doi: 10.1038/s41380-021-01193-z. Epub 2021 Jul 15. Mol Psychiatry. 2021. PMID: 34267329 Free PMC article.
Relationship between astrocyte reactivity, using novel 11C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals.
Livingston NR, Calsolaro V, Hinz R, Nowell J, Raza S, Gentleman S, Tyacke RJ, Myers J, Venkataraman AV, Perneczky R, Gunn RN, Rabiner EA, Parker CA, Murphy PS, Wren PB, Nutt DJ, Matthews PM, Edison P. Livingston NR, et al. Among authors: venkataraman av. Mol Psychiatry. 2022 Apr;27(4):2019-2029. doi: 10.1038/s41380-021-01429-y. Epub 2022 Feb 7. Mol Psychiatry. 2022. PMID: 35125495 Free PMC article.