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Covalent Allosteric Probe for the Metabotropic Glutamate Receptor 2: Design, Synthesis, and Pharmacological Characterization.
J Med Chem. 2019 Jan 10;62(1):223-233. doi: 10.1021/acs.jmedchem.8b00051. Epub 2018 Mar 7.
J Med Chem. 2019.
PMID: 29494768
Free PMC article.
Discovery and Kinetic Profiling of 7-Aryl-1,2,4-triazolo[4,3-a]pyridines: Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 2.
Doornbos MLJ, Cid JM, Haubrich J, Nunes A, van de Sande JW, Vermond SC, Mulder-Krieger T, Trabanco AA, Ahnaou A, Drinkenburg WH, Lavreysen H, Heitman LH, IJzerman AP, Tresadern G.
Doornbos MLJ, et al. Among authors: vermond sc.
J Med Chem. 2017 Aug 10;60(15):6704-6720. doi: 10.1021/acs.jmedchem.7b00669. Epub 2017 Aug 1.
J Med Chem. 2017.
PMID: 28704052
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Impact of allosteric modulation: Exploring the binding kinetics of glutamate and other orthosteric ligands of the metabotropic glutamate receptor 2.
Doornbos MLJ, Vermond SC, Lavreysen H, Tresadern G, IJzerman AP, Heitman LH.
Doornbos MLJ, et al. Among authors: vermond sc.
Biochem Pharmacol. 2018 Sep;155:356-365. doi: 10.1016/j.bcp.2018.07.014. Epub 2018 Jul 17.
Biochem Pharmacol. 2018.
PMID: 30028996
Free article.
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