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High folate receptor expression in gliomas can be detected in vivo using folate-based positron emission tomography with high tumor-to-brain uptake ratio divulging potential future targeting possibilities.
Miner MWG, Liljenbäck H, Virta J, Kärnä S, Viitanen R, Elo P, Gardberg M, Teuho J, Saipa P, Rajander J, Mansour HMA, Cleveland NA, Low PS, Li XG, Roivainen A. Miner MWG, et al. Among authors: viitanen r. Front Immunol. 2023 May 18;14:1145473. doi: 10.3389/fimmu.2023.1145473. eCollection 2023. Front Immunol. 2023. PMID: 37275898 Free PMC article.
First-in-Humans Study of 68Ga-DOTA-Siglec-9, a PET Ligand Targeting Vascular Adhesion Protein 1.
Viitanen R, Moisio O, Lankinen P, Li XG, Koivumäki M, Suilamo S, Tolvanen T, Taimen K, Mali M, Kohonen I, Koskivirta I, Oikonen V, Virtanen H, Santalahti K, Autio A, Saraste A, Pirilä L, Nuutila P, Knuuti J, Jalkanen S, Roivainen A. Viitanen R, et al. J Nucl Med. 2021 Apr;62(4):577-583. doi: 10.2967/jnumed.120.250696. Epub 2020 Aug 17. J Nucl Med. 2021. PMID: 32817143 Free PMC article.
The circadian gene Cryptochrome 2 influences stress-induced brain activity and depressive-like behavior in mice.
Sokolowska E, Viitanen R, Misiewicz Z, Mennesson M, Saarnio S, Kulesskaya N, Kängsep S, Liljenbäck H, Marjamäki P, Autio A, Callan SA, Nuutila P, Roivainen A, Partonen T, Hovatta I. Sokolowska E, et al. Among authors: viitanen r. Genes Brain Behav. 2021 Apr;20(4):e12708. doi: 10.1111/gbb.12708. Epub 2020 Oct 26. Genes Brain Behav. 2021. PMID: 33070440 Free article.
Detection of Intestinal Inflammation by Vascular Adhesion Protein-1-Targeted [68Ga]Ga-DOTA-Siglec-9 Positron Emission Tomography in Murine Models of Inflammatory Bowel Disease.
Bhowmik AA, Heikkilä TRH, Polari L, Virta J, Liljenbäck H, Moisio O, Li XG, Viitanen R, Jalkanen S, Koffert J, Toivola DM, Roivainen A. Bhowmik AA, et al. Among authors: viitanen r. Mol Imaging Biol. 2024 Apr;26(2):322-333. doi: 10.1007/s11307-023-01885-8. Epub 2023 Dec 18. Mol Imaging Biol. 2024. PMID: 38110791 Free PMC article.
Hydroxysteroid (17β) dehydrogenase 12 is essential for metabolic homeostasis in adult mice.
Heikelä H, Ruohonen ST, Adam M, Viitanen R, Liljenbäck H, Eskola O, Gabriel M, Mairinoja L, Pessia A, Velagapudi V, Roivainen A, Zhang FP, Strauss L, Poutanen M. Heikelä H, et al. Among authors: viitanen r. Am J Physiol Endocrinol Metab. 2020 Sep 1;319(3):E494-E508. doi: 10.1152/ajpendo.00042.2020. Epub 2020 Jul 21. Am J Physiol Endocrinol Metab. 2020. PMID: 32691632 Free article.
Preclinical Evaluation of 89Zr-Desferrioxamine-Bexmarilimab, a Humanized Antibody Against Common Lymphatic Endothelial and Vascular Endothelial Receptor-1, in a Rabbit Model of Renal Fibrosis.
Moisio O, Virta J, Yatkin E, Liljenbäck H, Palani S, Viitanen R, Miner MWG, Oikonen V, Tolvanen T, Vugts DJ, Taimen P, Li XG, Hollmén M, Jalkanen S, Roivainen A. Moisio O, et al. Among authors: viitanen r. J Nucl Med. 2023 Apr;64(4):555-560. doi: 10.2967/jnumed.122.264725. Epub 2022 Oct 27. J Nucl Med. 2023. PMID: 36302655 Free PMC article.