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mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome.

Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, Morgan PG, Sedensky MM, Kaeberlein M. Johnson SC, et al. Among authors: wasko bm. Science. 2013 Dec 20;342(6165):1524-8. doi: 10.1126/science.1244360. Epub 2013 Nov 14. Science. 2013. PMID: 24231806 Free PMC article.

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Pterocarpus marsupium extract extends replicative lifespan in budding yeast.

Lee MB, Kiflezghi MG, Tsuchiya M, Wasko B, Carr DT, Uppal PA, Grayden KA, Elala YC, Nguyen TA, Wang J, Ragosti P, Nguyen S, Zhao YT, Kim D, Thon S, Sinha I, Tang TT, Tran NHB, Tran THB, Moore MD, Li MAK, Rodriguez K, Promislow DEL, Kaeberlein M. Lee MB, et al. Among authors: wasko b. Geroscience. 2021 Oct;43(5):2595-2609. doi: 10.1007/s11357-021-00418-x. Epub 2021 Jul 23. Geroscience. 2021. PMID: 34297314 Free PMC article.

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Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism.

Yu R, Cao X, Sun L, Zhu JY, Wasko BM, Liu W, Crutcher E, Liu H, Jo MC, Qin L, Kaeberlein M, Han Z, Dang W. Yu R, et al. Among authors: wasko bm. Nat Commun. 2021 Mar 31;12(1):1981. doi: 10.1038/s41467-021-22257-2. Nat Commun. 2021. PMID: 33790287 Free PMC article.

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Yeast replicative aging: a paradigm for defining conserved longevity interventions.

Wasko BM, Kaeberlein M. Wasko BM, et al. FEMS Yeast Res. 2014 Feb;14(1):148-59. doi: 10.1111/1567-1364.12104. Epub 2013 Oct 30. FEMS Yeast Res. 2014. PMID: 24119093 Free PMC article. Review.

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Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast.

Kaya A, Phua CZJ, Lee M, Wang L, Tyshkovskiy A, Ma S, Barre B, Liu W, Harrison BR, Zhao X, Zhou X, Wasko BM, Bammler TK, Promislow DE, Kaeberlein M, Gladyshev VN. Kaya A, et al. Among authors: wasko bm. Elife. 2021 Nov 9;10:e64860. doi: 10.7554/eLife.64860. Elife. 2021. PMID: 34751131 Free PMC article.

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Suppression of telomere capping defects of Saccharomyces cerevisiae yku70 and yku80 mutants by telomerase.

Holland CL, Sanderson BA, Titus JK, Weis MF, Riojas AM, Malczewskyj E, Wasko BM, Lewis LK. Holland CL, et al. Among authors: wasko bm. G3 (Bethesda). 2021 Dec 8;11(12):jkab359. doi: 10.1093/g3journal/jkab359. G3 (Bethesda). 2021. PMID: 34718547 Free PMC article.

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Yeast as a model to understand the interaction between genotype and the response to calorie restriction.

Schleit J, Wasko BM, Kaeberlein M. Schleit J, et al. Among authors: wasko bm. FEBS Lett. 2012 Aug 31;586(18):2868-73. doi: 10.1016/j.febslet.2012.07.038. Epub 2012 Jul 22. FEBS Lett. 2012. PMID: 22828279 Free PMC article. Review.

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Aneuploidy shortens replicative lifespan in Saccharomyces cerevisiae.

Sunshine AB, Ong GT, Nickerson DP, Carr D, Murakami CJ, Wasko BM, Shemorry A, Merz AJ, Kaeberlein M, Dunham MJ. Sunshine AB, et al. Among authors: wasko bm. Aging Cell. 2016 Apr;15(2):317-24. doi: 10.1111/acel.12443. Epub 2016 Jan 13. Aging Cell. 2016. PMID: 26762766 Free PMC article.

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The antifungal plant defensin HsAFP1 induces autophagy, vacuolar dysfunction and cell cycle impairment in yeast.

Struyfs C, Cools TL, De Cremer K, Sampaio-Marques B, Ludovico P, Wasko BM, Kaeberlein M, Cammue BPA, Thevissen K. Struyfs C, et al. Among authors: wasko bm. Biochim Biophys Acta Biomembr. 2020 Aug 1;1862(8):183255. doi: 10.1016/j.bbamem.2020.183255. Epub 2020 Mar 5. Biochim Biophys Acta Biomembr. 2020. PMID: 32145284 Free PMC article.

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DNA sequencing of anatomy lab cadavers to provide hands-on precision medicine introduction to medical students.

Anandakrishnan R, Carpenetti TL, Samuel P, Wasko B, Johnson C, Smith C, Kim J, Michalak P, Kang L, Kinney N, Santo A, Anstrom J, Garner HR, Varghese RT. Anandakrishnan R, et al. Among authors: wasko b. BMC Med Educ. 2020 Nov 16;20(1):437. doi: 10.1186/s12909-020-02366-0. BMC Med Educ. 2020. PMID: 33198737 Free PMC article.

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